{"id":13258,"date":"2024-05-22T09:50:00","date_gmt":"2024-05-22T09:50:00","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/?post_type=webinar-and-podcast&p=13258"},"modified":"2026-01-23T16:03:01","modified_gmt":"2026-01-23T16:03:01","slug":"benefits-of-measuring-mitochondrial-function-two-different-approaches","status":"publish","type":"webinar-and-podcast","link":"https:\/\/www.sygnaturediscovery.com\/fr\/webinar-and-podcast\/benefits-of-measuring-mitochondrial-function-two-different-approaches\/","title":{"rendered":"Benefits of Measuring Mitochondrial Function – Two Different Approaches"},"content":{"rendered":"\n

Measuring mitochondrial function required sensitivity, specificity, and models that reflect real biological conditions. In Episode 2, Tatiana introduces two complementary in vitro <\/em>approaches and explains how each reveals different aspects of metabolic health. She highlights how tracking metabolites such as ATP, ADP, NADH, pyruvate, and lactate helps build a clearer picture of energy maintenance and cellular stress.<\/p>\n\n\n\n

About Tatiana<\/h3>\n\n\n\n
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Tatiana Rosenstock has had an exceptional career and has made significant contributions to the field of Neuroscience for 20+ years. Her work has focused on topics such as mitochondrial deregulation, transcription deregulation, and autophagy in neurodegenerative diseases, such as Huntington\u2019s Disease, and Amyotrophic Lateral Sclerosis, and Schizophrenia.  <\/p>\n\n\n\n

At Sygnature Discovery, Tatiana is a Principal Scientist overseeing various neuroscience-related projects in different sub-areas such as metabolism (mitochondrial function), biomarkers, microglial function and activation, and neuroplasticity. During this period, she has been working with distinct in-vitro models, named iPSC-derived neurons, primary cortical neurons, Alzheimer`s and Parkinson`s disease fibroblasts, neuroblastomas cell lines, tissue and biofluids from transgenics animal models of Alzheimer`s disease. <\/p>\n<\/div>\n<\/div>\n\n\n\n

What You’ll Learn<\/h2>\n\n\n\n
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  • Two practical methods for measuring mitochondrial function in vitro <\/em><\/li>\n\n\n\n
  • How energy metabolites reveal shifts in mitochondrial health<\/li>\n\n\n\n
  • When to choose one approach over another <\/li>\n<\/ul>\n\n\n
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