{"id":6976,"date":"2025-12-02T09:50:20","date_gmt":"2025-12-02T09:50:20","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/"},"modified":"2026-04-23T12:25:24","modified_gmt":"2026-04-23T12:25:24","slug":"cryo-em-a-particule-unique","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/","title":{"rendered":"Cryo-EM"},"content":{"rendered":"\n<div x-data='subNav({\"anchor_map\":{\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/cristallographie-aux-rayons-x\\\/\":\"Cristallographie aux rayons X\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/cryo-em-a-particule-unique\\\/\":\"cryo-EM\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/proteines-rmn\\\/\":\"RMN macromol\\u00e9culaire\"}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" false x-cloak style=\"\">\n    <div x-ref=\"fixedNav\" class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/\" class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Biologie structurale<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' === window.location.href ? '-active' : ''\">\n                                            Cristallographie aux rayons X\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' === window.location.href ? '-active' : ''\">\n                                            cryo-EM\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' === window.location.href ? '-active' : ''\">\n                                            RMN macromol\u00e9culaire\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                    <\/ul>\n                        \n                        <div x-ref=\"scrollIndicator\" class=\"scroll-indicator\" x-show=\"showScrollIndicator\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0 transform translate-x-full\" x-transition:enter-end=\"opacity-100 transform translate-x-0\">\n                            <svg class=\"chevron-icon w-4 h-4\" viewbox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                                <path d=\"M5.65306 3.53025L10.6531 8.53025C10.7227 8.60018 10.7775 8.68297 10.8154 8.77414C10.8533 8.8653 10.8735 8.96304 10.8735 9.06175C10.8735 9.16046 10.8533 9.2582 10.8154 9.34936C10.7775 9.44053 10.7227 9.52332 10.6531 9.59325L5.65306 14.5932C5.51217 14.7341 5.32107 14.8133 5.12181 14.8133C4.92255 14.8133 4.73145 14.7341 4.59056 14.5932C4.44966 14.4523 4.37051 14.2612 4.37051 14.062C4.37051 13.8627 4.44966 13.6716 4.59056 13.5307L9.06294 9.06175L4.59056 4.59325C4.44966 4.45236 4.37051 4.26126 4.37051 4.062C4.37051 3.86274 4.44966 3.67164 4.59056 3.53075C4.73145 3.38985 4.92255 3.3107 5.12181 3.3107C5.32107 3.3107 5.51217 3.38985 5.65306 3.53075V3.53025Z\" fill=\"currentColor\"><\/path>\n                            <\/svg>\n                        <\/div>\n                    <\/div>\n                <\/div>\n            <\/div>\n\n            <!-- Mobile menu button -->\n            <button x-ref=\"navMenuButton\" type=\"button\" class=\"flex justify-center items-center py-2 whitespace-nowrap pl-5 pr-2.5 ml-auto md:hidden\" aria-label=\"Show more navigation items\" :aria-expanded=\"mobileSubMenuOpen\">\n                <span class=\"sr-only pr-2 inline-block\">More<\/span>\n\n                <svg class=\"transition duration-500 ease-in-out\" :class=\"mobileSubMenuOpen ? 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'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Cristallographie aux rayons X\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        cryo-EM\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        RMN macromol\u00e9culaire\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7fc3d43a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-fe91d411 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-542701842e2e9e9a72ea6715b50fcfb3\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">Solutions scientifiques | Science des prot\u00e9ines et biologie structurale<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-abcb392e34c1952b524bf555d9bcc659\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">Cryo-EM<\/h1>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-476fdf6f67b1f24945f89ce8dfcfdfd2\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Sygnature Discovery propose une solution compl\u00e8te, de la synth\u00e8se g\u00e9nique \u00e0 l\u2019obtention de la structure, m\u00eame pour les cibles les plus complexes. Nos capacit\u00e9s int\u00e9gr\u00e9es de cryo-microscopie \u00e9lectronique associent technologie de pointe et expertise reconnue pour vous aider \u00e0 visualiser les macromol\u00e9cules complexes avec pr\u00e9cision et rapidit\u00e9. <\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-90bb52c3aac24bb379a087a134687390\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\"><\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d6b9ab57 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-300x254.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-768x650.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas.webp 803w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-425x360.webp 425w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-640x542.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-300x254.