{"id":8815,"date":"2025-12-12T11:26:07","date_gmt":"2025-12-12T11:26:07","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/canaux-ioniques\/tmem175\/"},"modified":"2026-01-27T15:13:23","modified_gmt":"2026-01-27T15:13:23","slug":"tmem175","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/","title":{"rendered":"TMEM175"},"content":{"rendered":"\n<div x-data='subNav({\"anchor_map\":{\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/recepteurs-gabaa-alternative\\\/\":\"R\\u00e9cepteurs GABAA\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/recepteurs-nmda\\\/\":\"R\\u00e9cepteurs NMDA\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/recepteurs-de-glycine\\\/\":\"R\\u00e9cepteurs de la glycine\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/recepteurs-nicotiniques\\\/\":\"R\\u00e9cepteurs nicotiniques\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/canaux-trp\\\/\":\"Cha\\u00eenes TRP\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/canaux-de-sodium\\\/\":\"Canaux sodiques\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/canaux-calciques\\\/\":\"Canaux calciques\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/canaux-potassiques\\\/\":\"Canaux potassiques\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/canaux-chlorure\\\/\":\"Canaux chlorure\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/\":\"TMEM175\"}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" false x-cloak style=\"\">\n    <div x-ref=\"fixedNav\" class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/\" class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Canaux ioniques<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/' === window.location.href ? '-active' : ''\">\n                                            R\u00e9cepteurs GABAA\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/' === window.location.href ? '-active' : ''\">\n                                            R\u00e9cepteurs NMDA\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/' === window.location.href ? '-active' : ''\">\n                                            R\u00e9cepteurs de la glycine\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/' === window.location.href ? '-active' : ''\">\n                                            R\u00e9cepteurs nicotiniques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/' === window.location.href ? '-active' : ''\">\n                                            Cha\u00eenes TRP\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/' === window.location.href ? '-active' : ''\">\n                                            Canaux sodiques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/' === window.location.href ? '-active' : ''\">\n                                            Canaux calciques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/' === window.location.href ? '-active' : ''\">\n                                            Canaux potassiques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/' === window.location.href ? '-active' : ''\">\n                                            Canaux chlorure\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/' === window.location.href ? '-active' : ''\">\n                                            TMEM175\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                    <\/ul>\n                        \n                        <div x-ref=\"scrollIndicator\" class=\"scroll-indicator\" x-show=\"showScrollIndicator\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0 transform translate-x-full\" x-transition:enter-end=\"opacity-100 transform translate-x-0\">\n                            <svg class=\"chevron-icon w-4 h-4\" viewbox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                                <path d=\"M5.65306 3.53025L10.6531 8.53025C10.7227 8.60018 10.7775 8.68297 10.8154 8.77414C10.8533 8.8653 10.8735 8.96304 10.8735 9.06175C10.8735 9.16046 10.8533 9.2582 10.8154 9.34936C10.7775 9.44053 10.7227 9.52332 10.6531 9.59325L5.65306 14.5932C5.51217 14.7341 5.32107 14.8133 5.12181 14.8133C4.92255 14.8133 4.73145 14.7341 4.59056 14.5932C4.44966 14.4523 4.37051 14.2612 4.37051 14.062C4.37051 13.8627 4.44966 13.6716 4.59056 13.5307L9.06294 9.06175L4.59056 4.59325C4.44966 4.45236 4.37051 4.26126 4.37051 4.062C4.37051 3.86274 4.44966 3.67164 4.59056 3.53075C4.73145 3.38985 4.92255 3.3107 5.12181 3.3107C5.32107 3.3107 5.51217 3.38985 5.65306 3.53075V3.53025Z\" fill=\"currentColor\"><\/path>\n                            <\/svg>\n                        <\/div>\n                    <\/div>\n                <\/div>\n            <\/div>\n\n            <!-- Mobile menu button -->\n            <button x-ref=\"navMenuButton\" type=\"button\" class=\"flex justify-center items-center py-2 whitespace-nowrap pl-5 pr-2.5 ml-auto md:hidden\" aria-label=\"Show more navigation items\" :aria-expanded=\"mobileSubMenuOpen\">\n                <span class=\"sr-only pr-2 inline-block\">More<\/span>\n\n                <svg class=\"transition duration-500 ease-in-out\" :class=\"mobileSubMenuOpen ? 