Blood Donor Panel
To enable ready access to reliable source of healthy human whole blood and blood-derived cells, Sygnature Discovery has established an internal blood donor panel of healthy volunteers which is supported by our Human Tissue Act Licence. Having this resource in-house aids the development of physiologically relevant and scalable assays for your project.
We have experience isolating and assaying a broad range of blood cell types, including, but not limited to: neutrophils, monocytes, T-cells, NK cells, eosinophils, with experience of working with whole-blood assays.
Sygnature Discovery also has access to fresh access to animal blood via our Strategic Alliance Partners, complimented further by access to disease human blood/tissue from our established relationship with a local Biobank.
Blood-based assays can be tailored to address specific project requirements:
- Fresh vs cryopreserved
- Single donors or pooled
- Different isolation methods fully validated (e.g. SepMate, Leucosep, density gradient sedimentation)
- Ability to identify particular ‘biological’ responders (e.g. proliferation, response to biological stimuli, steroid resistance)
We have a wide range of experience in using healthy or diseased human whole blood or isolated blood cells in a range of different in vitro assay platforms: