{"id":13954,"date":"2017-05-02T09:16:39","date_gmt":"2017-05-02T09:16:39","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/synnature-discovery-renforce-ses-capacites-en-biophysique-avec-lintroduction-du-systeme-spr-biacore-8k\/"},"modified":"2026-02-11T09:45:41","modified_gmt":"2026-02-11T09:45:41","slug":"synnature-discovery-renforce-ses-capacites-en-biophysique-avec-lintroduction-du-systeme-spr-biacore-8k","status":"publish","type":"post","link":"https:\/\/www.sygnaturediscovery.com\/fr\/synnature-discovery-renforce-ses-capacites-en-biophysique-avec-lintroduction-du-systeme-spr-biacore-8k\/","title":{"rendered":"Synnature Discovery renforce ses capacit\u00e9s en biophysique avec l’introduction du syst\u00e8me SPR Biacore 8K."},"content":{"rendered":"

\"\"<\/p>\n

Sygnature Discovery, le plus grand fournisseur ind\u00e9pendant du Royaume-Uni de ressources et d’expertise int\u00e9gr\u00e9es en mati\u00e8re de d\u00e9couverte de m\u00e9dicaments, a renforc\u00e9 ses capacit\u00e9s en biophysique gr\u00e2ce \u00e0 l’ajout du syst\u00e8me SPR Biacore 8K<\/a> de GE Healthcare au syst\u00e8me SPR Biacore T200 que la soci\u00e9t\u00e9 poss\u00e8de d\u00e9j\u00e0 en interne.<\/p>\n

Dernier-n\u00e9 de la gamme Biacore de GE Healthcare, le Biacore 8K fournit efficacement des donn\u00e9es de liaison de haute qualit\u00e9 pour le criblage et la caract\u00e9risation de petites mol\u00e9cules et de produits biologiques. Ce syst\u00e8me de r\u00e9sonance plasmonique de surface (RPS) haute sensibilit\u00e9 fournit rapidement des donn\u00e9es de cin\u00e9tique et d’affinit\u00e9, r\u00e9duisant ainsi le d\u00e9lai d’obtention des r\u00e9sultats jusqu’\u00e0 huit fois par rapport aux syst\u00e8mes \u00e0 aiguille unique. La flexibilit\u00e9 et le d\u00e9bit \u00e9lev\u00e9s du syst\u00e8me permettent de r\u00e9duire la dur\u00e9e du cycle exp\u00e9rimental, m\u00eame pour les cibles complexes. <\/p>\n

Le Dr Scott Pollack,<\/a> directeur associ\u00e9 des biosciences chez Sygnature Discovery, a comment\u00e9 :<\/p>\n

Le Biacore 8K est l’instrument Biacore le plus avanc\u00e9 de GE Healthcare. Gr\u00e2ce \u00e0 ses huit aiguilles d’injection, le syst\u00e8me peut r\u00e9aliser 64 titrages d’affinit\u00e9 en 3 \u00e0 5 heures, soit jusqu’\u00e0 128 titrages par jour ou 640 (320 pour n=2) par semaine en fonctionnement continu. Il permet \u00e9galement d’effectuer des tests de concentration unique (par exemple, des criblages de fragments) d’une dur\u00e9e de 4 heures par plaque 384 puits, soit jusqu’\u00e0 2 300 par jour. <\/p>\n

En plus du d\u00e9lai de traitement des donn\u00e9es clients plus rapide que permet cette capacit\u00e9, la configuration \u00e0 8 aiguilles et l’algorithme intelligent d’injection d’ABA acc\u00e9l\u00e8rent \u00e9galement le d\u00e9veloppement des tests en permettant de tester en parall\u00e8le un large \u00e9ventail de conditions (par exemple, la recherche de tampons) et sont id\u00e9aux pour l’analyse de la comp\u00e9tition des compos\u00e9s (mode d’action).<\/p>\n

L’ajout du Biacore 8K \u00e0 notre Biacore T200 signifie que Sygnature Discovery est l’une des CRO de d\u00e9couverte de m\u00e9dicaments les mieux \u00e9quip\u00e9es au Royaume-Uni offrant des services biophysiques.<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":13955,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"category":[790,1262],"tags":[1268,1266,1241,1277,1270,824,1275,1273,1279,1264],"class_list":["post-13954","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bioscience","category-essais-biophysiques","tag-capacite-en-biophysique","tag-caracterisation-biologique","tag-criblage-a-haut-debit","tag-criblage-de-petites-molecules","tag-cro-de-decouverte-de-medicaments","tag-decouverte-de-la-signature","tag-donnees-cinetiques-et-daffinite","tag-ge-healthcare","tag-services-biophysiques-du-royaume-uni","tag-systeme-biacore-8k-spr"],"acf":[],"yoast_head":"\nSynnature Discovery renforce ses capacit\u00e9s en biophysique avec l'introduction du syst\u00e8me SPR Biacore 8K. - 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