{"id":13963,"date":"2019-05-02T08:45:51","date_gmt":"2019-05-02T08:45:51","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/synnature-discovery-prolonge-son-soutien-au-projet-esculab-lusine-europeenne-de-production-de-plomb\/"},"modified":"2026-02-11T09:47:14","modified_gmt":"2026-02-11T09:47:14","slug":"synnature-discovery-prolonge-son-soutien-au-projet-esculab-lusine-europeenne-de-production-de-plomb","status":"publish","type":"post","link":"https:\/\/www.sygnaturediscovery.com\/fr\/synnature-discovery-prolonge-son-soutien-au-projet-esculab-lusine-europeenne-de-production-de-plomb\/","title":{"rendered":"Synnature Discovery prolonge son soutien au projet ESCulab, l’usine europ\u00e9enne de production de plomb."},"content":{"rendered":"

L’European Lead Factory, la plus grande plateforme collaborative de d\u00e9couverte de m\u00e9dicaments en Europe, poursuit son ascension fulgurante.<\/strong><\/p>\n

L\u2019 European Lead Factory<\/a> (ELF) a obtenu un budget total de 36,5 millions d\u2019euros pour son projet dans le cadre du deuxi\u00e8me programme de l\u2019Initiative pour les m\u00e9dicaments innovants (IMI). Au cours des 5 prochaines ann\u00e9es, 20 partenaires dans 7 pays feront progresser la transformation de cibles m\u00e9dicamenteuses potentielles en nouveaux m\u00e9dicaments dans le cadre du nouveau projet ESCulab (European Screening Centre : biblioth\u00e8que unique pour une biologie attractive) sous la marque European Lead Factory.<\/p>\n

Jon de Vlieger, coordinateur du consortium ESCulab \u00e0 Lygature, a d\u00e9clar\u00e9 : \u00ab C\u2019est un r\u00e9el plaisir de poursuivre l\u2019int\u00e9gration de propositions novatrices de criblage et de fournir aux chercheurs et aux PME de toute l\u2019Europe des points de d\u00e9part de grande qualit\u00e9 pour la d\u00e9couverte de m\u00e9dicaments. Afin d\u2019\u00e9largir notre champ d\u2019action, nous ne nous contentons plus des approches cibl\u00e9es, mais nous int\u00e9grons d\u00e9sormais \u00e9galement les criblages ph\u00e9notypiques. \u00bb<\/em><\/p>\n

<\/em>Plateforme \u00e9prouv\u00e9e pour les nouvelles id\u00e9es intelligentes<\/strong><\/p>\n

Les universit\u00e9s, les organismes de recherche et les PME disposent d’un large \u00e9ventail de cibles th\u00e9rapeutiques potentielles, mais peinent \u00e0 acc\u00e9der \u00e0 des chimioth\u00e8ques et des plateformes de criblage adapt\u00e9es. Les entreprises pharmaceutiques ont besoin de cibles de haute qualit\u00e9 pour proposer des th\u00e9rapies innovantes aux patients. L’European Lead Factory associe, dans le cadre d’un partenariat public-priv\u00e9, les vastes chimioth\u00e8ques de haute qualit\u00e9 issues de l’industrie pharmaceutique et de la Collection publique de compos\u00e9s, ainsi que la principale plateforme de criblage d’Europe, aux cibles innovantes d\u00e9tenues par les organismes acad\u00e9miques. Cette initiative offre une plateforme id\u00e9ale pour transformer la recherche biologique fondamentale en phases pr\u00e9liminaires en points de d\u00e9part cr\u00e9dibles et prometteurs pour les campagnes de d\u00e9couverte de m\u00e9dicaments. <\/p>\n

Stefan Jaroch, chef de projet chez Bayer AG, confirme que : \u00ab l\u2019European Lead Factory a clairement d\u00e9montr\u00e9 comment le crowdsourcing et l\u2019intelligence collective peuvent effectivement faire progresser les concepts biologiques vers des projets de d\u00e9couverte de m\u00e9dicaments qui profitent au monde universitaire, \u00e0 l\u2019industrie, \u00e0 la soci\u00e9t\u00e9 et, en fin de compte, aux patients. \u00bb<\/em><\/p>\n

Nouvelles id\u00e9es + Nouveaux partenaires = Nouvelles opportunit\u00e9s <\/strong><\/p>\n