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-768x650.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas.webp 803w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-425x360.webp 425w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-low-res-Grid-in-Atlas-640x542.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-aa44ba95d7be2dff44c637536503b178\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group children-fill-width is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">La cryo-microscopie \u00e9lectronique \u00e0 particules individuelles (cryo-ME) est une technique puissante permettant la visualisation \u00e0 haute r\u00e9solution des macromol\u00e9cules biologiques. Elle offre des avantages uniques pour l\u2019\u00e9tude de grands complexes dynamiques, de prot\u00e9ines flexibles et de prot\u00e9ines membranaires, cibles souvent moins accessibles aux m\u00e9thodes structurales alternatives telles que la cristallographie aux rayons X ou la RMN. <\/h2>\n\n\n\n<p>Chez Sygnature Discovery, nous exploitons la puissance de la cryo-microscopie \u00e9lectronique pour d\u00e9terminer les structures macromol\u00e9culaires et les \u00e9tats conformationnels difficiles \u00e0 observer autrement. Notre \u00e9quipe poss\u00e8de une solide exp\u00e9rience dans la production de prot\u00e9ines cibles difficile \u00e0 produire de haute qualit\u00e9, garantissant une pr\u00e9paration optimale des \u00e9chantillons pour les \u00e9tudes structurales.<\/p>\n\n\n\n<div style=\"margin-top:var(--wp--preset--spacing--60)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-contain has-aspect-ratio aspect-59x35 has-overlay w-full layout h-full\" style=\"\">\n            \n                            \n\n    <div class=\"w-full overflow-hidden \" style=\"min-height: \">\n                    <video title=\"5ht2a-cryo-em-solved-structure\" width=\"1290\" height=\"994\" preload=\"metadata\" playsinline muted autoplay loop decoding=\"sync\" poster=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201920%201080%22%20style%3D%22background-color%3A%20rgba%280%2C0%2C0%2C0.1%29%22%3E%3Crect%20width%3D%22100%25%22%20height%3D%22100%25%22%20fill%3D%22transparent%22%2F%3E%3C%2Fsvg%3E\" class=\"video-upload object-contain\" data='{\"responsive-videos\":\"[]\",\"responsive-images\":\"[]\"}'><source src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/5ht2a-cryo-em-solved-structure.mp4\" type=\"video\/mp4\"><\/source><\/video>\n                            <div class=\"preview-play-button absolute-center w-full h-full cursor-pointer\" title=\"Play Full Video\" true>\n                <button type=\"button\" class=\"absolute absolute-center w-16 h-16 bg-white\/80 rounded-full flex items-center justify-center\">\n                    <span class=\"sr-only\">Play Full Video<\/span>\n                    <svg width=\"17\" height=\"20\" viewbox=\"0 0 17 20\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                        <path d=\"M16.5 8.79609C17.1667 9.18099 17.1667 10.1432 16.5 10.5281L1.5 19.1884C0.833335 19.5733 9.70611e-07 19.0922 1.00426e-06 18.3224L1.76136e-06 1.00185C1.79501e-06 0.232054 0.833336 -0.24907 1.5 0.13583L16.5 8.79609Z\" fill=\"#002B46\"><\/path>\n                    <\/svg>\n                <\/button>\n            <\/div>\n            <\/div>\n\n\n    <div class=\"w-screen h-screen fixed top-0 left-0 z-[9999]\" x-show=\"videoModalOpen\" x-cloak x-transition:enter=\"transition ease-out duration-300\" x-transition:enter-start=\"opacity-0 -translate-y-4\" x-transition:enter-end=\"opacity-100 translate-y-0\">\n        <div class=\"w-full h-full absolute top-0 left-0 bg-black\/50\"><\/div>\n        <div class=\"absolute-center w-[calc(100vw-40px)] sm:w-4\/5 md:w-3\/5 lg:w-1\/2 rounded-lg bg-white\">\n            <button class=\"absolute top-3 right-3 z-10\" type=\"button\">\n                <svg data-no-theme width=\"20\" height=\"20\" viewbox=\"0 0 20 20\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                    <path d=\"M15 5L5 15\" stroke=\"#001A24\" stroke-width=\"1.25\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n                    <path d=\"M5 5L15 15\" stroke=\"#001A24\" stroke-width=\"1.25\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n               <\/svg>\n            <\/button>\n            <div class=\"w-full aspect-video relative bg-black\">\n                <video title=\"5ht2a-cryo-em-solved-structure\" width=\"1290\" height=\"994\" controls=\"1\" preload=\"metadata\" playsinline=\"1\" muted=\"0\" autoplay=\"0\" loop=\"0\" decoding=\"sync\" poster=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%22http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%22%20viewBox%3D%220%200%201920%201080%22%20style%3D%22background-color%3A%20rgba%280%2C0%2C0%2C0.1%29%22%3E%3Crect%20width%3D%22100%25%22%20height%3D%22100%25%22%20fill%3D%22transparent%22%2F%3E%3C%2Fsvg%3E\" class=\"absolute inset-0 w-full h-full object-contain video-upload modal-video\" data='{\"responsive-videos\":\"[]\"}'><source src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/5ht2a-cryo-em-solved-structure.mp4\" type=\"video\/mp4\"><\/source><\/video>\n            <\/div>\n        <\/div>\n    <\/div>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  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var(--wp--preset--color--dark-blue-600); --progress-background: rgba(0, 50, 82, 0.2);\" x-data=\"progress()\" x-init='init({\"position\":\"left\",\"eventType\":\"scroll\",\"scrollOptions\":{\"scroll_target\":\"m\\u00e8re\",\"container_selector\":\"\"},\"tickerOptions\":[],\"formOptions\":[],\"anchorPoints\":{\"align_points\":true,\"points\":[{\"element_id\":\"\\u00e9l\\u00e9ment-collant-1\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-2\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-3\",\"label\":\"\"}]},\"showEndDot\":true,\"containerScrollOffset\":0.2,\"progressThreshold\":0.005})' x-cloak data-position=\"left\" data-event-type=\"scroll\">\n    <div class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\" x-ref=\"fill\"><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d2c5c54a wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">\u00c9valuation de la qualit\u00e9 des prot\u00e9ines<\/h2>\n\n\n\n<p>La qualit\u00e9 des prot\u00e9ines est essentielle \u00e0 la r\u00e9ussite d\u2019un projet de cryo-microscopie \u00e9lectronique. Nous utilisons une s\u00e9rie d\u2019outils analytiques pour valider les \u00e9chantillons avant la pr\u00e9paration des grilles, notamment\u00a0: <\/p>\n\n\n\n<p>\u2022 Chromatographie d\u2019exclusion st\u00e9rique analytique (SEC)<\/p>\n\n\n\n<p>\u2022 Spectrom\u00e9trie de masse en tandem (MS-MS)<\/p>\n\n\n\n<p>\u2022 Analyse de la dispersion induite par flux (FIDA)<\/p>\n\n\n\n<p>\u2022 Microscopie \u00e9lectronique \u00e0 coloration n\u00e9gative<br><\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-2\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Pr\u00e9paration de grilles et collecte des donn\u00e9es<\/h2>\n\n\n\n<p>Nous pr\u00e9parons les grilles \u00e0 l\u2019aide d\u2019un Vitrobot IV interne, la norme industrielle pour la cryo-microscopie \u00e9lectronique.  <\/p>\n\n\n\n<p>Gr\u00e2ce \u00e0 des partenariats avec des infrastructures de pointe, notamment LonCEM, eBIC (Diamond Light Source) et les universit\u00e9s de Manchester, Leicester et Leeds, nous vous donnons acc\u00e8s \u00e0 des microscopes ultramodernes, comme le Titan Krios. Nos scientifiques prennent en charge le criblage et la collecte des donn\u00e9es afin de vous fournir des jeux de donn\u00e9es de haute qualit\u00e9, adapt\u00e9s \u00e0 votre projet. <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-3\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Traitement des donn\u00e9es et infrastructure<\/h2>\n\n\n\n<p>Notre syst\u00e8me de traitement de donn\u00e9es interne s\u2019appuie sur un cloud computing s\u00e9curis\u00e9 et \u00e9volutif gr\u00e2ce \u00e0 Amazon Web Services (AWS). Cette infrastructure permet une analyse rapide et \u00e0 la demande, sans d\u00e9lai ni goulot d\u2019\u00e9tranglement des ressources, garantissant ainsi le bon d\u00e9roulement de votre projet. <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-4\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Gestion de projet et att\u00e9nuation des risques<\/h2>\n\n\n\n<p>Les projets de cryo-microscopie \u00e9lectronique n\u00e9cessitent souvent une optimisation it\u00e9rative. Notre m\u00e9thodologie int\u00e8gre des points de d\u00e9cision strat\u00e9giques (arr\u00eat\/reprise) pour g\u00e9rer les risques et maximiser l\u2019efficacit\u00e9. Nous assurons une communication r\u00e9guli\u00e8re et transparente tout au long du projet, en fournissant une \u00e9valuation honn\u00eate de l\u2019avancement, les prochaines \u00e9tapes et une estimation des co\u00fbts.  <\/p>\n<\/div>\n\n\n<section class=\"Pegasus__Container w-full hidden sm:block  relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100)\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":false,\"element\":\"other\",\"elementId\":\"sticky-item-1\",\"action\":\"inview\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" 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\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Vitrobot-IV-1.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Vitrobot-IV-1-168x300.webp 168w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Vitrobot-IV-1.webp 411w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Vitrobot-IV-1-202x360.webp 202w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Vitrobot-IV-1-358x640.webp 358w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n\n\n<div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":false,\"element\":\"other\",\"elementId\":\"sticky-item-2\",\"action\":\"inview\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-225x300.webp 225w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-768x1025.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-768x1024.webp 768w, 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100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-225x300.webp 225w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-768x1025.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-768x1024.