Seeking New Glues – Toward a Ligase-Agnostic Platform for Molecular Glue Degrader Discovery

Unlock the Undruggable with Ligase-Agnostic Glue Degrader Discovery

Molecular glue degraders (MGDs) offer a powerful path to degrade previously “undruggable” targets. Yet most MGDs have been found by chance—until now.

Discover how Sygnature Discovery’s ligase-agnostic discovery platform integrates high-throughput screening, semi-automated target ID, and LiP-MS to turn serendipity into strategy—rapidly identifying novel MGDs and their recruited ligases.

👉 Download the free poster and explore our next-gen approach to targeted protein degradation.