'rotate-180' : ''\" width=\"16\" height=\"16\" viewbox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                <path d=\"M13.5306 6.53025L8.5306 11.5302C8.46092 11.6002 8.37813 11.6556 8.28696 11.6935C8.1958 11.7314 8.09806 11.7508 7.99935 11.7508C7.90064 11.7508 7.8029 11.7314 7.71173 11.6935C7.62057 11.6556 7.53778 11.6002 7.4681 11.5302L2.4681 6.53025C2.3272 6.38935 2.24805 6.19825 2.24805 5.999C2.24805 5.79974 2.3272 5.60864 2.4681 5.46775C2.60899 5.32685 2.80009 5.2477 2.99935 5.2477C3.19861 5.2477 3.3897 5.32685 3.5306 5.46775L7.99997 9.93712L12.4693 5.46712C12.6102 5.32623 12.8013 5.24707 13.0006 5.24707C13.1999 5.24707 13.391 5.32623 13.5318 5.46712C13.6727 5.60802 13.7519 5.79911 13.7519 5.99837C13.7519 6.19763 13.6727 6.38873 13.5318 6.52962L13.5306 6.53025Z\" fill=\"currentColor\"><\/path>\n                <\/svg>\n            <\/button>\n        \n        <!-- CTA Button (desktop only) -->\n                    <div class=\"hidden md:block flex-shrink-0 \" x-show=\"showCtaButton\" x-transition:enter=\"transition ease-out duration-500 delay-500\" x-transition:enter-start=\"opacity-0 transform translate-x-8\" x-transition:enter-end=\"opacity-100 transform translate-x-0\">\n                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n            <\/div>\n        \n        <!-- Mobile Dropdown Menu -->\n                    <div class=\"absolute top-full z-20 w-full left-0 block md:hidden\" x-show=\"mobileSubMenuOpen\" x-collapse>\n                <div class=\"rounded-b-xl max-h-[calc(100dvh-80px)] overflow-y-auto bg-white shadow-lg\">\n                    <div class=\"py-10 px-5\">\n                        <ul x-ref=\"hiddenLinks\" class=\"hidden-links !m-0 !p-0 !list-none\">\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-gabaa-alternative\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        R\u00e9cepteurs GABAA\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nmda\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        R\u00e9cepteurs NMDA\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-de-glycine\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        R\u00e9cepteurs de la glycine\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/recepteurs-nicotiniques\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        R\u00e9cepteurs nicotiniques\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-trp\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Cha\u00eenes TRP\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-de-sodium\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Canaux sodiques\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-calciques\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Canaux calciques\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-potassiques\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Canaux potassiques\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/canaux-chlorure\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Canaux chlorure\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        TMEM175\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7fc3d43a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-fe91d411 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-7817b4e4cf0bfc57d55a986f4f5d6537\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">Classes cibles | Canaux ION<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-6aa6d1eb05cef37e644a3dd60f9a02b5\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">TMEM175<\/h1>\n\n\n\n<p>Sygnature Discovery acc\u00e9l\u00e8re la d\u00e9couverte de m\u00e9dicaments ciblant les canaux ioniques en combinant des mod\u00e8les cellulaires sur mesure avec une \u00e9lectrophysiologie robuste et un criblage \u00e0 haut d\u00e9bit valid\u00e9, vous permettant ainsi de faire progresser vos programmes TMEM175 en toute confiance.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d6b9ab57 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Syst\u00e8me d'automatisation de laboratoire configur\u00e9 pour les analyses de canaux ioniques, permettant un profilage et une caract\u00e9risation pr\u00e9cis dans la d\u00e9couverte de m\u00e9dicaments.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/ion-channel-assays-high-throughput-screening-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-66d2abdc3d3135e0f5f1dcde4cea1263\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">Soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group children-fill-width is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Faites progresser vos programmes de d\u00e9couverte de m\u00e9dicaments ciblant TMEM175 gr\u00e2ce \u00e0 notre plateforme d\u2019analyse valid\u00e9e. Nous fournissons des mod\u00e8les TMEM175 de type sauvage et des variants pertinents pour la maladie, compatibles avec le criblage \u00e0 haut d\u00e9bit, l\u2019\u00e9lectrophysiologie d\u00e9taill\u00e9e et le profilage pharmacologique, afin d\u2019acc\u00e9l\u00e9rer l\u2019innovation th\u00e9rapeutique. <\/h2>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">TMEM175 est un canal