{"id":13646,"date":"2025-07-24T10:37:04","date_gmt":"2025-07-24T10:37:04","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/synnature-discovery-acheve-une-importante-modernisation-de-ses-installations-de-chimie-a-haut-debit-suite-a-un-investissement-dun-million-de-livres-sterling\/"},"modified":"2026-02-11T09:43:54","modified_gmt":"2026-02-11T09:43:54","slug":"synnature-discovery-acheve-une-importante-modernisation-de-ses-installations-de-chimie-a-haut-debit-suite-a-un-investissement-dun-million-de-livres-sterling","status":"publish","type":"post","link":"https:\/\/www.sygnaturediscovery.com\/fr\/synnature-discovery-acheve-une-importante-modernisation-de-ses-installations-de-chimie-a-haut-debit-suite-a-un-investissement-dun-million-de-livres-sterling\/","title":{"rendered":"Synnature Discovery ach\u00e8ve une importante modernisation de ses installations de chimie \u00e0 haut d\u00e9bit suite \u00e0 un investissement d&rsquo;un million de livres sterling."},"content":{"rendered":"\n<p><strong><span style=\"font-size: 18pt;\">Sygnature Discovery, une organisation de recherche contractuelle (CRO) de premier plan dans le domaine de la d\u00e9couverte int\u00e9gr\u00e9e de m\u00e9dicaments, annonce aujourd&rsquo;hui la finalisation d&rsquo;une am\u00e9lioration majeure de ses capacit\u00e9s de chimie \u00e0 haut d\u00e9bit (HTC) et de son infrastructure de laboratoire suite \u00e0 un investissement de 1 million de livres sterling.<\/span><\/strong><\/p>\n\n<p><span style=\"font-size: 14pt;\">Dans le contexte actuel de la recherche pharmaceutique, o\u00f9 les r\u00e9sultats sont particuli\u00e8rement exigeants, acc\u00e9l\u00e9rer la mise sur le march\u00e9 des m\u00e9dicaments reste une priorit\u00e9 absolue. La plateforme de chimie \u00e0 haut d\u00e9bit (HTC) am\u00e9lior\u00e9e de Sygnature a doubl\u00e9 sa capacit\u00e9 de synth\u00e8se et de purification, permettant ainsi de produire deux fois plus de compos\u00e9s dans les m\u00eames d\u00e9lais. Cette mise \u00e0 niveau offre aux clients un acc\u00e8s plus rapide \u00e0 des compos\u00e9s de haute qualit\u00e9, facilitant la prise de d\u00e9cision et acc\u00e9l\u00e9rant les progr\u00e8s vers les essais cliniques.  <\/span><\/p>\n\n<p><span style=\"font-size: 14pt;\">Les plateformes HTC exploitent des syst\u00e8mes automatis\u00e9s pour synth\u00e9tiser et purifier efficacement de grands volumes de compos\u00e9s. Int\u00e9gr\u00e9es \u00e0 la plateforme de criblage \u00e0 haut d\u00e9bit (HTS) interne de Sygnature, qui \u00e9value rapidement les chimioth\u00e8ques par rapport \u00e0 des cibles biologiques, ces technologies peuvent acc\u00e9l\u00e9rer l&rsquo;identification de candidats m\u00e9dicaments prometteurs. <\/span><\/p>\n\n<p><span style=\"font-size: 14pt;\">L&rsquo;un des piliers de cet investissement est l&rsquo;int\u00e9gration de la chromatographie en phase supercritique (SFC) \u00e0 la plateforme HTC de Sygnature. Bien que la SFC soit de plus en plus r\u00e9pandue, peu de plateformes HTC l&rsquo;utilisent pour la purification. Sygnature propose d\u00e9sormais des options de purification par phase inverse et par SFC, offrant une flexibilit\u00e9 in\u00e9gal\u00e9e et des conditions de purification optimales. Malgr\u00e9 la complexit\u00e9 des infrastructures et l&rsquo;expertise requises pour les syst\u00e8mes SFC, Sygnature reste d\u00e9termin\u00e9e \u00e0 fournir des solutions d&rsquo;excellence.     <\/span><\/p>\n\n<p><span style=\"font-size: 14pt;\">Les installations modernis\u00e9es seront pleinement op\u00e9rationnelles \u00e0 partir du mois d&rsquo;ao\u00fbt et marqueront une \u00e9tape importante dans la strat\u00e9gie de croissance continue de Sygnature.<\/span><\/p>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-000-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"TestimonialCard TestimonialCard--centered has-text-base-font-size has-border-radius has-padding-top has-padding-bottom has-padding-right has-padding-left\" style=\"color:var(--wp--preset--color--white);background-color:var(--wp--preset--color--dark-blue-700);border-radius:var(--wp--preset--spacing--30);padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50);padding-right:clamp(3rem, 13vw, 15rem);padding-left:clamp(3rem, 13vw, 15rem);font-size:var(--wp--preset--font-size--text-base);\">\n\n                    <div class=\"TestimonialCard__centered text-center\">\n                        \n                            <blockquote class=\"TestimonialCard__quote relative max-w-4xl mx-auto text-center mb-10 md:mb-12 xl:mb-16\">\n                    <div class=\"relative z-10 has-text-3-xl-font-size leading-tight\"><p>Our successful track record over the past 20 years on client projects demonstrates our ability to validate robust syntheses and utilize automated processes to deliver high-quality science quickly and efficiently.