{"id":13818,"date":"2022-03-24T13:04:35","date_gmt":"2022-03-24T13:04:35","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/500-et-ce-nest-pas-fini\/"},"modified":"2026-02-11T09:50:33","modified_gmt":"2026-02-11T09:50:33","slug":"500-et-ce-nest-pas-fini","status":"publish","type":"post","link":"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/","title":{"rendered":"500 \u2013 et ce n’est pas fini !"},"content":{"rendered":"

Lorsque Lynette Ongeri, scientifique sp\u00e9cialis\u00e9e en DMPK, a rejoint Sygnature ce mois-ci, elle nous a involontairement aid\u00e9s \u00e0 franchir une \u00e9tape importante dont nous sommes extr\u00eamement fiers\u2026<\/p>\n

Sygnature Discovery \u2013 ou Sygnature Chemical Services Ltd, comme on l\u2019appelait alors \u2013 a ouvert ses portes en 2004 avec cinq collaborateurs.<\/p>\n

\"Sygnature
Le premier logo de Sygnature<\/p>\n

Sous la direction de son fondateur Simon Hirst, ce petit groupe de chimie ambitieux a d\u00e9marr\u00e9 sur les chapeaux de roue, d\u00e9veloppant rapidement des relations solides avec ses clients et s’\u00e9tendant \u00e0 d’autres sp\u00e9cialit\u00e9s scientifiques comme la chimie computationnelle.<\/p>\n

Pourtant, alors que de nombreuses entreprises d\u00e9marrent en force avant de s’essouffler ou de perdre leur \u00e9lan, le plus remarquable concernant notre entreprise est peut-\u00eatre la fa\u00e7on dont notre croissance s’est maintenue \u2013 et m\u00eame acc\u00e9l\u00e9r\u00e9e au fil des ans.<\/p>\n

Aujourd’hui, ce groupe de cinq personnes est devenu une \u00e9quipe multidisciplinaire et multinationale d’au moins 500 collaborateurs, r\u00e9partis sur deux sites au Royaume-Uni et poss\u00e9dant une expertise dans tous les domaines, de la DMPK \u00e0 la pharmacologie in vivo<\/em> , en passant par les biosciences, la forme et la formulation<\/a> .<\/p>\n

Pas mal pour seulement 18 ans.<\/p>\n

Mais qu’en est-il de l’employ\u00e9e num\u00e9ro 500 ? \u00c0 bien des \u00e9gards, l’histoire de Lynette Ongeri refl\u00e8te le d\u00e9veloppement m\u00eame de Sygnature. <\/p>\n

L’attrait de l’int\u00e9gration<\/h2>\n

Originaire du Kenya mais fi\u00e8re Yorkshirewoman \u2013 Leeds est devenue sa ville natale \u00e0 l’\u00e2ge de 12 ans \u2013 Lynette a obtenu sa licence en pharmacologie \u00e0 l’Universit\u00e9 de Sheffield en 2005.<\/p>\n

De l\u00e0, elle est entr\u00e9e dans l’industrie en rejoignant UCB Pharma \u00e0 Cambridge en tant qu’associ\u00e9e de recherche, passant deux ans dans l’entreprise avant de commencer la plus longue p\u00e9riode de sa carri\u00e8re (\u00e0 ce jour) chez Charles River, o\u00f9 Lynette a \u00e9t\u00e9 scientifique ADME senior pendant un peu moins d’une d\u00e9cennie.<\/p>\n

Ce passage de l’industrie pharmaceutique traditionnelle \u00e0 une CRO correspond en quelque sorte \u00e0 nos propres d\u00e9buts ; apr\u00e8s avoir travaill\u00e9 chez AstraZeneca et OSI Pharmaceuticals, Simon Hirst a d\u00e9cid\u00e9 de cr\u00e9er Sygnature, une nouvelle CRO qui ferait les choses diff\u00e9remment.<\/p>\n

Revenons \u00e0 Lynette.<\/p>\n

Apr\u00e8s avoir occup\u00e9 les postes de chef d’\u00e9quipe chez Pharmaron puis de scientifique principale chez Concept Life Sciences, elle a r\u00e9cemment rejoint notre \u00e9quipe \u00e0 Alderley Park en tant que scientifique senior III.<\/p>\n

\"ParcAlderley Park, o\u00f9 Lynette travaille pour Sygnature<\/p>\n

Alors pourquoi Sygnature ?<\/p>\n

\u00ab Ce qui m\u2019a surtout attir\u00e9e ici, c\u2019est l\u2019opportunit\u00e9 de travailler sur des projets int\u00e9gr\u00e9s de d\u00e9couverte de m\u00e9dicaments \u00bb, a d\u00e9clar\u00e9 Lynette.<\/p>\n