potassique lysosomal constitutif qui contribue \u00e0 la r\u00e9gulation du pH lysosomal, du potentiel membranaire et de l\u2019autophagie. Un dysfonctionnement de TMEM175 a \u00e9t\u00e9 associ\u00e9 \u00e0 l\u2019agr\u00e9gation de l\u2019alpha-synucl\u00e9ine et \u00e0 une diminution de l\u2019\u00e9limination des prot\u00e9ines, deux ph\u00e9nom\u00e8nes importants dans la maladie de Parkinson. Les variants codants \u00e0 perte et \u00e0 gain de fonction sont associ\u00e9s au risque de d\u00e9velopper la maladie, faisant de TMEM175 une cible prometteuse mais encore peu explor\u00e9e dans la recherche de m\u00e9dicaments ciblant les canaux ioniques. Notre plateforme TMEM175 est con\u00e7ue pour permettre l\u2019\u00e9laboration de strat\u00e9gies visant \u00e0 restaurer l\u2019hom\u00e9ostasie lysosomale et \u00e0 mieux comprendre la biologie des maladies neurod\u00e9g\u00e9n\u00e9ratives.   <\/p>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover has-aspect-ratio aspect-59x35 has-overlay absolute inset-0 w-full h-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"Laboratory setting with scientists reviewing data near an automated screening system, illustrating customized screening cascades for ion channel assay development and pharmacology workflows.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/customized-screening-cascades-ion-channel-assay-development-lab-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-57c5744afc22462a739553f3b110d7be\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">Acc\u00e9dez aux analyses dont vous avez besoin<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group children-fill-width is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">Sygnature Discovery propose des lign\u00e9es cellulaires propri\u00e9taires exprimant TMEM175, incluant les formes sauvages et variantes ainsi que des orthologues cl\u00e9s chez diff\u00e9rentes esp\u00e8ces. Nos mod\u00e8les cellulaires valid\u00e9s et nos plateformes d\u2019\u00e9lectrophysiologie vous aident \u00e0\u00a0: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Acc\u00e9l\u00e9rer l\u2019identification des cibles et l\u2019optimisation des prospects<\/li>\n\n\n\n<li>Explorer les effets fonctionnels des variants de TMEM175 pertinents pour la maladie<\/li>\n\n\n\n<li>Faire progresser en toute confiance les programmes de d\u00e9couverte de m\u00e9dicaments ciblant TMEM175<br><\/li>\n<\/ul>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">Besoin de quelque chose de sp\u00e9cifique\u00a0? Notre \u00e9quipe exp\u00e9riment\u00e9e <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/generation-de-lignees-cellulaires\/\">en g\u00e9n\u00e9ration de lign\u00e9es cellulaires<\/a> peut d\u00e9velopper et valider des variantes suppl\u00e9mentaires de TMEM175 pour soutenir vos recherches. <\/p>\n\n\n\n<div style=\"margin-top:var(--wp--preset--spacing--60)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"Tables pegasus-block relative\" x-data=\"{ tooltipOpen: false }\">\n  <div class=\"Tables_scroll overflow-x-auto w-full max-w-[80vw] sm:max-w-none\">\n                                                                                                                                    \n    <table class=\"Tables-table min-w-max table-auto overflow-hidden  Tables-padding-small\" style=\"--vertical-border-color: rgba(157, 175, 190, 0,2); --horizontal-border-color: rgba(157, 175, 190, 0,2); border-radius: 1.5rem; border: 1px solid rgba(0,0,0,0.1);\">\n      \n            <thead>\n        <tr>\n                      <th colspan=\"3\" class=\"Tables-header \" style=\"\">\n              <div class=\"has-text-xl-font-size font-medium text-white text-left sm:text-center\">\n                Off-the-Shelf TMEM175 Assays\n              <\/div>\n            <\/th>\n                  <\/tr>\n      <\/thead>\n      \n      <tbody>\n                                                      <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (humain)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (LoF)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (GoF)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (souris)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (rat)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (chien)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>TMEM175 (singe)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                                                  \n                \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                \n                \n                <td class=\"Tables-cell\" style=\"min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                        <\/tbody>\n\n    <\/table>\n  <\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-cbe57604 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--100)\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Progress Progress--left Progress--scroll absolute z-[1000]\" style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--dark-blue-600); --progress-background: rgba(0, 50, 82, 