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High Throughput Chemistry Lab

Sygnature has a well-established HTC lab which has been efficiently producing small, diverse libraries for the European Lead Factory for the past 5 years.

In the past 5 years Sygnature has produced over 40,000 drug-like molecules with three-dimensional character. Our expertise in this area is available to client projects and is especially useful in the hit-to-lead stage of the drug discovery process.

  • Fully automated process for synthesis, purification and QC
    • Robotic reformatting at each stage
  • Each product traceable throughout the process by barcoded vials
    • Eliminates human / typographic errors
  • Mass-directed purification (ELS/UV option)
    • Single tube collection – compatible with wide range of structures/chromophores
  • Refined protocols for a range of robust reactions
    • Ambient to high temperature, wide range of solvents,
    • Homogeneous and heterogeneous methodologies


Get in Touch

For more details on how we can provide innovative support to your project please use this contact form.

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