<\/p>\n<p>This investment in our capabilities further enhances the value for our customers and reinforces our commitment to delivering cutting-edge services. Our customers want to partner with a CRO that will help them hit their milestones. This expansion proves we are that partner. We have the facilities, flexibility, and scientific excellence to deliver.<\/p>\n<\/div>\n                <\/blockquote>\n                        \n            <div class=\"TestimonialCard__avatar flex justify-center\">\n                <figure class=\"Avatar flex items-center text-left group md:min-w-64 -small \"\n       style=\"\"\n       itemscope itemtype=\"https:\/\/schema.org\/Person\">\n        <div class=\"Avatar__Image w-16 h-16 rounded-full overflow-hidden mr-6 flex-shrink-0\">\n        <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Geraint-Jones-3-1-150x150.png 150w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/png\"><img decoding=\"async\" width=\"150\" height=\"150\" class=\"w-full object-cover\" alt=\"Profile picture of Geraint Jones\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" itemprop=\"image\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Geraint-Jones-3-1.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Geraint-Jones-3-1-150x150.png 150w\"><\/picture>\n    <\/div>\n        <figcaption class=\"Avatar__Content\">\n        <h4 class=\"mb-1 font-medium\" itemprop=\"name\">Geraint Jones<\/h4>\n                    <p class=\"opacity-80 !mb-0\" itemprop=\"jobTitle\">Director of Chemistry<\/p>\n            <\/figcaption>\n<\/figure>\n\n            <\/div>\n        <\/div>\n        \n    <\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n<p>\u00a0<\/p>\n\n<p><span style=\"font-size: 14pt;\">Geraint Jones, directeur de la chimie chez Sygnature Discovery, a comment\u00e9 : \u00ab Notre exp\u00e9rience r\u00e9ussie au cours des 20 derni\u00e8res ann\u00e9es sur des projets clients d\u00e9montre notre capacit\u00e9 \u00e0 valider des synth\u00e8ses robustes et \u00e0 utiliser des processus automatis\u00e9s pour fournir des r\u00e9sultats scientifiques de haute qualit\u00e9 rapidement et efficacement. \u00bb<\/span><\/p>\n\n<p><span style=\"font-size: 14pt;\">\u00ab Cet investissement dans nos capacit\u00e9s renforce la valeur ajout\u00e9e pour nos clients et t\u00e9moigne de notre engagement \u00e0 fournir des services de pointe. Nos clients recherchent un partenaire CRO capable de les aider \u00e0 atteindre leurs objectifs. Cette expansion prouve que nous sommes ce partenaire. Nous disposons des installations, de la flexibilit\u00e9 et de l&rsquo;excellence scientifique n\u00e9cessaires pour y parvenir. \u00bb<\/span><\/p>\n\n<p>\u00a0<\/p>\n\n<p><strong><span style=\"font-size: 18pt;\">\u00c0 propos de Sygnature Discovery<\/span><\/strong><\/p>\n\n<p><strong><span style=\"font-size: 18pt;\">Sygnature Discovery est une organisation de recherche contractuelle int\u00e9gr\u00e9e de premier plan dans le domaine de la d\u00e9couverte de m\u00e9dicaments, bas\u00e9e au Royaume-Uni et au Canada, avec son si\u00e8ge social \u00e0 Nottingham (Royaume-Uni). D&rsquo;autres sites sont situ\u00e9s \u00e0 Alderley Park, Macclesfield et Glasgow (Royaume-Uni), ainsi qu&rsquo;\u00e0 Montr\u00e9al et Qu\u00e9bec (Canada). Son \u00e9quipe de plus de 1 000 employ\u00e9s, dont 900 scientifiques, collabore avec des organisations mondiales de biotechnologie, pharmaceutiques et \u00e0 but non lucratif. Depuis 2011, Sygnature Discovery a mis au point 56 nouveaux compos\u00e9s pr\u00e9cliniques et 35 compos\u00e9s cliniques, et ses scientifiques sont cit\u00e9s dans plus de 235 brevets. Ses domaines d&rsquo;expertise th\u00e9rapeutique comprennent l&rsquo;oncologie, l&rsquo;inflammation et l&rsquo;immunologie, les neurosciences, les maladies m\u00e9taboliques, les maladies infectieuses, les maladies fibrotiques, et bien plus encore.<\/span><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":13647,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"category":[797,791],"tags":[],"class_list":["post-13646","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-chemistry","category-high-throughput-chemistry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Synnature Discovery ach\u00e8ve une importante modernisation de ses installations de chimie \u00e0 haut d\u00e9bit suite \u00e0 un 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