Au cours des cinq prochaines ann\u00e9es, l’European Lead Factory lancera 185 nouveaux projets de d\u00e9couverte de m\u00e9dicaments en criblant des cibles m\u00e9dicamenteuses pertinentes issues de chercheurs europ\u00e9ens, de petites et moyennes entreprises et de l’industrie pharmaceutique \u00e0 l’aide de la biblioth\u00e8que ELF de 550 000 compos\u00e9s chimiques uniques.<\/p>\n

Le succ\u00e8s du concept de l’European Lead Factory a d\u00e9j\u00e0 incit\u00e9 d’autres partenaires priv\u00e9s \u00e0 le rejoindre. Le projet ESCulab accueille les deux entreprises pharmaceutiques Servier et Gr\u00fcnenthal ainsi que Medicines for Malaria Venture (MMV), le principal partenariat de d\u00e9veloppement de produits dans le domaine de la recherche et du d\u00e9veloppement de m\u00e9dicaments antipaludiques. <\/p>\n

Tim Wells, directeur scientifique de MMV, ajoute :<\/em> \u00ab Nous sommes ravis de participer \u00e0 ESCulab et \u00e0 l\u2019European Lead Factory, qui repr\u00e9sentent une opportunit\u00e9 de nouveaux partenariats pour MMV, tant avec l\u2019UE via IMI qu\u2019avec diverses entreprises tr\u00e8s innovantes. Ces partenariats donnent acc\u00e8s \u00e0 une chimioth\u00e8que in\u00e9dite et de grande qualit\u00e9, dont le criblage contre des cibles prioritaires contre le paludisme est essentiel selon nous. \u00bb<\/em><\/p>\n

Geraint Jones, directeur de la chimie chez Sygnature, d\u00e9clare : \u00ab Nous sommes ravis de continuer \u00e0 soutenir cette initiative en fournissant des compos\u00e9s \u00e0 la collaboration. Nous avons h\u00e2te de jouer un r\u00f4le actif dans ce partenariat prometteur avec l\u2019European Lead Factory afin de relever certains des plus grands d\u00e9fis de la recherche et de l\u2019innovation m\u00e9dicales. \u00bb <\/em><\/p>\n

 <\/p>\n

\u00c0 propos de l’usine de plomb europ\u00e9enne<\/strong><\/p>\n

L’European Lead Factory est une plateforme paneurop\u00e9enne de d\u00e9couverte de m\u00e9dicaments qui donne un coup de pouce majeur \u00e0 la recherche de m\u00e9dicaments en Europe en reliant des cibles m\u00e9dicamenteuses innovantes \u00e0 une biblioth\u00e8que de compos\u00e9s de haute qualit\u00e9 et \u00e0 des installations de criblage \u00e0 haut d\u00e9bit.<\/p>\n

Pour en savoir plus sur la d\u00e9couverte collaborative de m\u00e9dicaments, veuillez consulter le site www.europeanleadfactory.eu<\/a> .<\/p>\n

Reconnaissance du soutien <\/strong><\/p>\n

Ce projet a b\u00e9n\u00e9fici\u00e9 d’un financement de l’ Initiative conjointe pour les m\u00e9dicaments innovants 2 (IMI 2)<\/a> au titre de la convention de subvention n\u00b0 806948 : \u00ab ESCulab : Centre europ\u00e9en de criblage ; Biblioth\u00e8que unique pour une biologie attractive \u00bb.<\/em> Cette IMI 2 re\u00e7oit le soutien du programme de recherche et d’innovation Horizon 2020 de l’Union europ\u00e9enne, de la F\u00e9d\u00e9ration europ\u00e9enne des industries et associations pharmaceutiques (EFPIA) et de l’initiative \u00ab M\u00e9dicaments contre le paludisme \u00bb.<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"category":[29],"tags":[1291,1289,824,1293,1297,1271,1295,1299,1012,1290,1188,1267],"class_list":["post-13963","post","type-post","status-publish","format-standard","hentry","category-non-categorise","tag-bibliotheques-de-composes-de-haute-qualite","tag-decouverte-collaborative-de-medicaments","tag-decouverte-de-la-signature","tag-entreprise-de-medicaments-contre-le-paludisme","tag-industrie-pharmaceutique-2","tag-initiative-pour-les-medicaments-innovants","tag-nouveaux-partenaires","tag-partenariat-public-prive","tag-plateforme-de-decouverte-de-medicaments","tag-projet-esculab","tag-projets-de-decouverte-de-medicaments","tag-usine-de-plomb-europeenne"],"acf":[],"yoast_head":"\nSynnature Discovery prolonge son soutien au projet ESCulab, l'usine europ\u00e9enne de production de plomb. - 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