0.2);\" x-data=\"progress()\" x-init='init({\"position\":\"left\",\"eventType\":\"scroll\",\"scrollOptions\":{\"scroll_target\":\"m\\u00e8re\",\"container_selector\":\"\"},\"tickerOptions\":[],\"formOptions\":[],\"anchorPoints\":{\"align_points\":true,\"points\":[{\"element_id\":\"\\u00e9l\\u00e9ment-collant-1\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-2\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-3\",\"label\":\"\"}]},\"showEndDot\":true,\"containerScrollOffset\":0.2,\"progressThreshold\":0.005})' x-cloak data-position=\"left\" data-event-type=\"scroll\">\n    <div class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\" x-ref=\"fill\"><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d2c5c54a wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">\u00c9tudier en d\u00e9tail la biologie de TMEM175<\/h2>\n\n\n\n<p>Notre plateforme TMEM175 vous offre les outils n\u00e9cessaires pour explorer la biologie et acc\u00e9l\u00e9rer les d\u00e9couvertes gr\u00e2ce \u00e0 un flux de travail int\u00e9gr\u00e9. Vous pouvez\u00a0: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u00c9valuer l\u2019activation en conditions d\u2019acidification extracellulaire<\/li>\n\n\n\n<li>\u00c9valuer les r\u00e9ponses pharmacologiques sp\u00e9cifiques \u00e0 chaque variante<\/li>\n\n\n\n<li>Mesurer l\u2019efficacit\u00e9 des compos\u00e9s en fonction des facteurs g\u00e9n\u00e9tiques pertinents pour la maladie<br> arri\u00e8re-plans<\/li>\n\n\n\n<li>Acc\u00e9dez aux orthologues d\u2019esp\u00e8ces et aux lign\u00e9es cellulaires pertinentes pour la maladie<\/li>\n\n\n\n<li>R\u00e9aliser des exp\u00e9riences d\u2019\u00e9lectrophysiologie robustes et des analyses \u00e0 haut d\u00e9bit valid\u00e9es<br> tests de d\u00e9pistage<\/li>\n<\/ul>\n\n\n\n<p>En comparant c\u00f4te \u00e0 c\u00f4te les variants de type sauvage, de perte de fonction et de gain de fonction, vous pouvez d\u00e9couvrir comment la diversit\u00e9 g\u00e9n\u00e9tique fa\u00e7onne l\u2019activit\u00e9 de TMEM175 et identifier de nouvelles fa\u00e7ons de moduler le canal.<\/p>\n\n\n\n<p>Notre plateforme valid\u00e9e d\u00e9tecte les changements fonctionnels subtils des variants de TMEM175 et quantifie l\u2019activit\u00e9 du modulateur, permettant ainsi la d\u00e9couverte d\u2019outils pour r\u00e9tablir l\u2019\u00e9quilibre lysosomal et faire progresser la recherche sur les maladies neurod\u00e9g\u00e9n\u00e9ratives.<\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-2\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">\u00c9lectrophysiologie SSM des canaux ioniques lysosomaux<\/h2>\n\n\n\n<p>En compl\u00e9ment de nos capacit\u00e9s de patch-clamp automatis\u00e9es, nous proposons \u00e9galement l\u2019\u00e9lectrophysiologie sur membrane support\u00e9e solide, une approche efficace pour les canaux lysosomaux intracellulaires tels que TMEM175. Ceci permet la reconstitution de membranes lysosomales contenant TMEM175, l\u2019\u00e9valuation d\u2019activateurs et d\u2019inhibiteurs au format 96 puits, et une validation orthogonale pour \u00e9tayer les r\u00e9sultats du criblage et confirmer la modulation des canaux ioniques organellaires. <\/p>\n<\/div>\n\n\n<section class=\"Pegasus__Container w-full hidden sm:block  relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100)\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":true,\"element\":\"autre\",\"elementId\":\"\\u00e9l\\u00e9ment-collant-1\",\"action\":\"vue\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   border-color:#FFFFFF;border-radius:9px;border-width:10px;\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-000-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/tmem175-dcpib-dose-response-electrophysiology-traces-300x116.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/tmem175-dcpib-dose-response-electrophysiology-traces.webp 550w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"550\" height=\"213\" class=\"image-original \" alt=\"Electrophysiology traces showing TMEM175 channel currents before and during increasing concentrations of the agonist DCPIB, illustrating activation profiles for lysosomal ion channel characterization.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/tmem175-dcpib-dose-response-electrophysiology-traces.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/tmem175-dcpib-dose-response-electrophysiology-traces-300x116.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/tmem175-dcpib-dose-response-electrophysiology-traces.webp 550w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n<p class=\"has-text-sm-font-size\" style=\"padding-top:var(--wp--preset--spacing--10)\">Trac\u00e9s de courant repr\u00e9sentatifs de TMEM175 avant (ligne grise) et pendant la pr\u00e9sence de concentrations croissantes de l\u2019agoniste DCPIB (lignes bleues). Les courants sont induits par une rampe de 500 ms de -80 mV \u00e0 +80 mV, suivie d\u2019un palier de 500 ms de -80 mV \u00e0 +80 mV avant un retour au potentiel de maintien de 0 mV. <\/p>\n\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n\n\n<div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":false,\"element\":\"autre\",\"elementId\":\"\\u00e9l\\u00e9ment-collant-2\",\"action\":\"vue\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-300x211.