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-1151x1536.webp 1151w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-809x1080.webp 809w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-270x360.webp 270w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope-480x640.webp 480w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-Grid-into-Microscope.webp 1182w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n\n\n<div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":false,\"element\":\"other\",\"elementId\":\"sticky-item-3\",\"action\":\"inview\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-300x110.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-768x282.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-1024x376.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification.webp 1050w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-640x235.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"1050\" height=\"386\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-300x110.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-768x282.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-1024x376.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification.webp 1050w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/cryo-EM-2D-classification-640x235.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"561\" height=\"588\" class=\"image-original \" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTYxIiBoZWlnaHQ9IjU4OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   carousel-gap-1xs is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section x-data='newcarousel({\"transition\":\"slide\",\"overflow\":false,\"autoplay\":0,\"infinite\":false,\"preview\":false,\"slidesInView\":3,\"slidesInViewTablet\":2,\"slidesInViewMobile\":1.15,\"slideGap\":0,\"align\":\"left\",\"swipeScroll\":false,\"snapToSlides\":false})' x-intersect.once=\"initAutoplay()\" class=\"Content__Carousel carousel-gap-1xs wp-elements-fb65d2057bd2560903cfd81d59c7643a relative h-full\" style=\"--slides-to-show-desktop: 3; --slides-to-show-tablet: 2; --slides-to-show-mobile: 1.15; --slide-gap: 0px; --carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem;\">\n            \n    <div class=\"Carousel__WrapperOuter relative z-10\" data-carousel-anchor style=\"--carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem\">\n\n                    <div class=\"pb-10 intro-text-wrapper\">\n                <div class=\"flex flex-col md:flex-row relative\">\n                    <div class=\"Carousel__introText mb-16 md:mb-0 w-full md:w-[45%] text-left md:max-w-[708px]\">\n                        <p class=\"has-text-4-xl-font-size has-text-3-xl-font-size\">Aper\u00e7u du processus de cryo-microscopie \u00e9lectronique<\/p>\n<p>Notre approche simplifi\u00e9e, du g\u00e8ne \u00e0 la structure, \u00e9limine les retards et pr\u00e9serve l\u2019int\u00e9grit\u00e9 des \u00e9chantillons\u00a0:<\/p>\n\n                    <\/div>\n                                            <div class=\"Navigation__Arrows container md:absolute alignment vertical-top horizontal-right \" style=\"--carousel-arrow-spacing: 1%; --carousel-arrow-inset: 0rem\">\n                                                    <button x-on:click=\"previousSlide()\" class=\"Navigation__Arrows--prev flex items-center justify-center w-10 h-10 rounded-full p-2 transition-opacity duration-500\" :class=\"firstSlide ? 'opacity-50 pointer-events-none' : 'opacity-100'\" style=\"background-color:var(--wp--preset--color--blue-300);\">\n                                <span class=\"sr-only\">Previous Slide<\/span>\n                                <svg width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path d=\"M22.8047 14.6992L6.60438 14.6992\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n                                    <path d=\"M14.7031 22.8008L6.60297 14.7006L14.7031 6.60048\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n                                <\/svg>\n                            <\/button>\n                        \n                                                    <button x-on:click=\"nextSlide()\" class=\"Navigation__Arrows--next flex items-center justify-center w-10 h-10 rounded-full p-2 transition-opacity duration-500\" :class=\"lastSlide ? 'opacity-50 pointer-events-none' : 'opacity-100'\" style=\"background-color:var(--wp--preset--color--blue-300);\">\n                                <span class=\"sr-only\">Next Slide<\/span>\n                                <svg width=\"28\" height=\"28\" viewbox=\"0 0 28 28\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\n                                    <path d=\"M5.92188 14.0264H22.1222\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n                                    <path d=\"M14.0234 5.92871L22.1236 14.0289L14.0234 22.129\" stroke=\"currentColor\" stroke-width=\"1.73575\" stroke-linecap=\"round\" stroke-linejoin=\"round\"><\/path>\n                                <\/svg>\n                            <\/button>\n                        \n                        <\/div>\n                                    <\/div>\n            <\/div>\n            \n        <div x-ref=\"sliderContainer\" class=\"Carousel__Container h-full \">\n        <div class=\"Carousel__Wrapper overflow-hidden  Carousel--snap-scroll Carousel--snap-left \" style=\"\">\n            <div class=\"Carousel\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-912a7b0ba066c591583f3d12b087a236\" style=\"font-style:normal;font-weight:400\">Conception de construction<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-6c9561fa92f427ac473093b7b1c01a13\">Sur la base d\u2019une analyse de la litt\u00e9rature, de mod\u00e9lisation et de nos exp\u00e9riences ant\u00e9rieures, y compris les prot\u00e9ines accessoires si n\u00e9cessaire.