{"id":3972,"date":"2020-06-25T11:51:17","date_gmt":"2020-06-25T11:51:17","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/"},"modified":"2025-12-12T11:37:03","modified_gmt":"2025-12-12T11:37:03","slug":"comparing-hts-novel-immuno-oncology-target-hpk1","status":"publish","type":"poster","link":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/","title":{"rendered":"Comparing HTS with the Novel Immuno-Oncology Target HPK1: Unveiling Diverse Chemical Starting Points for Potent Inhibitor Development"},"content":{"rendered":"<h2><strong>High Throughput Screening (HTS) System for Hit Identification at Sygnature Discovery<\/strong><\/h2>\n<p>At Sygnature Discovery, we have recently implemented a new, state-of-the-art High Throughput Screening (HTS) system, designed to complement our existing hit finding capabilities.<\/p>\n<h3><strong>Advanced HTS System for Rapid Hit Identification<\/strong><\/h3>\n<p>The integration of HighRes Biosolutions automation platform, Titian Mosaic compound management software, and Genedata data processing enables rapid and robust hit identification from our custom-designed LeadFinder library of 150k compounds. Discover the capabilities of this system through our robust screening cascade.<\/p>\n<h3><strong>New Starting Points for HPK1 Inhibitor Development<\/strong><\/h3>\n<p>The HTS system has successfully identified several new starting points for HPK1 inhibitor development. These structures show differentiation from those in the reported HPK1 patent literature.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>a HTS versus the novel immuno-oncology target hpk1 identifies a range of chemical starting points for the development of potent-inhibitors.<\/p>\n","protected":false},"featured_media":2626,"template":"","category":[1],"class_list":["post-3972","poster","type-poster","status-publish","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster<\/title>\n<meta name=\"description\" content=\"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster\" \/>\n<meta property=\"og:description\" content=\"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/\" \/>\n<meta property=\"og:site_name\" content=\"Sygnature\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-12T11:37:03+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Novel-Inhibitor-for-HPK1-via-HTS.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"988\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/\",\"name\":\"HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Novel-Inhibitor-for-HPK1-via-HTS.jpg\",\"datePublished\":\"2020-06-25T11:51:17+00:00\",\"dateModified\":\"2025-12-12T11:37:03+00:00\",\"description\":\"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/#breadcrumb\"},\"inLanguage\":\"fr-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Novel-Inhibitor-for-HPK1-via-HTS.jpg\",\"contentUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Novel-Inhibitor-for-HPK1-via-HTS.jpg\",\"width\":1500,\"height\":988},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/comparing-hts-novel-immuno-oncology-target-hpk1\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/page-daccueil\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Comparing HTS with the Novel Immuno-Oncology Target HPK1: Unveiling Diverse Chemical Starting Points for Potent Inhibitor Development\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"name\":\"Sygnature Discovery\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\"},\"alternateName\":\"Sygnature\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-CA\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\",\"name\":\"Sygnature\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"width\":1,\"height\":1,\"caption\":\"Sygnature\"},\"image\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster","description":"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/","og_locale":"fr_CA","og_type":"article","og_title":"HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster","og_description":"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.","og_url":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/","og_site_name":"Sygnature","article_modified_time":"2025-12-12T11:37:03+00:00","og_image":[{"width":1500,"height":988,"url":"http:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Novel-Inhibitor-for-HPK1-via-HTS.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Estimation du temps de lecture":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/","url":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/","name":"HTS Reveals Novel HPK1 Inhibitor Starting Points - Poster","isPartOf":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/#primaryimage"},"image":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/#primaryimage"},"thumbnailUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Novel-Inhibitor-for-HPK1-via-HTS.jpg","datePublished":"2020-06-25T11:51:17+00:00","dateModified":"2025-12-12T11:37:03+00:00","description":"Cutting-edge HTS system rapidly identifies hit compounds from our LeadFinder library, offering new HPK1 inhibitor starting points.","breadcrumb":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/#breadcrumb"},"inLanguage":"fr-CA","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/"]}]},{"@type":"ImageObject","inLanguage":"fr-CA","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/#primaryimage","url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Novel-Inhibitor-for-HPK1-via-HTS.jpg","contentUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Novel-Inhibitor-for-HPK1-via-HTS.jpg","width":1500,"height":988},{"@type":"BreadcrumbList","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/comparing-hts-novel-immuno-oncology-target-hpk1\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.sygnaturediscovery.com\/fr\/page-daccueil\/"},{"@type":"ListItem","position":2,"name":"Comparing HTS with the Novel Immuno-Oncology Target HPK1: Unveiling Diverse Chemical Starting Points for Potent Inhibitor Development"}]},{"@type":"WebSite","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","name":"Sygnature Discovery","description":"","publisher":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization"},"alternateName":"Sygnature","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.sygnaturediscovery.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-CA"},{"@type":"Organization","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization","name":"Sygnature","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-CA","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","contentUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","width":1,"height":1,"caption":"Sygnature"},"image":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster\/3972","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster"}],"about":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/types\/poster"}],"version-history":[{"count":0,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster\/3972\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/media\/2626"}],"wp:attachment":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/media?parent=3972"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/category?post=3972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}