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib.webp 712w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-513x360.webp 513w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-640x449.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"712\" height=\"500\" class=\"image-original \" alt=\"Graph showing TMEM175 current traces measured using solid-supported membrane electrophysiology in the presence of increasing concentrations of DCPIB, illustrating lysosomal ion channel modulation.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-300x211.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib.webp 712w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-513x360.webp 513w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/TMEM175_ssm_traces_surfe2r_dcpib-640x449.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n\n\n<p class=\"has-text-sm-font-size\" style=\"padding-top:var(--wp--preset--spacing--10)\">Trac\u00e9s de courant repr\u00e9sentatifs TMEM175 mesur\u00e9s en pr\u00e9sence de concentrations croissantes de l\u2019agoniste DCPIB (0,3-30 \u00b5M) \u00e0 l\u2019aide d\u2019une plateforme d\u2019\u00e9lectrophysiologie \u00e0 membrane support\u00e9e solide (SSM).<\/p>\n\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-5 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"561\" height=\"588\" class=\"image-original \" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTYxIiBoZWlnaHQ9IjU4OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit overflow-hidden text-content-dark mobile-stacking-standard   left-aligned-multi-slide-carousel is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--50); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section x-data='newcarousel({\"transition\":\"slide\",\"overflow\":true,\"autoplay\":0,\"infinite\":false,\"preview\":false,\"slidesInView\":1.75,\"slidesInViewTablet\":1,\"slidesInViewMobile\":1.15,\"slideGap\":0,\"align\":\"left\",\"swipeScroll\":false,\"snapToSlides\":false})' x-intersect.once=\"initAutoplay()\" class=\"Content__Carousel wp-elements-3dedbad514473664ee4d9166738c001a relative h-full\" style=\"--slides-to-show-desktop: 1.75; --slides-to-show-tablet: 1; --slides-to-show-mobile: 1.15; --slide-gap: 0px; --carousel-arrow-spacing: 50%; --carousel-arrow-inset: 0rem; padding-top:0;padding-bottom:var(--wp--preset--spacing--60);;\">\n            \n    <div class=\"Carousel__WrapperOuter relative z-10\" data-carousel-anchor style=\"--carousel-arrow-spacing: %; --carousel-arrow-inset: rem\">\n\n                    <div class=\"pb-10 intro-text-wrapper\">\n                <div class=\"flex flex-col md:flex-row relative\">\n                    <div class=\"Carousel__introText mb-16 md:mb-0 w-full md:w-[45%] text-left md:max-w-[708px]\">\n                        <p class=\"has-text-align-center is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style\" style=\"padding-bottom: var(--wp--preset--spacing--30); color: rgba(0, 16, 36, 0.7); padding-right: 0px; padding-left: 0px; font-style: normal; font-weight: 600; letter-spacing: 0.96px; --paragraph-dot-color: #005de5; text-align: left;\">\u00c9tudes de cas<\/p>\n<h2 class=\"heading-two wp-block-heading has-text-4-xl-font-size\">Approuv\u00e9 par des clients du monde entier<\/h2>\n<p>Nos clients nous disent que nous agissons comme un prolongement de leur \u00e9quipe et que nous leur apportons une expertise de haut niveau \u00e0 chaque \u00e9tape du processus de d\u00e9couverte de m\u00e9dicaments. Que nous vous accompagnions tout au long du processus ou seulement sur une partie, notre objectif n\u2019est pas simplement de vous faire passer \u00e0 l\u2019\u00e9tape suivante, mais de jeter les bases d\u2019un m\u00e9dicament commercialis\u00e9 avec succ\u00e8s. <\/p>\n\n                    <\/div>\n                                    <\/div>\n            <\/div>\n            \n        <div x-ref=\"sliderContainer\" class=\"Carousel__Container h-full show-overflow\">\n        <div class=\"Carousel__Wrapper   Carousel--snap-scroll Carousel--snap-left \" style=\"padding-top:0;padding-bottom:var(--wp--preset--spacing--60);;\">\n            <div class=\"Carousel\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-2d9db6af00b70626cb39c8cbd19ab2f6\" style=\"font-style:normal;font-weight:500\">De la prise de contact \u00e0 la pr\u00e9-nomination des candidats en 18 mois  <\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-e0aab337ded968a4ea9a439c552f5afa\">En passant de la phase de s\u00e9lection \u00e0 la nomination de pr\u00e9-candidat en moins de la moiti\u00e9 du d\u00e9lai standard du secteur, ce programme d\u00e9montre comment des \u00e9quipes scientifiques connect\u00e9es et des informations en temps r\u00e9el peuvent acc\u00e9l\u00e9rer les d\u00e9couvertes complexes.