What is Happening in High Throughput Screening at Sygnature Discovery?

At Sygnature Discovery, our High Throughput Screening (HTS) group, established in 2019 couples industry-leading advanced laboratory automation with a fully integrated informatics platform and Genedata Screener® analysis software to provide a closed-loop workflow to facilitate the high-fidelity screening of our chemical libraries.

This poster provides an insight into the wide range of target classes, technologies and therapeutic areas we have prosecuted in prior HTS campaigns, including a high proportion of complex cell-based assays. We provide information on the quality and ongoing QC of the Sygnature compound libraries including LeadFinder Diversity 150K as well as example screening data.