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A Tale of Two Libraries: How can complementary collections drive success in lead identification?

With Dr Louise Birch, Principal Scientist, Computational Chemistry

High-throughput screening (HTS) can be an efficient means to rapidly identify promising compounds, however the quality and diversity of the libraries screened ultimately determines the number and value of the hits.

But after the screen, how do we best perform fast follow-up, rapidly expand our hits to aid early understanding of the SAR, and best prioritise resources?

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