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Compound Profile of 61 Libraries Delivered to ELF

Abstract

The European Lead Factory (ELF) is a project of the Innovative Medicines Initiative (IMI) and is aimed at boosting drug discovery in Europe through the generation of a state-of-the-art high-throughput screening (HTS) collection of 500,000 compounds. 300,000 of these compounds are being donated by pharmaceutical companies and 200,000 are being generated in collaboration between academic groups and small and medium enterprises (SMEs) with Sygnature Discovery committed to delivering 40,000 compounds by the end of 2017. Here, the properties of 61 libraries synthesised at Sygnature Discovery, below termed the Sygnature set, are discussed.

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