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-6cf51d9d8e73f87a8963ef493354d947\" style=\"font-style:normal;font-weight:400\">\u00c9tudes de faisabilit\u00e9 \u00e0 petite \u00e9chelle<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-ecf3ddd4173906b0f1ce17ee3c919eb2\">Des exp\u00e9riences d\u2019expression et de purification visant \u00e0 identifier la combinaison h\u00f4te\/construction optimale, appuy\u00e9es par une analyse de contr\u00f4le qualit\u00e9 rigoureuse.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-26378d2b48a6a03fc4d69156d16b29ee\" style=\"font-style:normal;font-weight:400\">Mise \u00e0 l\u2019\u00e9chelle<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-18ff2d444cbbebb01543b871ceaace29\">Production de la ou des prot\u00e9ines cibles, en qualit\u00e9 et en quantit\u00e9 suffisantes pour la pr\u00e9paration de la grille, avec des tests de contr\u00f4le qualit\u00e9 tels que SEC, SDS-PAGE, FIDA, spectrom\u00e9trie de masse et ME \u00e0 coloration n\u00e9gative.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-7f0abb724124ce5c383036cd0931488b\" style=\"font-style:normal;font-weight:400\">Pr\u00e9paration et criblage de grilles<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-5d5fea71ade478448bc0527d50a59172\">Pr\u00e9paration et s\u00e9lection internes de la grille avec des ensembles de donn\u00e9es de test pour la classification 2D et 3D.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-8fa759b86d54dd5ad0ca3ceca7fa7c97\" style=\"font-style:normal;font-weight:400\">Collecte compl\u00e8te des donn\u00e9es<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-ac0c940a8029071ce1781566845e98a4\">Acc\u00e8s aux microscopes Titan Krios par nos scientifiques.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-61721bd9 wp-block-group-is-layout-flex\" style=\"border-radius:24px;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-c151cebb wp-block-group-is-layout-flex\" style=\"margin-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h4 class=\"wp-block-heading has-dark-blue-700-color has-text-color has-link-color has-text-3-xl-font-size wp-elements-1343aa0c69d4453a07587cf2465b1975\" style=\"font-style:normal;font-weight:400\">Traitement et mod\u00e9lisation des donn\u00e9es<\/h4>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-fa8f8eb1 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-068fb87d0850eea43829374c38f3ad11\">Traitement rapide et s\u00e9curis\u00e9 via le logiciel cloud Amazon Web Services (AWS) \u2013 aucune file d\u2019attente requise.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    \n\t\t\t\t\t            \t\n\t\t\t\t\n                <\/div>\n    <\/section>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-color has-link-color has-text-4-xl-font-size wp-elements-d8121ef306d2eba3e2088058443bb83b wp-container-content-1d651e7a\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--50)\">\u00c9coutez l\u2019un de nos experts<\/h2>\n\n\n\n<div class=\"TestimonialCard TestimonialCard--fifty_fifty has-border-radius has-padding-top has-padding-bottom has-padding-right has-padding-left\" style=\"color:var(--wp--preset--color--white);background-color:var(--wp--preset--color--dark-blue-700);border-radius:var(--wp--preset--spacing--30);padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--70);padding-right:clamp(3rem, 13vw, 15rem);padding-left:clamp(3rem, 13vw, 15rem);\">\n\n            <div class=\"TestimonialCard__fifty-fifty grid grid-cols-1 lg:grid-cols-12 gap-6 items-center\">\n            <div class=\"testimonial-content flex flex-col justify-between h-full lg:col-span-7 \">\n                                    <blockquote class=\"TestimonialCard__quote relative mb-8\">\n                        <div class=\"relative z-10 has-text-3-xl-font-size leading-tight\"><p><em>\u00ab\u00a0We can support all stages of a single particle cryo-EM project from construct design through to refined structure. Protein quality is the key factor for structure determination by cryo-EM and often the most interesting targets are the toughest to produce. We have extensive experience in producing difficult proteins, including membrane proteins.