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--6\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/storm-therapeutics-from-lead-to-pre-candidate-nomination-in-18-months\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.webp 600w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-469x360.webp 469w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"600\" height=\"461\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"STORM Therapeutics logo featuring a stylized DNA helix and gradient background\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNjAwIiBoZWlnaHQ9IjQ2MSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.webp 600w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-469x360.webp 469w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-b3d2fcb4c215eda5e0b576b58fb7dce5\" style=\"font-style:normal;font-weight:500\">Sitryx : Donner vie aux nouvelles id\u00e9es<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-47653e2d0a82108f47008efbf0d1df7d\">De nombreux programmes de recherche de m\u00e9dicaments prometteurs voient le jour au sein de jeunes entreprises de biotechnologie. Pourtant, \u00e0 leurs d\u00e9buts, ces nouvelles organisations disposent rarement des ressources ou des infrastructures de laboratoire n\u00e9cessaires pour transformer imm\u00e9diatement leurs id\u00e9es novatrices en un nouveau m\u00e9dicament. <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--7\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/sitryx-empowering-new-ideas-2\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-8f5dae3bf4ede09e581e582784ac22e9\" style=\"font-style:normal;font-weight:500\">Cr\u00e9ation rapide d\u2019id\u00e9es gr\u00e2ce \u00e0 l\u2019IA g\u00e9n\u00e9rative (GenAI) avec Iktos Makya<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-7cd6cbe0d998822428c1c1ddbbf96bdb\">Les principaux algorithmes <a href=\"\/drug-discovery\/computer-aided-drug-design\/artificial-intelligence-ai\/\"><strong>d\u2019intelligence artificielle<\/strong><\/a> g\u00e9n\u00e9rative (GenAI) pour la conception <em>de novo<\/em> sont utilis\u00e9s de mani\u00e8re routini\u00e8re dans nos programmes de chimie m\u00e9dicinale pour permettre une g\u00e9n\u00e9ration rapide d\u2019id\u00e9es afin d\u2019atteindre les objectifs du projet.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--8\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/rapid-creation-of-ideas-using-generative-ai-genai-with-iktos-makya\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-d0460f53a4ac9daf7767812b0402b7d9\" style=\"font-style:normal;font-weight:500\">Corcept Therapeutics : Collaboration int\u00e9gr\u00e9e en mati\u00e8re de d\u00e9couverte de m\u00e9dicaments<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-0507f9fe29a19aef2cfafcb9851d28eb\">Corcept Therapeutics, situ\u00e9e \u00e0 Menlo Park, en Californie, est un chef de file dans la d\u00e9couverte et le d\u00e9veloppement de m\u00e9dicaments qui r\u00e9gulent les effets du cortisol.  <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--9\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/corcept-therapeutics-integrated-drug-discovery-collaboration\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-b2e7fb3b48d59c1c0a1e4af5911cd8f0\" style=\"font-style:normal;font-weight:500\">Campagne d\u2019optimisation des leads CellCentric \u2013 CCS1477<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-3bba5e28bf9359510668296271677c81\">CellCentric d\u00e9veloppe de nouveaux traitements contre le cancer en s\u2019appuyant sur sa compr\u00e9hension de l\u2019\u00e9pig\u00e9n\u00e9tique.  <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--10\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/cellcentric-lead-optimisation-campaign\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-e907cedde045f1eeeb26ed9340006da1\" style=\"font-style:normal;font-weight:500\">D\u00e9couverte de cibles \u00e9pig\u00e9n\u00e9tiques par criblage de fragments, ciblant BRD3.<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-27cee9809d96fc20c4fa6dfddd921d44\">La d\u00e9couverte de m\u00e9dicaments bas\u00e9e sur des fragments permet d\u2019explorer un large \u00e9ventail de l\u2019espace chimique gr\u00e2ce \u00e0 une biblioth\u00e8que relativement restreinte mais diversifi\u00e9e de petites mol\u00e9cules.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--11\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/fragment-based-hit-discovery-for-the-epigenetic-target-brd3\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-ivory-000-background-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-c331df6226ab72dc1083938b26c7a581\" style=\"font-style:normal;font-weight:500\">Identification de 3 compos\u00e9s actifs en phase clinique et de 6 candidats au d\u00e9veloppement<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-2a49c5ce524b34a8c2c8f1a72b4f5bc9\">Soci\u00e9t\u00e9 britannique de d\u00e9couverte de m\u00e9dicaments \u00e0 petites mol\u00e9cules<\/p>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-859e1996edaa09783335ee8ebafcdae9\">Il convient de se concentrer sur l\u2019identification de nouveaux traitements pour les maladies respiratoires inflammatoires, telles que la BPCO.