{"id":7661,"date":"2025-12-11T08:29:45","date_gmt":"2025-12-11T08:29:45","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/decouverte-integree-de-medicaments\/decouverte-de-medicaments-basee-sur-des-fragments\/"},"modified":"2026-02-06T15:26:32","modified_gmt":"2026-02-06T15:26:32","slug":"decouverte-de-medicaments-basee-sur-des-fragments","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/decouverte-de-medicaments-basee-sur-des-fragments\/","title":{"rendered":"D\u00e9couverte de m\u00e9dicaments bas\u00e9e sur les fragments"},"content":{"rendered":"\n<div x-data='subNav({&quot;anchor_map&quot;:{&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/decouverte-integree-de-medicaments\\\/identification-et-validation-de-la-cible\\\/&quot;:&quot;Identification et validation des cibles&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/decouverte-integree-de-medicaments\\\/identification-des-impacts\\\/&quot;:&quot;Identification des impacts&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/decouverte-integree-de-medicaments\\\/hit-to-lead\\\/&quot;:&quot;Hit-to-Lead&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/decouverte-integree-de-medicaments\\\/lead-optimisation\\\/&quot;:&quot;Optimisation des prospects&quot;}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" @click.away=\"mobileSubMenuOpen = false\" x-cloak style=\"\">\n    <div x-ref=\"fixedNav\"\n        class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/\" \n                                                                class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">D\u00e9couverte int\u00e9gr\u00e9e de m\u00e9dicaments<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/identification-et-validation-de-la-cible\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/identification-et-validation-de-la-cible\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/identification-et-validation-de-la-cible\/' === window.location.href ? 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<\/div>\n<\/div><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7fc3d43a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-fe91d411 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-7adddb813c14566e9dc5d78cde8bca41\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">Solutions scientifiques | Identification des hits<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-5ca36349ad8a94ee835a3599f805f463\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">D\u00e9couverte de m\u00e9dicaments bas\u00e9e sur les fragments<\/h1>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-999df46610deee7d2e978b297631d093\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Des points de d\u00e9part de haute qualit\u00e9 aux pistes optimis\u00e9es, nous combinons le criblage de fragments, la biologie structurale, la chimie computationnelle et la chimie m\u00e9dicinale pour faire progresser votre programme.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-90bb52c3aac24bb379a087a134687390\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\"><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link 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srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Sygnature laboratory setting handling a microplate, demonstrating hit identification process in drug discovery.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/sygnature-hit-identification-drug-discovery-640x427.webp 640w\"><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--100); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-66d2abdc3d3135e0f5f1dcde4cea1263\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">Soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">La d\u00e9couverte de m\u00e9dicaments \u00e0 l&rsquo;aide de biblioth\u00e8ques de fragments de petites mol\u00e9cules dont le poids mol\u00e9culaire est g\u00e9n\u00e9ralement \u2264 300 Da offre une voie efficace pour l&rsquo;identification de cibles biologiques parmi un large \u00e9ventail de cibles.