{"id":3858,"date":"2017-09-15T09:25:45","date_gmt":"2017-09-15T09:25:45","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/"},"modified":"2025-12-12T11:34:46","modified_gmt":"2025-12-12T11:34:46","slug":"3d-cell-assays-valuable-tool-drug-discovery","status":"publish","type":"poster","link":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/","title":{"rendered":"A Valuable Tool for Drug Discovery: 3D Cell Assays"},"content":{"rendered":"<p>Abstract<\/p>\n<p>Traditional cell assays in a 2D monolayer have proven invaluable for drug screening, but cannot replicate the 3D tumour microenvironment.<\/p>\n<p>Factors such as hypoxia, heterogeneous cell populations, soluble factor\u00a0gradients, extracellular matrix, and waste and nutrient diffusion can change cell behaviour and response to compound treatment1. As a result, cells grown in 2D are not as physiologically relevant, and important\u00a0discoveries may be either misinterpreted or missed completely. Profiling drug candidates in 3D may yield more biologically relevant data and may allow for better discrimination between different drug candidates. This\u00a0could reduce the likelihood of failure at later stages of development, saving time and money.<\/p>\n<p>A 3D assay could provide a more enhanced model for drug profiling and would provide a bridge between in vitro and in vivo assays typically performed in drug discovery screening cascades.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Discover the potential of 3D assay technology for drug screening, bridging the gap between in vitro and in vivo assays. Explore how factors like hypoxia, cell heterogeneity, and extracellular matrix influence cell behaviour, leading to more biologically relevant data. Adopting 3D assays may enhance drug candidate profiling, reducing the risk of failure and saving time and resources in drug development.<\/p>\n","protected":false},"featured_media":2482,"template":"","category":[1],"class_list":["post-3858","poster","type-poster","status-publish","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Enhancing Drug Discovery: Utilising 3D Cell Assays<\/title>\n<meta name=\"description\" content=\"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Enhancing Drug Discovery: Utilising 3D Cell Assays\" \/>\n<meta property=\"og:description\" content=\"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/\" \/>\n<meta property=\"og:site_name\" content=\"Sygnature\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-12T11:34:46+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Screen-Shot-2018-03-08-at-10.24.45.png\" \/>\n\t<meta property=\"og:image:width\" content=\"784\" \/>\n\t<meta property=\"og:image:height\" content=\"1114\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/\",\"name\":\"Enhancing Drug Discovery: Utilising 3D Cell Assays\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Screen-Shot-2018-03-08-at-10.24.45.png\",\"datePublished\":\"2017-09-15T09:25:45+00:00\",\"dateModified\":\"2025-12-12T11:34:46+00:00\",\"description\":\"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/#breadcrumb\"},\"inLanguage\":\"fr-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Screen-Shot-2018-03-08-at-10.24.45.png\",\"contentUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Screen-Shot-2018-03-08-at-10.24.45.png\",\"width\":784,\"height\":1114,\"caption\":\"3D Cell Assays: A Valuable Tool for Drug Discovery\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/poster\\\/3d-cell-assays-valuable-tool-drug-discovery\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/page-daccueil\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"A Valuable Tool for Drug Discovery: 3D Cell Assays\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"name\":\"Sygnature Discovery\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\"},\"alternateName\":\"Sygnature\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-CA\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\",\"name\":\"Sygnature\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"width\":1,\"height\":1,\"caption\":\"Sygnature\"},\"image\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Enhancing Drug Discovery: Utilising 3D Cell Assays","description":"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/","og_locale":"fr_CA","og_type":"article","og_title":"Enhancing Drug Discovery: Utilising 3D Cell Assays","og_description":"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.","og_url":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/","og_site_name":"Sygnature","article_modified_time":"2025-12-12T11:34:46+00:00","og_image":[{"width":784,"height":1114,"url":"http:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Screen-Shot-2018-03-08-at-10.24.45.png","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Estimation du temps de lecture":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/","url":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/","name":"Enhancing Drug Discovery: Utilising 3D Cell Assays","isPartOf":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/#primaryimage"},"image":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/#primaryimage"},"thumbnailUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Screen-Shot-2018-03-08-at-10.24.45.png","datePublished":"2017-09-15T09:25:45+00:00","dateModified":"2025-12-12T11:34:46+00:00","description":"The power of 3D assay technology for drug screening, providing more biologically relevant data and bridging in vitro and in vivo assays.","breadcrumb":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/#breadcrumb"},"inLanguage":"fr-CA","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/"]}]},{"@type":"ImageObject","inLanguage":"fr-CA","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/#primaryimage","url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Screen-Shot-2018-03-08-at-10.24.45.png","contentUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Screen-Shot-2018-03-08-at-10.24.45.png","width":784,"height":1114,"caption":"3D Cell Assays: A Valuable Tool for Drug Discovery"},{"@type":"BreadcrumbList","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/3d-cell-assays-valuable-tool-drug-discovery\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.sygnaturediscovery.com\/fr\/page-daccueil\/"},{"@type":"ListItem","position":2,"name":"A Valuable Tool for Drug Discovery: 3D Cell Assays"}]},{"@type":"WebSite","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","name":"Sygnature Discovery","description":"","publisher":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization"},"alternateName":"Sygnature","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.sygnaturediscovery.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-CA"},{"@type":"Organization","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization","name":"Sygnature","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-CA","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","contentUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","width":1,"height":1,"caption":"Sygnature"},"image":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster\/3858","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster"}],"about":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/types\/poster"}],"version-history":[{"count":0,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/poster\/3858\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/media\/2482"}],"wp:attachment":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/media?parent=3858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/category?post=3858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}