It’s important to lay strong foundations for successful drug discovery at this first stage of the process. Our integrated target identification and validation platform combines AI with expert insights, and rigorous lab validation to guide targets through robust evaluation, ready for hit discovery.
Validated, high-quality hits, delivered through integrated technologies and expert collaboration, give you a confident starting point for faster drug discovery.
Turning promising leads into clinical candidates with speed, precision, and the scientific expertise to generate high-quality data and deliver real patient impact.
Discover precise insights into brain neurochemistry with Sygnature Discovery's in vivo microdialysis and cOFM services. With over 20 years of expertise, we design bespoke studies that reveal how compounds modulate neurotransmitter systems in health and disease. Using UHPLC/HPLC with electrochemical detection or mass spectrometry, we deliver robust PK/PD data to support confident CNS decision making.
Delivering integrated, modality-agnostic drug discovery to tackle complex biology, accelerate development, and advance innovative therapies with confidence.
Advancing next-generation ADCs through payload-focused design, integrated expertise, and collaborative innovation to deliver safer, more selective therapies.
Driving biologics innovation through integrated design, structural biology, and multidisciplinary expertise to accelerate next-generation therapies from concept to clinic.
Combining deep therapeutic expertise with translational insight to design strategies, reduce risk, and accelerate discovery programs toward clinical success.
Accelerating oncology drug discovery through integrated expertise, innovative modalities, and translational insight to deliver candidates with real clinical impact.
Driving immunology and inflammation drug discovery through tailored assays, translational models, and integrated expertise for faster clinical success.
Advancing CNS drug discovery through integrated models, translational biomarkers, and multidisciplinary expertise to overcome complexity and accelerate therapeutic innovation.
Designing and advancing differentiated small-molecule therapies for obesity and diabetes through integrated expertise, mechanistic insight, and translational strategies.
Inobrodib, an exciting, first-in-class oral anti-cancer drug in clinical development by CellCentric, was collaboratively designed, synthesised and supported on its pre-clinical journey by an integrated project team at Sygnature Discovery. Inobrodib is now showing promising results in Phase I and II trials for multiple myeloma and other cancer types.
It’s important to lay strong foundations for successful drug discovery at this first stage of the process. Our integrated target identification and validation platform combines AI with expert insights, and rigorous lab validation to guide targets through robust evaluation, ready for hit discovery.
Validated, high-quality hits, delivered through integrated technologies and expert collaboration, give you a confident starting point for faster drug discovery.
Turning promising leads into clinical candidates with speed, precision, and the scientific expertise to generate high-quality data and deliver real patient impact.
Delivering integrated, modality-agnostic drug discovery to tackle complex biology, accelerate development, and advance innovative therapies with confidence.
Advancing next-generation ADCs through payload-focused design, integrated expertise, and collaborative innovation to deliver safer, more selective therapies.
Driving biologics innovation through integrated design, structural biology, and multidisciplinary expertise to accelerate next-generation therapies from concept to clinic.
Combining deep therapeutic expertise with translational insight to design strategies, reduce risk, and accelerate discovery programs toward clinical success.
Accelerating oncology drug discovery through integrated expertise, innovative modalities, and translational insight to deliver candidates with real clinical impact.
Driving immunology and inflammation drug discovery through tailored assays, translational models, and integrated expertise for faster clinical success.
Advancing CNS drug discovery through integrated models, translational biomarkers, and multidisciplinary expertise to overcome complexity and accelerate therapeutic innovation.
Designing and advancing differentiated small-molecule therapies for obesity and diabetes through integrated expertise, mechanistic insight, and translational strategies.
Inobrodib, an exciting, first-in-class oral anti-cancer drug in clinical development by CellCentric, was collaboratively designed, synthesised and supported on its pre-clinical journey by an integrated project team at Sygnature Discovery. Inobrodib is now showing promising results in Phase I and II trials for multiple myeloma and other cancer types.
AI Meets Expertise: A hybrid Workflow For Modern Target ID | QIAGEN & Sygnature
In drug discovery, generating targets is no longer the challenge. The real question is how to identify the few worth investing months of research and significant resources to pursue. Hear expert perspectives on how AI, pathway analysis and scientific expertise are shaping modern target identification.
When AI Produces Hundreds of Answers: Turning Insight into Action
AI-driven workflows can identify hundreds of potential therapeutic targets in minutes.
But quantity doesn’t equal confidence.
A target may appear statistically compelling while hiding critical biological risks, tissue-specific safety concerns or clinical limitations that only emerge through deeper investigation.
The question isn’t: “Can AI find targets?”
It’s: “How do you identify the targets worth pursuing and eliminate those that aren’t?”
In this 45-minute fireside chat, experts from Sygnature Discovery and QIAGEN Digital Insights share their perspectives on the evolving role of AI in target identification. Drawing on their combined expertise in bioinformatics, pathway analysis, translational biology, and drug discovery, the panel explores the practical challenges of moving from AI-generated target lists to confident, evidence-based decisions.
Through real-world examples and discussion, viewers will gain insights into how scientific expertise, experimental validation, and data-driven analysis can be combined to improve target prioritization, reduce risk, and support more effective drug discovery programs.
Senior Scientist 2 Computational Sciences and Informatics Sygnature Discovery
Dr Saurav Saha specialises in bioinformatics and computational biology, with a focus on enabling data-driven target discovery. He leads bioinformatics activities within cross-functional teams, developing and integrating scalable analytical workflows that support drug discovery programs. Saurav also plays a key role in mentoring scientists and growing bioinformatics capability, combining technical expertise with a collaborative approach to advancing computational strategies in research.
Dr Daniel Bakowski has over seven years of experience at Sygnature Discovery, where he leads projects across target identification, validation, and early-stage drug discovery. With a strong background in molecular and cellular biology, pharmacology, and biochemistry, he has extensive expertise in assay development, high-throughput screening, and lead optimisation. Daniel is a seasoned project leader, known for driving innovative approaches in complex discovery programs within the biotechnology and pharmaceutical sectors.
Iman Bhattacharya leads marketing initiatives across clinical genomics, AI-driven decision support, and data science platforms. His work spans oncology, hereditary disease, and drug discovery, helping translate complex technologies into impactful solutions for healthcare and life sciences. Iman collaborates closely with product, sales, and ecosystem partners to drive go-to-market strategy and advance innovation in precision medicine.
Senior Manager, QDI Field Application Scientist QIAGEN
Olivia Alder supports researchers in extracting meaningful insights from complex omics data. With a strong focus on the discovery portfolio, she has extensive experience guiding scientific teams in data interpretation and application. A passionate advocate for clean, reliable data, Olivia helps bridge the gap between advanced technologies and real-world research outcomes.
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