Sygnature Discovery > News and Resources > Posters > From Paper to Assay: A Case Study on Adapting, Developing and Troubleshooting an Enzymatic Assay for High-Throughput Screening

From Paper to Assay: A Case Study on Adapting, Developing and Troubleshooting an Enzymatic Assay for High-Throughput Screening

Step into the future of enzymatic assays with our comprehensive poster. This detailed resource unveils our journey in optimizing a high-throughput assay for measuring cyclic nucleotide phosphodiesterase (PDE) activity. From adapting to a 384-well format to integrating automated liquid handling, discover how we enhanced the assay’s efficiency, accuracy, and throughput. Our rigorous testing not only increased the number of compounds tested per plate but also improved detection capabilities for high pico-molar inhibitors. This poster is a must-have for researchers and professionals in biochemistry and drug discovery, offering valuable insights and practical solutions for advancing your enzymatic assay methodologies. Download now and elevate your approach to enzymatic assays.

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