<\/h2>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">La plateforme de criblage de fragments de Sygnature Discovery est con\u00e7ue pour vous aider \u00e0 identifier des points de d\u00e9part de haute qualit\u00e9 et \u00e0 les d\u00e9velopper avec assurance. Nous combinons une biblioth\u00e8que de fragments sp\u00e9cialement con\u00e7ue avec des approches int\u00e9gr\u00e9es de biophysique, de biologie structurale, de chimie computationnelle et de chimie afin d&rsquo;adapter chaque campagne \u00e0 votre cible, \u00e0 votre biologie et aux objectifs de votre programme. <\/p>\n\n\n\n<p>Notre biblioth\u00e8que de fragments interne a \u00e9t\u00e9 soigneusement con\u00e7ue pour maximiser les chances d&rsquo;identifier des mol\u00e9cules actives. Elle est optimis\u00e9e pour une couverture optimale de l&rsquo;espace chimique et de la forme, et les fragments sont s\u00e9lectionn\u00e9s pour leur forte \u00ab\u00a0sociabilit\u00e9\u00a0\u00bb afin de faciliter le d\u00e9veloppement de nouvelles mol\u00e9cules par chimie. Les ajouts r\u00e9cents \u00e0 la biblioth\u00e8que ont \u00e9t\u00e9 int\u00e9gr\u00e9s \u00e0 des cibles th\u00e9rapeutiques et \u00e9valu\u00e9s par apprentissage automatique sur un panel de 50 cibles th\u00e9rapeutiques diverses afin de garantir leur pertinence pratique.  <br\/><\/p>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\"><br\/>Gr\u00e2ce \u00e0 une solide exp\u00e9rience des technologies de criblage de fragments compl\u00e9mentaires, nos \u00e9quipes appliquent r\u00e9guli\u00e8rement la conception de dispositifs \u00e0 base de fragments (FBDD) \u00e0 des cibles exigeantes telles que les prot\u00e9ines de liaison aux nucl\u00e9otides et les programmes de colle mol\u00e9culaire. D\u00e8s la strat\u00e9gie de criblage initiale <\/p>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media original has-overlay shrink-0\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-300x150.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-768x384.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem.webp 903w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-640x320.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"903\" height=\"452\" class=\"image-original \" alt=\"Diagram showing Sygnature Discovery's digital drug discovery ecosystem, illustrating data types and opportunities across drug discovery, preclinical, clinical and drug repurposing stages.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-300x150.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-768x384.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem.webp 903w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/bioinformatics-drug-discovery-data-ecosystem-640x320.webp 640w\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-cbe57604 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--100)\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div\n    class=\"Progress Progress--left Progress--scroll absolute z-[1000]\"\n    style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--ivory-300); --progress-background: rgba(249, 242, 232, 0.2);\"            x-data=\"progress()\"\n        x-init=\"init({&quot;position&quot;:&quot;left&quot;,&quot;eventType&quot;:&quot;scroll&quot;,&quot;scrollOptions&quot;:{&quot;scroll_target&quot;:&quot;m\\u00e8re&quot;,&quot;container_selector&quot;:&quot;&quot;},&quot;tickerOptions&quot;:[],&quot;formOptions&quot;:[],&quot;anchorPoints&quot;:{&quot;align_points&quot;:true,&quot;points&quot;:[{&quot;element_id&quot;:&quot;notre mission&quot;,&quot;label&quot;:&quot;&quot;},{&quot;element_id&quot;:&quot;pourquoi-choisir-sygnature&quot;,&quot;label&quot;:&quot;&quot;}]},&quot;showEndDot&quot;:true,&quot;containerScrollOffset&quot;:0.2,&quot;progressThreshold&quot;:0.005})\"\n        x-cloak\n        data-position=\"left\"\n    data-event-type=\"scroll\"\n>\n    <div\n        class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div\n            class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\"  x-ref=\"fill\"        ><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d2c5c54a wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"our-mission\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Notre biblioth\u00e8que de fragments de romans<\/h2>\n\n\n\n<p>La biblioth\u00e8que de fragments interne de Sygnature est con\u00e7ue pour fournir des cibles facilement exploitables et simples \u00e0 faire \u00e9voluer. Nos fragments optimis\u00e9s pr\u00e9sentent des points de diversit\u00e9 clairement d\u00e9finis pour la d\u00e9rivatisation, et la collection contient de petits ensembles d&rsquo;analogues autour de groupes fonctionnels cl\u00e9s afin de permettre une exploration rapide des relations structure-activit\u00e9 (RSA) pr\u00e9coces. Les liens structuraux entre la collection de fragments, la biblioth\u00e8que Sygnature Lead Finder et des ensembles commerciaux s\u00e9lectionn\u00e9s soutiennent l&rsquo;approche RSA par catalogue, maintenant ainsi une dynamique \u00e9lev\u00e9e apr\u00e8s l&rsquo;identification des fragments actifs.  <\/p>\n<\/div>\n\n\n\n<div id=\"why-choose-sygnature\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-xl-font-size\" style=\"font-style:normal;font-weight:300\">Structure hi\u00e9rarchis\u00e9e pour soutenir diff\u00e9rents parcours de d\u00e9pistage<\/h2>\n\n\n\n<p>La biblioth\u00e8que est organis\u00e9e en deux niveaux afin de mieux permettre une vari\u00e9t\u00e9 d&rsquo;approches de FBDD\u00a0:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Le niveau 1 est la biblioth\u00e8que compl\u00e8te pour le criblage biophysique \u00e0 haut d\u00e9bit, offrant une diversit\u00e9 maximale<\/li>\n\n\n\n<li>Le niveau 2 est constitu\u00e9 de sous-decks s\u00e9lectionn\u00e9s parmi les donn\u00e9es du niveau 1, format\u00e9s pour prendre en charge des m\u00e9thodologies \u00e0 plus faible d\u00e9bit, offrant soit une sensibilit\u00e9 accrue, soit une activation structurelle directe.<\/li>\n\n\n\n<li>Un ensemble de fragments covalents compl\u00e9mentaires est \u00e9galement disponible.<\/li>\n<\/ul>\n<\/div>\n\n\n\n<div id=\"sticky-section-3\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-xl-font-size\" style=\"font-style:normal;font-weight:300\">Flexibilit\u00e9 int\u00e9gr\u00e9e pour votre programme<\/h2>\n\n\n\n<p>Cette approche par \u00e9tapes vous permet d&rsquo;adapter la recherche de cibles \u00e0 votre biologie cible et aux plateformes disponibles. Les flux de travail typiques comprennent\u00a0: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Analyse biophysique de liaison \u00e0 haut d\u00e9bit, suivie d&rsquo;une confirmation par CRX ou RMN<\/li>\n\n\n\n<li>Criblage par XRC ou RMN, suivi d&rsquo;une d\u00e9termination d&rsquo;affinit\u00e9 par une technologie telle que SPR, SpS ou MST<\/li>\n<\/ul>\n\n\n\n<p>Cette flexibilit\u00e9 permet de prioriser des \u00e9l\u00e9ments tels que la diversit\u00e9 ou l&rsquo;activation structurelle imm\u00e9diate, et d&rsquo;appliquer le type d&rsquo;analyse le plus appropri\u00e9 \u00e0 chaque cible.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100)\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data=\"reveal({&quot;initiallyVisible&quot;:true,&quot;element&quot;:&quot;autre&quot;,&quot;elementId&quot;:&quot;notre mission&quot;,&quot;action&quot;:&quot;vue&quot;})\" styles=\";\">\n\t        \n    \t\t<div x-show=\"show\"\n\t\t\tx-transition:enter=\"transition ease-out duration-500\"\n\t\t\tx-transition:enter-start=\"opacity-0\"\n\t\t\tx-transition:enter-end=\"opacity-100\"\n\t\t\tx-transition:leave=\"transition ease-in duration-500 absolute inset-0\"\n\t\t\tx-transition:leave-start=\"opacity-100\"\n\t\t\tx-transition:leave-end=\"opacity-0\"\n\t\t\tx-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"1500\" height=\"1000\" class=\"image-original \" alt=\"Plaque multipuits utilis\u00e9e pour le criblage \u00e0 haut d\u00e9bit de fragments dans la d\u00e9couverte de m\u00e9dicaments bas\u00e9e sur les fragments\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/fragment-based-drug-discovery-screening-640x427.webp 640w\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"561\" height=\"588\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   carousel-gap-1xs is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--100); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section x-data=\"newcarousel({&quot;transition&quot;:&quot;slide&quot;,&quot;overflow&quot;:false,&quot;autoplay&quot;:0,&quot;infinite&quot;:false,&quot;preview&quot;:false,&quot;slidesInView&quot;:3,&quot;slidesInViewTablet&quot;:2,&quot;slidesInViewMobile&quot;:1.15,&quot;slideGap&quot;:0,&quot;align&quot;:&quot;left&quot;,&quot;swipeScroll&quot;:false,&quot;snapToSlides&quot;:false})\" x-intersect.once=\"initAutoplay()\"         class=\"Content__Carousel carousel-gap-1xs wp-elements-db0b75649fb477ee5c858d4507151f50 relative h-full\"\n         style=\"--slides-to-show-desktop: 3; --slides-to-show-tablet: 2; --slides-to-show-mobile: 1.15; --slide-gap: 