\u00ab Par le pass\u00e9, j\u2019ai principalement travaill\u00e9 sur des projets r\u00e9mun\u00e9r\u00e9s \u00e0 l\u2019acte, o\u00f9 la prise de d\u00e9cision se faisait en interne. \u00bb<\/p>\n

\u00ab Je souhaitais m\u2019impliquer davantage dans ce processus, approfondir mes connaissances sur les diff\u00e9rentes pi\u00e8ces du puzzle de la d\u00e9couverte de m\u00e9dicaments et collaborer davantage avec des scientifiques de toutes les disciplines. \u00bb<\/p>\n

\u00ab J\u2019ai h\u00e2te de pouvoir participer aux r\u00e9unions de projet une fois que je serai install\u00e9e \u00bb, a d\u00e9clar\u00e9 Lynette.<\/p>\n

\u00ab Mes coll\u00e8gues des d\u00e9partements de DMPK, de biosciences et de chimie se r\u00e9unissent tous et travaillent ensemble pour trouver de nouvelles solutions et surmonter tous les obstacles \u2013 exactement ce qui m\u2019a attir\u00e9 vers une carri\u00e8re ici. \u00bb<\/p>\n

Perspectives d’avenir<\/h2>\n

Mais qu’en est-il de l’avenir ?<\/p>\n

\u00ab J\u2019ai une grande exp\u00e9rience des transporteurs de drogue, un domaine sur lequel je me suis beaucoup concentr\u00e9e ces cinq \u00e0 huit derni\u00e8res ann\u00e9es \u00bb, a d\u00e9clar\u00e9 Lynette.<\/p>\n

\u00ab C\u2019est un sujet br\u00fblant, de plus en plus consid\u00e9r\u00e9 comme ayant une importance \u00e9gale \u00e0 celle des enzymes classiques. Je suis donc int\u00e9ress\u00e9 \u00e0 mettre mon expertise \u00e0 profit pour aider Sygnature dans ses projets concernant les transporteurs de m\u00e9dicaments. \u00bb<\/p>\n

Quant \u00e0 son nouvel employeur, l’avenir semble prometteur en termes de croissance et d’expansion.<\/p>\n

Conform\u00e9ment \u00e0 nos ambitieux plans de croissance, nous recrutons actuellement pour diff\u00e9rents postes scientifiques, \u00e0 la fois sur le site de Lynette \u00e0 Alderley Park dans le Cheshire et sur notre site BioCity \u00e0 Nottingham.<\/p>\n

L’investissement de Five Arrows Principal Investments l’an dernier<\/a> signifie qu’aucun ralentissement n’est en vue, avec une demande constante de la part des clients du monde entier et de nombreux projets passionnants qui devraient d\u00e9marrer prochainement.<\/p>\n

Le cap des 500 employ\u00e9s a \u00e9t\u00e9 franchi.<\/p>\n

Seul l’avenir nous dira quand nous atteindrons les 1 000, mais ce ne sera probablement plus tr\u00e8s long !<\/p>\n

Envie de rejoindre Lynette au sein d’une CRO innovante sp\u00e9cialis\u00e9e dans la d\u00e9couverte de m\u00e9dicaments int\u00e9gr\u00e9e ? Nous recrutons<\/a> \u2026 <\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":13820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"category":[29],"tags":[],"class_list":["post-13818","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-categorise"],"acf":[],"yoast_head":"\n500 \u2013 et ce n'est pas fini ! - Sygnature<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"500 \u2013 et ce n'est pas fini ! - Sygnature\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\" \/>\n<meta property=\"og:site_name\" content=\"Sygnature\" \/>\n<meta property=\"article:published_time\" content=\"2022-03-24T13:04:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-11T09:50:33+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Lynette-Ongeri1-2-scaled-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"2169\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"pnpd-admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"pnpd-admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\"},\"author\":{\"name\":\"pnpd-admin\",\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/person\/9c173ed9f4225ab61ea895ac3a939448\"},\"headline\":\"500 \u2013 et ce n’est pas fini !\",\"datePublished\":\"2022-03-24T13:04:35+00:00\",\"dateModified\":\"2026-02-11T09:50:33+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\"},\"wordCount\":816,\"publisher\":{\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Lynette-Ongeri1-2-scaled-1.jpg\",\"articleSection\":[\"Non cat\u00e9goris\u00e9\"],\"inLanguage\":\"fr-CA\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\",\"url\":\"https:\/\/www.sygnaturediscovery.com\/fr\/500-et-ce-nest-pas-fini\/\",\"name\":\"500 \u2013 et ce n'est pas fini ! 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