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--12\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/hit-identification-to-3-compounds-in-the-clinic-and-6-development-candidates\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    \n\t\t\t\t\n\t\t\t\t\n                <\/div>\n    <\/section>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--70); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">    <section class=\"FeaturedPostGrid\">\n        <div class=\"container\">\n            <p class=\"text-center\">No featured post selected.<\/p>\n        <\/div>\n    <\/section>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-13 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Capacit\u00e9s connexes<\/h2>\n\n\n\n<p>Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d\u2019experts exp\u00e9riment\u00e9s de l\u2019industrie pharmaceutique du monde entier, garantissant l\u2019excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/ion-channels-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/ion-channels.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Ion channels\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/ion-channels.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/ion-channels-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/ion-channels.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-1abc7e94ca6001d827a56224eec58f6f\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/\">canaux ioniques<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e23fd27890c19bd2081272bdd6878493\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Des tests complets sur les canaux ioniques et des lign\u00e9es cellulaires sur mesure permettent un criblage haute fid\u00e9lit\u00e9 et des informations sur la s\u00e9curit\u00e9, acc\u00e9l\u00e9rant ainsi le passage de la d\u00e9couverte de compos\u00e9s prometteurs \u00e0 l\u2019optimisation.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/cell-line-generation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/cell-line-generation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Cell line generation\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/cell-line-generation.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/cell-line-generation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/cell-line-generation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-d8d2b118b539d3763f03ecab2bddfda2\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/generation-de-lignees-cellulaires\/\">g\u00e9n\u00e9ration de lign\u00e9es cellulaires<\/a><\/h3>\n\n\n\n<p>Lign\u00e9es cellulaires stables personnalis\u00e9es avec une expression robuste et une reproductibilit\u00e9 des tests, une conception et une validation simplifi\u00e9es pour des flux de travail de d\u00e9couverte de m\u00e9dicaments fiables.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/generation-de-lignees-cellulaires\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/electrophysiology-2-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/electrophysiology-2.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Electrophysiology\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/electrophysiology-2.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/electrophysiology-2-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/electrophysiology-2.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-b43568f771f51e3e29d2ebcc5fe77db5\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/electrophysiologie\/\">\u00c9lectrophysiologie<\/a><\/h3>\n\n\n\n<p>Des informations pr\u00e9cises sur les canaux ioniques et les transporteurs gr\u00e2ce \u00e0 des \u00e9tudes \u00e9lectrophysiologiques sur mesure, permettant la validation des cibles, l\u2019identification des mol\u00e9cules actives et l\u2019optimisation des compos\u00e9s candidats.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/electrophysiologie\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"High Throughput Screening\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-ee47efcfe0922214ae246b4562f55da1\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">criblage \u00e0 haut d\u00e9bit<\/a><\/h3>\n\n\n\n<p>Identification int\u00e9gr\u00e9e de cibles th\u00e9rapeutiques utilisant le criblage \u00e0 haut d\u00e9bit, le criblage de fragments et une automatisation avanc\u00e9e, fournissant des points de d\u00e9part de haute qualit\u00e9 pour une d\u00e9couverte de m\u00e9dicaments r\u00e9ussie.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":7805,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-8815","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TMEM175 - Sygnature<\/title>\n<meta name=\"description\" content=\"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#039;optimisation de compos\u00e9s candidats.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TMEM175 - Sygnature\" \/>\n<meta property=\"og:description\" content=\"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#039;optimisation de compos\u00e9s candidats.