Bioscience

Our in-depth bioscience knowledge of target biology, therapeutic area specialism, and experience of working collaboratively at each stage of the drug discovery pipeline allows the efficient design and implementation of tailored high-quality assays, which help to accelerate your drug discovery programs.

Our bioscientist team is staffed by highly experienced bioscientists (over 80% PhDs), many with 10-20 years of drug discovery experience gained in pharmaceutical research (from AstraZeneca, Takeda, GSK, Merck, Novartis, Pfizer, Prosidion and many more).  More than 25% of the department has over 15 years’ first-hand industry experience in discovering new drugs, both small molecules and biologicals across a broad range of therapeutic areas and biological target classes.  Your drug discovery projects are in safe hands at Sygnature Discovery.

• We can assist you in screening your novel compounds for a range of project-specific properties, such as cellular function and isolated target engagement characteristics.
• Utilise the very latest technologies to minimise the risk of drug failure later in the drug discovery pipeline.
• Offer a broad spectrum of adaptable capabilities to help you reach success with your drug discovery target in a variety of therapeutic areas.

As bioscientist pride ourselves in delivering high-quality consistent assay data to measure Structure-Activity Relationships (SAR) and define compound Mechanism of Action (MOA) to help drive your project forward.  All project data linked to experimental write-ups are stored within a powerful online Dotmatics-based web portal that gives secure access to your biological data regardless of your geographical location.

Sygnature Discovery’s Bioscience Department forms part of the talented Integrated Drug Discovery team that can enhance your drug discovery project at any stage of the process.  You will benefit from being able to access bench bioscientists directly and our bioscientist work collaboratively to address scientific needs so that your drug discovery program is given the best opportunity for success.

We have established a broad range of industry-standard in-house capabilities including bioscience, which complemented by cutting-edge technology platforms and supported by our in-depth drug discovery expertise, allow us to add value to your drug discovery program. Our team is continually enhancing the suite of capabilities available to you, mirroring the evolving discovery landscape, always ensuring that the technical expertise and drug discovery know-how underpin each of our platforms.