{"id":4168,"date":"2025-07-09T17:05:54","date_gmt":"2025-07-09T17:05:54","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/poster\/small-molecules-big-impact-advancing-obesity-disease-drug-discovery\/"},"modified":"2026-01-22T13:56:08","modified_gmt":"2026-01-22T13:56:08","slug":"small-molecules-big-impact-advancing-obesity-disease-drug-discovery","status":"publish","type":"poster","link":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/small-molecules-big-impact-advancing-obesity-disease-drug-discovery\/","title":{"rendered":"Small Molecules, Big Impact: Advancing Obesity Drug Discovery"},"content":{"rendered":"<p><span style=\"font-family: arial, helvetica, sans-serif;\">Explore cutting-edge insights into small molecule innovations driving obesity and weight loss treatments. As obesity remains a complex and challenging therapeutic area, advances in small molecule drug discovery offer unparalleled promise\u2014exemplified by breakthroughs like Eli Lilly\u2019s oral GLP-1 receptor agonist, Orforglipron.<\/span><\/p>\n<p><span style=\"font-family: arial, helvetica, sans-serif;\">This poster outlines:<\/span><\/p>\n<ul data-spread=\"false\">\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">The transformative potential of small molecules for CNS-targeted weight management therapies.<\/span><\/li>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">Strategies to overcome drug discovery challenges, including polypharmacology, membrane-bound targets, and complex PK\/DDI profiles.<\/span><\/li>\n<li><span style=\"font-family: arial, helvetica, sans-serif;\">The critical advantage of integrated, co-located interdisciplinary teams (uniting pharmacologists, medicinal chemists, and DMPK experts) to accelerate informed decision-making and compound optimization.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-family: arial, helvetica, sans-serif;\">Gain exclusive insights and accelerate your research!<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":2920,"template":"","category":[709,705,682,771,683,723,740,747,690,685,678,754,736,686,741,704,688,695],"class_list":["post-4168","poster","type-poster","status-publish","has-post-thumbnail","hentry","category-cell-based-assays","category-cell-line-generation","category-chemistry","category-cryo-em","category-dmpk","category-drug-drug-interactions","category-ex-vivo-tissue-analysis","category-gpcrs","category-hit-identification","category-in-vivo-pharmacology","category-integrated-drug-discovery","category-metabolic-disease","category-metabolic-disease-models","category-modalities","category-small-moleucles","category-structural-biology","category-therapeutic-areas","category-virtual-screening"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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