\u00a0\u00bb<\/em><\/p>\n<\/div>\n                    <\/blockquote>\n                                \n                <div class=\"testimonial-avatar\">\n                    <figure class=\"Avatar flex items-center text-left group md:min-w-64 -small \" style=\"\" itemscope itemtype=\"https:\/\/schema.org\/Person\">\n        <div class=\"Avatar__Image w-16 h-16 rounded-full overflow-hidden mr-6 flex-shrink-0\">\n        <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1-150x150.webp 150w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"150\" height=\"150\" class=\"w-full object-cover\" alt=\"Profile picture of Valerie Pye\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" itemprop=\"image\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMzAwIiBoZWlnaHQ9IjMwMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1-150x150.webp 150w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n    <\/div>\n        <figcaption class=\"Avatar__Content\">\n        <h4 class=\"mb-1 font-medium\" itemprop=\"name\">Valerie Pye<\/h4>\n                    <p class=\"opacity-80 !mb-0\" itemprop=\"jobTitle\">Associate Director of Protein Science and Structural Biology<\/p>\n            <\/figcaption>\n<\/figure>\n\n                <\/div>\n            <\/div>\n            \n                            <div class=\"TestimonialCard__image lg:col-span-5 aspect-square rounded-lg overflow-hidden p-4 \">\n                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1.webp 300w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"300\" height=\"300\" class=\"w-full h-full object-cover rounded-lg\" alt=\"Featured image for testimonial by Valerie Pye\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMzAwIiBoZWlnaHQ9IjMwMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Valerie-Pye-PhD-e1682545494221-300x300-1.webp 300w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n                <\/div>\n                    <\/div>\n    <\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-db8ae020b0d7ab6b85a31c1d595ff20f\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Centre de ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-f4f353d6f3d0ad312919a94ff2812b8b wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data='postGrid({\"respondToFiltering\":true,\"singleFilterMode\":true,\"initialFilterSlug\":\"post\"})' class=\"Post__Grid relative\" style=\"--post-grid-grid-cols: 3; 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Joournal\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/journal-paper\/multidisciplinary-review-method-for-novel-target-identification-and-prioritization-for-neurodegenerative-diseases\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Multidisciplinary review method for novel target identification and prioritization for neurodegenerative diseases<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tTatiana Rosado\u00a0Rosenstock,\u00a0Hiromitsu\u00a0Ohzeki,\u00a0Shohei\u00a0Kumagai,\u00a0Natsuno\u00a0Suda,\u00a0Colin Sambrook\u00a0Smith Abstract Target identification (Target ID) is a foundational, multi-disciplinary method for identifying\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tJournal Papers\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/introducing-our-sygnature-fsec-method\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Introducing our Sygnature-FSEC Method<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Case Study\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/introducing-our-sygnature-fsec-method\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Introducing our Sygnature-FSEC Method<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tOne SEC run, Two fluorescence readouts, highlighting the \u201cSygnature\u201d peaks with your target protein. Here\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/identification-of-novel-post-translational-modifications-of-a-recombinantly-expressed-peptide\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Identification of Novel Post Translational Modifications of a Recombinantly Expressed Peptide<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/947-O-Glycosylation-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/947-O-Glycosylation.webp 571w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"571\" height=\"322\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTcxIiBoZWlnaHQ9IjMyMiIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/947-O-Glycosylation.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/947-O-Glycosylation-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/947-O-Glycosylation.webp 571w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/identification-of-novel-post-translational-modifications-of-a-recombinantly-expressed-peptide\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Identification of Novel Post Translational Modifications of a Recombinantly Expressed Peptide<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tA client had requested to obtain a small peptide that was &lt;10kDa, normally processed by\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/ontology-driven-llm-platform-for-assayability-evidence-from-literature\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Ontology\u2011driven LLM Platform for Assayability Evidence from Literature<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/ontology-llm-assayability-evidence-poster-sygnature-discovery-300x212.