0px; --carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem;\">\n            \n    <div class=\"Carousel__WrapperOuter relative z-10\"\n        data-carousel-anchor \n        style=\"--carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem\">\n\n                    <div class=\"pb-10 intro-text-wrapper\">\n                <div class=\"flex flex-col md:flex-row relative\">\n                    <div class=\"Carousel__introText mb-16 md:mb-0 w-full md:w-[45%] text-left md:max-w-[708px]\">\n                        <p class=\"has-text-4-xl-font-size has-text-3-xl-font-size\">Flux de travail de s\u00e9lection des fragments<\/p>\n<p>Nous fournissons des r\u00e9sultats de haute qualit\u00e9 gr\u00e2ce \u00e0 un flux de travail robuste et enti\u00e8rement tra\u00e7able qui relie technologies, biblioth\u00e8ques et expertises. Chaque \u00e9tape est int\u00e9gr\u00e9e pour une visibilit\u00e9 optimale du d\u00e9but \u00e0 la fin, permettant des programmes FBDD efficaces et une progression r\u00e9solue des projets. <\/p>\n\n                    <\/div>\n                                            <div class=\"Navigation__Arrows container md:absolute alignment vertical-top horizontal-right \" style=\"--carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem\">\n                                                    <button x-on:click=\"previousSlide()\" \n                                    class=\"Navigation__Arrows--prev flex items-center justify-center w-10 h-10 rounded-full p-2 transition-opacity duration-500\"\n                                    :class=\"firstSlide ? 'opacity-50 pointer-events-none' : 'opacity-100'\"\n                                    style=\"background-color:var(--wp--preset--color--blue-300);\">\n                                <span class=\"sr-only\">Previous Slide<\/span>\n                                <svg width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path d=\"M22.8047 14.6992L6.60438 14.6992\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n                                    <path d=\"M14.7031 22.8008L6.60297 14.7006L14.7031 6.60048\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n                                <\/svg>\n                            <\/button>\n                        \n                                                    <button x-on:click=\"nextSlide()\" \n                                    class=\"Navigation__Arrows--next flex items-center justify-center w-10 h-10 rounded-full p-2 transition-opacity duration-500\" \n                                    :class=\"lastSlide ? 'opacity-50 pointer-events-none' : 'opacity-100'\"\n                                    style=\"background-color:var(--wp--preset--color--blue-300);\">\n                                <span class=\"sr-only\">Next Slide<\/span>\n                                <svg width=\"28\" height=\"28\" viewbox=\"0 0 28 28\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path d=\"M5.92188 14.0264H22.1222\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n                                    <path d=\"M14.0234 5.92871L22.1236 14.0289L14.0234 22.129\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"\/>\n                                <\/svg>\n                            <\/button>\n                        \n                        <\/div>\n                                    <\/div>\n            <\/div>\n            \n        <div x-ref=\"sliderContainer\" class=\"Carousel__Container h-full \">\n        <div class=\"Carousel__Wrapper overflow-hidden  Carousel--snap-scroll Carousel--snap-left \" style=\"\">\n            <div class=\"Carousel\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-c03dffef791fab723a3a94fd064d215a\" style=\"font-style:normal;font-weight:400\">D\u00e9veloppement du test et \u00e9tude pilote<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-a9ef65bb45919513906ebf1e31efdab9\">Identifier la concentration de d\u00e9pistage et<br\/> Taux de r\u00e9ussite potentiel.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-2480075b0f550b219aede6cfae212681\" style=\"font-style:normal;font-weight:400\">\u00c9cran principal<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-f58bc3c596c499e79a7411f57d6419a1\">S\u00e9lectionnez la liste des r\u00e9sultats initiaux<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-e5b3d1702c175c219c1b11977598f790\" style=\"font-style:normal;font-weight:400\">D\u00e9termination de l&rsquo;affinit\u00e9<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-1e83d274b964c1bcc5796b98305c9938\">Analyser le comportement de liaison et<br\/> puissance en profondeur.