Case Studies

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Development of a High-Throughput Screening Platform for Kv2.2 Drug Discovery
Development of a High-Throughput Screening Platform for Kv2.2 Drug Discovery
Advancing Kv2.2 Drug Discovery Sygnature Discovery’s ion channel screening platform provides reliable, high-quality data to…
Case Studies
High-Throughput Electrophysiology Solutions for TRPML Drug Discovery
High-Throughput Electrophysiology Solutions for TRPML Drug Discovery
Sygnature Discovery’s TRPML drug discovery platform delivers comprehensive solutions for advancing TRPML1, TRPML2 and TRPML3…
Case Studies
Advanced Electrophysiology Solutions for PAT-1 Drug Discovery
Advanced Electrophysiology Solutions for PAT-1 Drug Discovery
Advance PAT-1 Drug Discovery with Custom Transporter Assays and High-Throughput Screening The proton-coupled amino acid…
Case Studies
Validating a High-Throughput iPSC-Derived DRG Electrophysiology Platform
Validating a High-Throughput iPSC-Derived DRG Electrophysiology Platform
Translational Relevance of iPSC-Derived Sensory Neurons To address the critical need for scalable and human-relevant…
Case Studies
Production of Active VHL and Analysis by SPR
Production of Active VHL and Analysis by SPR
Proximity Based Therapeutics Proximity based therapeutics have emerged as powerful tools in drug discovery and…
Case Studies
Inflammatory Cytokines Analysis through Sygnature Discovery’s LPS model
Inflammatory Cytokines Analysis through Sygnature Discovery’s LPS model
Pain models, by their intrinsic nature, frequently embody an inflammatory component. This inflammation is mediated…
Case Studies
Explore the effective mice model of cytokine release during inflammation
Explore the effective mice model of cytokine release during inflammation
Inflammation is a complex biological response of the body’s immune system to harmful stimuli, such…
Case Studies
Sygnature Discovery’s Mouse-Formalin Model
Sygnature Discovery’s Mouse-Formalin Model
The mouse-formalin pain model stands as a chemically-evoked acute pain model within our research arsenal…
Case Studies
Sygnature Discovery’s MIA joint pain model 
Sygnature Discovery’s MIA joint pain model 
The MIA joint pain model, as orchestrated at Sygnature Discovery, serves as a robust and…
Case Studies
Sygnature Discovery’s Tail-Immersion Model
Sygnature Discovery’s Tail-Immersion Model
The tail-immersion pain model is a well-known approach in the exploration of thermally-evoked acute pain.
Case Studies
Sygnature Discovery’s Carrageenan Model
Sygnature Discovery’s Carrageenan Model
Sygnature Discovery’s carrageenan pain model stands as an ideal model in the study of inflammation…
Case Studies
Building up a higher-throughput enzymatic assay
Building up a higher-throughput enzymatic assay
Introduction We were tasked with developing a higher-throughput assay from a client. The assay is…
Case Studies
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