{"id":22589,"date":"2025-11-16T08:00:24","date_gmt":"2025-11-16T08:00:24","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/poster\/plateformes-dimagerie-a-haut-debit-pour-levaluation-de-la-neuroplasticite-dans-la-decouverte-precoce-de-medicaments\/"},"modified":"2026-11-12T14:20:47","modified_gmt":"2026-11-12T14:20:47","slug":"plateformes-dimagerie-a-haut-debit-pour-levaluation-de-la-neuroplasticite-dans-la-decouverte-precoce-de-medicaments","status":"publish","type":"poster","link":"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/plateformes-dimagerie-a-haut-debit-pour-levaluation-de-la-neuroplasticite-dans-la-decouverte-precoce-de-medicaments\/","title":{"rendered":"Plateformes d&rsquo;imagerie \u00e0 haut d\u00e9bit pour l&rsquo;\u00e9valuation de la neuroplasticit\u00e9 dans la d\u00e9couverte pr\u00e9coce de m\u00e9dicaments"},"content":{"rendered":"<p data-start=\"345\" data-end=\"413\"><span style=\"font-family: arial, helvetica, sans-serif;\">Acc\u00e9l\u00e9ration du d\u00e9pistage de la neuroplasticit\u00e9 gr\u00e2ce \u00e0 des mod\u00e8les <em>in vitro<\/em> \u00e9volutifs<\/span><\/p>\n<p data-start=\"415\" data-end=\"764\"><span style=\"font-family: arial, helvetica, sans-serif;\">La neuroplasticit\u00e9 structurelle et fonctionnelle est un moteur essentiel du d\u00e9veloppement et de l&rsquo;adaptation c\u00e9r\u00e9brale, mais son \u00e9tude efficace aux premiers stades de la d\u00e9couverte de m\u00e9dicaments demeure complexe. Ce poster pr\u00e9sente la plateforme d&rsquo;imagerie \u00e0 haut d\u00e9bit semi-automatis\u00e9e de Sygnature Discovery, qui quantifie la croissance des neurites dans des mod\u00e8les de neurones primaires et de cellules PC12 et SH-SY5Y.<\/span><\/p>\n<p data-start=\"766\" data-end=\"1034\"><span style=\"font-family: arial, helvetica, sans-serif;\">Le r\u00e9sultat ? Un outil robuste et \u00e9volutif pour le criblage ph\u00e9notypique des modulateurs de la neuroplasticit\u00e9, acc\u00e9l\u00e9rant l&rsquo;identification de nouvelles th\u00e9rapies pour les troubles neuropsychiatriques et neurod\u00e9g\u00e9n\u00e9ratifs, avec la possibilit\u00e9 de s&rsquo;\u00e9tendre au m\u00e9tabolisme, \u00e0 la neuroinflammation et au-del\u00e0.<\/span><\/p>\n<p data-start=\"1036\" data-end=\"1144\"><span style=\"font-family: arial, helvetica, sans-serif;\">T\u00e9l\u00e9chargez l&rsquo;affiche gratuite pour d\u00e9couvrir comment cette plateforme fait le lien entre la recherche fondamentale et les neurosciences translationnelles.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":22591,"template":"","category":[790,817,843,818],"class_list":["post-22589","poster","type-poster","status-publish","has-post-thumbnail","hentry","category-bioscience","category-domaines-therapeutiques","category-essais-cellulaires","category-neuroscience"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.8 (Yoast SEO v28.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Imagerie \u00e0 haut d\u00e9bit pour le d\u00e9pistage de la neuroplasticit\u00e9 | Poster<\/title>\n<meta name=\"description\" content=\"Quantification semi-automatis\u00e9e de la croissance des neurites dans les mod\u00e8les de neurones PC12, SH-SY5Y et primaires pour le criblage de modulateurs de la neuroplasticit\u00e9. En savoir plus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/plateformes-dimagerie-a-haut-debit-pour-levaluation-de-la-neuroplasticite-dans-la-decouverte-precoce-de-medicaments\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Plateformes d&#039;imagerie \u00e0 haut d\u00e9bit pour l&#039;\u00e9valuation de la neuroplasticit\u00e9 dans la d\u00e9couverte pr\u00e9coce de m\u00e9dicaments\" \/>\n<meta property=\"og:description\" content=\"Quantification semi-automatis\u00e9e de la croissance des neurites dans les mod\u00e8les de neurones PC12, SH-SY5Y et primaires pour le criblage de modulateurs de la neuroplasticit\u00e9. 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