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-bd2efaee18631155766d670c3c355263\" style=\"font-style:normal;font-weight:400\">Hit-rebuy + Analogues Closer<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"\/>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-454c8c32946f1359a33d7cb4e19c7a4d\" style=\"font-style:normal;font-weight:400\">Confirmation de coup\/D\u00e9termination d&rsquo;affinit\u00e9<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-1dfeee042032f6468d5cfc9f0d2bcc9e\">Analyse SAR rapide et confirmation des r\u00e9sultats, y compris des tests orthogonaux si n\u00e9cessaire.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-f2b56838ff06b74e00461419bde2c003\" style=\"font-style:normal;font-weight:400\">Cycles DMTA en cours<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"\/>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    \n\t\t\t\t\t            \t\n\t\t\t\t\n                <\/div>\n    <\/section>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-bottom:var(--wp--preset--spacing--100); \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns has-dark-blue-700-color has-text-color has-link-color wp-elements-aef487510e74e7a31f1f759a8248433d is-layout-flex wp-container-core-columns-is-layout-cbe57604 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--100)\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div\n    class=\"Progress Progress--left Progress--scroll absolute z-[1000]\"\n    style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--blue-600); --progress-background: rgba(0, 83, 204, 0.2);\"            x-data=\"progress()\"\n        x-init=\"init({&quot;position&quot;:&quot;left&quot;,&quot;eventType&quot;:&quot;scroll&quot;,&quot;scrollOptions&quot;:{&quot;scroll_target&quot;:&quot;m\\u00e8re&quot;,&quot;container_selector&quot;:&quot;&quot;},&quot;tickerOptions&quot;:[],&quot;formOptions&quot;:[],&quot;anchorPoints&quot;:{&quot;align_points&quot;:true,&quot;points&quot;:[{&quot;element_id&quot;:&quot;notre mission&quot;,&quot;label&quot;:&quot;&quot;},{&quot;element_id&quot;:&quot;pourquoi-choisir-sygnature&quot;,&quot;label&quot;:&quot;&quot;}]},&quot;showEndDot&quot;:true,&quot;containerScrollOffset&quot;:0.2,&quot;progressThreshold&quot;:0.005})\"\n        x-cloak\n        data-position=\"left\"\n    data-event-type=\"scroll\"\n>\n    <div\n        class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div\n            class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\"  x-ref=\"fill\"        ><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-1cb39d83 wp-block-group-is-layout-flex\" style=\"padding-bottom:0\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"our-mission\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Suivi du fragment<\/h2>\n\n\n\n<p>Le suivi des fragments est guid\u00e9 par une conception bas\u00e9e sur la structure et une g\u00e9n\u00e9ration rapide de SAR pour passer efficacement des r\u00e9sultats initiaux aux pistes optimis\u00e9es.<\/p>\n\n\n\n<p>Gr\u00e2ce \u00e0 la cristallographie, la RMN ou la cryo-microscopie \u00e9lectronique, nos \u00e9quipes de conception assist\u00e9e par ordinateur (CADD) utilisent des m\u00e9thodes telles que la dynamique mol\u00e9culaire en solvants mixtes et la cartographie de l&rsquo;eau pour identifier les poches adjacentes et prioriser les opportunit\u00e9s de croissance \u00e0 haute affinit\u00e9. Nous contr\u00f4lons les propri\u00e9t\u00e9s mol\u00e9culaires \u00e0 l&rsquo;aide de m\u00e9triques d&rsquo;efficacit\u00e9 comme l&rsquo;\u00e9nergie d&rsquo;extraction (LE) et l&rsquo;\u00e9nergie de relaxation liquide (LLE). Un retour d&rsquo;information structural rapide et fiable, incluant l&rsquo;analyse PanDDA le cas \u00e9ch\u00e9ant, guide la conception it\u00e9rative assist\u00e9e par l&rsquo;IA. Les liens structuraux avec Sygnature et les biblioth\u00e8ques de criblage commerciales permettent une analyse SAR \u00ab\u00a0de proximit\u00e9\u00a0\u00bb acc\u00e9l\u00e9r\u00e9e par catalogue.   <\/p>\n\n\n\n<p>Lorsque des synth\u00e8ses sur mesure sont n\u00e9cessaires, nos fragments optimis\u00e9s permettent de s\u00e9lectionner des vecteurs \u00e0 haute valeur ajout\u00e9e pour leur \u00e9laboration. Notre expertise reconnue <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/chimie\/chimie-a-haut-debit\/\">en chimie \u00e0 haut d\u00e9bit<\/a> permet une exploration rapide de ces vecteurs, garantissant ainsi la continuit\u00e9 des cycles DMTA. <\/p>\n<\/div>\n\n\n\n<div id=\"why-choose-sygnature\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-1f3286d3 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:0\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Pourquoi choisir Sygnature Discovery pour le support FBDD\u00a0?<\/h2>\n\n\n\n<p>Nous proposons une plateforme compl\u00e8te et int\u00e9gr\u00e9e pour la d\u00e9couverte de m\u00e9dicaments par criblage de fragments, con\u00e7ue pour vous accompagner de l&rsquo;identification des cibles \u00e0 l&rsquo;optimisation des compos\u00e9s candidats avec rapidit\u00e9 et rigueur. Vous b\u00e9n\u00e9ficiez d&rsquo;une biblioth\u00e8que de fragments d\u00e9di\u00e9e et d&rsquo;une \u00e9quipe pluridisciplinaire r\u00e9unissant biologie structurale, biophysique, CAO et chimie, avec une tra\u00e7abilit\u00e9 compl\u00e8te et un retour d&rsquo;information rapide. <\/p>\n\n\n\n<p>Notre accompagnement complet couvre la production de prot\u00e9ines et la biologie structurale, incluant la cristallographie aux rayons X et la RMN, le criblage biophysique de fragments par SPR, MST et DSF, le criblage cristallographique, la chimie computationnelle avec conception assist\u00e9e par IA et la chimie m\u00e9dicinale soutenue par la g\u00e9n\u00e9ration de relations structure-activit\u00e9 \u00e0 haut d\u00e9bit. Que vous ayez besoin d&rsquo;une campagne FBDD compl\u00e8te ou d&rsquo;un soutien cibl\u00e9 \u00e0 une \u00e9tape cl\u00e9, nous adaptons notre approche \u00e0 vos objectifs. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100)\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-5 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data=\"reveal({&quot;initiallyVisible&quot;:true,&quot;element&quot;:&quot;autre&quot;,&quot;elementId&quot;:&quot;notre mission&quot;,&quot;action&quot;:&quot;vue&quot;})\" styles=\";\">\n\t        \n    \t\t<div x-show=\"show\"\n\t\t\tx-transition:enter=\"transition ease-out duration-500\"\n\t\t\tx-transition:enter-start=\"opacity-0\"\n\t\t\tx-transition:enter-end=\"opacity-100\"\n\t\t\tx-transition:leave=\"transition ease-in duration-500 absolute inset-0\"\n\t\t\tx-transition:leave-start=\"opacity-100\"\n\t\t\tx-transition:leave-end=\"opacity-0\"\n\t\t\tx-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-640x427.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"2560\" height=\"1707\" class=\"image-original \" alt=\"Laboratoire \u00e9quip\u00e9 d'instruments biophysiques de pointe pour la caract\u00e9risation des prot\u00e9ines, notamment la spectrom\u00e9trie de masse, la RMN et l'analyse de dispersion, afin d'\u00e9valuer leur identit\u00e9, leur qualit\u00e9 et leur stabilit\u00e9.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjU2MCIgaGVpZ2h0PSIxNzA3IiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-scaled.webp\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-characterization-640x427.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-6 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"561\" height=\"588\" class=\"image-original \" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTYxIiBoZWlnaHQ9IjU4OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-74f2bbf7c2f1dbcb134229150002b271\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-b8085af24bff4b40b0d89dbacd6ac6a2 wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data=\"postGrid({&quot;respondToFiltering&quot;:true,&quot;singleFilterMode&quot;:true,&quot;initialFilterSlug&quot;:&quot;&quot;})\"  class=\"Post__Grid relative\" style=\"--post-grid-grid-cols: 3; --post-grid-row-gap: 1.5rem;\" data-single-filter-mode=\"false\" data-show-all-button=\"false\" data-initial-filter=\"\">\n                            \n\n        \n        \n            <div class=\"Post__Grid-grid   flex-col relative\" 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              <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributeName=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatCount=\"indefinite\"\/>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/synnature-discovery-et-daewoong-pharma-annoncent-une-collaboration-de-recherche\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Synnature Discovery et Daewoong Pharma annoncent une collaboration de recherche<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/HTS-web-300x183.jpg 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/HTS-web-592x360.jpg 592w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/jpeg\"><img decoding=\"async\" loading=\"lazy\" width=\"592\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNjAwIiBoZWlnaHQ9IjM2NSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/HTS-web.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/HTS-web-300x183.jpg 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/HTS-web-592x360.jpg 592w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/synnature-discovery-et-daewoong-pharma-annoncent-une-collaboration-de-recherche\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Synnature Discovery et Daewoong Pharma annoncent une collaboration de recherche<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tSygnature Discovery est heureuse d&rsquo;avoir conclu un accord de collaboration de recherche avec le groupe&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tNews\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-000-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-7 is-position-sticky\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Solutions connexes  <\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-7c4158aaf8a22a35edef55f5030853b1\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d&rsquo;experts chevronn\u00e9s de l&rsquo;industrie pharmaceutique du monde entier, garantissant l&rsquo;excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-dba583183441a4533dfcd38d04a1b202\" style=\"color:#001024b3\"><\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"High Throughput Screening\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-ee47efcfe0922214ae246b4562f55da1\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">criblage \u00e0 haut d\u00e9bit<\/a><\/h3>\n\n\n\n<p>Identification int\u00e9gr\u00e9e de cibles th\u00e9rapeutiques utilisant le criblage \u00e0 haut d\u00e9bit, le criblage de fragments et une automatisation avanc\u00e9e, fournissant des points de d\u00e9part de haute qualit\u00e9 pour une d\u00e9couverte de m\u00e9dicaments r\u00e9ussie.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Hit-ID-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Hit-ID.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Hit Identification\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Hit-ID.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Hit-ID-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Hit-ID.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5e663fe54823aeda0207b0b1b6ee8797\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/identification-des-impacts\/\" type=\"page\" id=\"941\">Identification des impacts<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-a0a4485cf1595d92057798bebf30c0e2\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Fournir des r\u00e9sultats valid\u00e9s et de haute qualit\u00e9 gr\u00e2ce \u00e0 des technologies int\u00e9gr\u00e9es, une vision strat\u00e9gique et une collaboration d&rsquo;experts pour faire progresser votre programme en toute confiance.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/identification-des-impacts\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Protein-Expression-Purification-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Protein-Expression-Purification.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Protein Expression &#038; Purification\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Protein-Expression-Purification.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Protein-Expression-Purification-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Protein-Expression-Purification.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-41b17dfbb58ed9aac052c30a35ba603f\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-structural-biology\/protein-expression-and-purification\/\" type=\"page\" id=\"1546\">Expression et purification des prot\u00e9ines<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-68891547d43047e29ed82e38b04fea02\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Des prot\u00e9ines pr\u00eates \u00e0 l&#8217;emploi gr\u00e2ce \u00e0 une conception sur mesure, une purification experte et un soutien collaboratif garantissant une progression sereine de la construction au produit final.