Form and Formulation
Here at Sygnature Discovery, we offer specialised expertise in early-stage drug formulation. Leveraging years of experience, we efficiently advance your compounds through preclinical studies and reduce risks as you move into clinical development.
Our talented team of scientists can assist you in crafting robust pre-clinical development strategies. These strategies are tailored to the unique characteristics of each individual Active Pharmaceutical Ingredient (API). Through access to our well-equipped form and formulation development laboratories, we can rapidly and unbiasedly identify the most phase-appropriate development approach. This approach helps to overcome even the most complex bioavailability or stability challenges.
Working closely with our colleagues in Process Chemistry and Scale-Up, Drug Metabolism and Pharmacokinetics (DMPK), Pharmacology, and Separation Science, we can apply the right tools to solve the most complex challenges in your project.
Form and Formulation Services
The Form and Formulation team is prepared to expedite your molecule’s journey from the lab to the clinic. We offer comprehensive suite of services designed to accelerate and mitigate risks in your project.
Our range of services include:
- Solid Form Analysis
- Polymorph Screening
- Salt and co-crystal Screening
- CMC Activities
- Pre-clinical formulation with delivery to in-vivo pharmacology
- Early clinical formulation