Biochemical Assays

Our bioscientists are well versed in the development and maintenance of robust tailored assays spanning a plethora of enzyme targets.

Sourced, either off the shelf from commercial vendors or developed in-house to fit our clients’ requirements, our experienced scientists provide high-quality biochemical assays and informed data interpretation across the discovery pipeline.

We can offer a variety of scalable enzyme activity assays (product formation and detection) and Binding Assays using industry-standard instrumentation platforms across multiple enzyme classes

Enzyme Activity Assays:

• Kinase
• Methyltransferase
• HDAC/HAT
• Demethylase
• Protease
• PDE
• Phosphatase
• DUB
• Others
  

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Binding Assays:

• Radiolabel binding
• Fluorescence Polarisation (FP) binding assays
• Nuclear Hormone
• Ion Channels
• Others

Technologies:

• BRET (bioluminescence resonance energy transfer), NanoBRET™, HTRF (homogeneous time-resolved fluorescence).
• Fluorescence Intensity, Absorbance, Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET), LC-MS (liquid chromatography–mass spectrometry).
• AlphaScreen® (amplified luminescent proximity homogeneous assay).