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-structural-biology\/protein-expression-and-purification\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/biophysical-assest-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/biophysical-assest.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Biophysical Assays\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/biophysical-assest.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/biophysical-assest-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/biophysical-assest.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-ccbce8fa4f815c1b253bc50d1d98ab21\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/analyses-biophysiques\/\" data-type=\"page\" data-id=\"6122\">Essais biophysiques<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-4aa93d875a805f6fb3ccde57c7c55a2d\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Solutions biophysiques \u00e0 haut d\u00e9bit pour la liaison, la cin\u00e9tique et l&rsquo;interaction avec la cible, combinant des technologies de pointe et une expertise approfondie pour guider la d\u00e9couverte de m\u00e9dicaments.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/analyses-biophysiques\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/App-Shot-Wrapper-1-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/App-Shot-Wrapper-1.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/App-Shot-Wrapper-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/App-Shot-Wrapper-1-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/App-Shot-Wrapper-1.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-3682337da7cb9cff5f89a91a0e4c58fe\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/computer-aided-drug-design\/\" type=\"page\" id=\"1086\">Conception de m\u00e9dicaments assist\u00e9e par ordinateur<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-a2605c409f88fc4401b911c63a689394\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nos capacit\u00e9s de conception de m\u00e9dicaments assist\u00e9e par ordinateur (CADD) combinent une expertise scientifique approfondie avec une infrastructure avanc\u00e9e d&rsquo;IA, d&rsquo;apprentissage automatique et d&rsquo;informatique pour soutenir une prise de d\u00e9cision plus intelligente et plus rapide tout au long du processus de d\u00e9couverte de m\u00e9dicaments.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/computer-aided-drug-design\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-640x427.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Mod\u00e8les structuraux D de biomol\u00e9cules, repr\u00e9sentant les techniques de biologie structurale pour la conception de m\u00e9dicaments, la cartographie des \u00e9pitopes et le criblage de fragments\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjU2MCIgaGVpZ2h0PSIxNzA3IiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-scaled.webp\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-640x427.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-f627666a78aed81cdd1fc17dd1f1faed\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/\" type=\"page\" id=\"1689\">Biologie structurale<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-c2783252ac1dedc188e9309366fc8e87\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Obtenez des informations structurelles qui guident une conception de m\u00e9dicaments plus intelligente gr\u00e2ce \u00e0 la cryo-microscopie \u00e9lectronique, la RMN et la cristallographie aux rayons X, appuy\u00e9es par une analyse et une collaboration d&rsquo;experts.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":9928,"parent":4340,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-7661","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>D\u00e9couverte de m\u00e9dicaments bas\u00e9e sur les fragments - Sygnature<\/title>\n<meta name=\"description\" content=\"D\u00e9couvrez des fragments d&#039;ADN de haute qualit\u00e9 gr\u00e2ce \u00e0 la plateforme FBDD de Sygnature. 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