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/\" \/>\n<meta property=\"og:site_name\" content=\"Sygnature\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-27T15:13:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/sygnature-hit-to-lead-team-collaboration-scaled.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimation du temps de lecture\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/\",\"name\":\"TMEM175 - Sygnature\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\"},\"datePublished\":\"2025-12-12T11:26:07+00:00\",\"dateModified\":\"2026-01-27T15:13:23+00:00\",\"description\":\"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#39;optimisation de compos\u00e9s candidats.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/#breadcrumb\"},\"inLanguage\":\"fr-CA\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/tmem175\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/page-daccueil\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Classes cibles\",\"item\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"canaux ioniques\",\"item\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/classes-cibles\\\/canaux-ioniques\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"TMEM175\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#website\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"name\":\"Sygnature Discovery\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\"},\"alternateName\":\"Sygnature\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-CA\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#organization\",\"name\":\"Sygnature\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-CA\",\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"contentUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/Logo.svg\",\"width\":1,\"height\":1,\"caption\":\"Sygnature\"},\"image\":{\"@id\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"TMEM175 - Sygnature","description":"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#39;optimisation de compos\u00e9s candidats.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/","og_locale":"fr_CA","og_type":"article","og_title":"TMEM175 - Sygnature","og_description":"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#39;optimisation de compos\u00e9s candidats.","og_url":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/","og_site_name":"Sygnature","article_modified_time":"2026-01-27T15:13:23+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/sygnature-hit-to-lead-team-collaboration-scaled.webp","type":"image\/webp"}],"twitter_card":"summary_large_image","twitter_misc":{"Estimation du temps de lecture":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/","url":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/","name":"TMEM175 - Sygnature","isPartOf":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website"},"datePublished":"2025-12-12T11:26:07+00:00","dateModified":"2026-01-27T15:13:23+00:00","description":"Acc\u00e9dez aux services experts de criblage et de profilage des canaux ioniques TMEM175 chez Sygnature Discovery, pour soutenir vos efforts de d\u00e9couverte de m\u00e9dicaments et d&#39;optimisation de compos\u00e9s candidats.","breadcrumb":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/#breadcrumb"},"inLanguage":"fr-CA","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/tmem175\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.sygnaturediscovery.com\/fr\/page-daccueil\/"},{"@type":"ListItem","position":2,"name":"Classes cibles","item":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/"},{"@type":"ListItem","position":3,"name":"canaux ioniques","item":"https:\/\/www.sygnaturediscovery.com\/fr\/classes-cibles\/canaux-ioniques\/"},{"@type":"ListItem","position":4,"name":"TMEM175"}]},{"@type":"WebSite","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#website","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","name":"Sygnature Discovery","description":"","publisher":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization"},"alternateName":"Sygnature","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.sygnaturediscovery.com\/fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-CA"},{"@type":"Organization","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#organization","name":"Sygnature","url":"https:\/\/www.sygnaturediscovery.com\/fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-CA","@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/","url":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","contentUrl":"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Logo.svg","width":1,"height":1,"caption":"Sygnature"},"image":{"@id":"https:\/\/www.sygnaturediscovery.com\/fr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/pages\/8815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/comments?post=8815"}],"version-history":[{"count":0,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/pages\/8815\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/pages\/7805"}],"wp:attachment":[{"href":"https:\/\/www.sygnaturediscovery.com\/fr\/wp-json\/wp\/v2\/media?parent=8815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}