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/ontology-llm-assayability-evidence-poster-sygnature-discovery-509x360.webp 509w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"509\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"Diagram showing an LLM\u2011enabled, ontology\u2011driven workflow for extracting and ranking assayability evidence from biomedical literature\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAyNCIgaGVpZ2h0PSI3MjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/ontology-llm-assayability-evidence-poster-sygnature-discovery.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/ontology-llm-assayability-evidence-poster-sygnature-discovery-300x212.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/ontology-llm-assayability-evidence-poster-sygnature-discovery-509x360.webp 509w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/ontology-driven-llm-platform-for-assayability-evidence-from-literature\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Ontology\u2011driven LLM Platform for Assayability Evidence from Literature<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tAn ontology\u2011driven, LLM\u2011enabled platform for extracting and structuring assayability evidence from biomedical literature High attrition\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tPosters\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/its-been-a-hek-of-a-journey\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">It\u2019s been a HEK of a journey<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/Cell-Science-300x300.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/Cell-Science-358x360.webp 358w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"358\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNDQ2IiBoZWlnaHQ9IjQ0OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/Cell-Science.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/Cell-Science-300x300.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/04\/Cell-Science-358x360.webp 358w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/its-been-a-hek-of-a-journey\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">It\u2019s been a HEK of a journey<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tCelebrating 10 glorious years of working with HEK293-6E cells to produce high quality recombinant proteins\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/antibody-drug-conjugate-production-workflow\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Antibody Drug Conjugate Production Workflow<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x360.webp 640w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x361.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"3D molecular visualization representing diverse therapeutic modalities in drug discovery, including PROTACs, molecular glues, peptides, and RNA-targeting therapies.\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTA2NSIgaGVpZ2h0PSI2MDAiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x360.webp 640w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x361.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/antibody-drug-conjugate-production-workflow\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Antibody Drug Conjugate Production Workflow<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tIn this case study we demonstrate Sygnature Discovery\u2019s ability to provide a complete, end\u2011to\u2011end Antibody\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-18 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Solutions connexes<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e17f75369917380307a8227af22f62bc\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d\u2019experts chevronn\u00e9s de l\u2019industrie pharmaceutique du monde entier, garantissant l\u2019excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Protein &amp; Structure\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5191219c2e3f32f7b49742142e92c0b0\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/\">Prot\u00e9ines et structure<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-6d0ad0b56328052437b8544c1326311a\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Page d\u2019accueil du d\u00e9partement de prot\u00e9omique et de biologie structurale. Nous prenons le temps de comprendre votre objectif et les finalit\u00e9s de votre projet afin d\u2019adapter notre approche en cons\u00e9quence. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Membrane-Proteins-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Membrane-Proteins.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Membrane Proteins\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Membrane-Proteins.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Membrane-Proteins-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Membrane-Proteins.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5959de2af49e56dcb607825f6d97c91d\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-and-structural-biology\/membrane-proteins\/\">Prot\u00e9ines membranaires<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e5222b07b71a2f136815d4cf3b5d3a43\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Cette classe de prot\u00e9ines complexe et diversifi\u00e9e compte parmi les plus pr\u00e9cieuses pour la d\u00e9couverte de m\u00e9dicaments. Chez Sygnature, nous disposons d\u2019une \u00e9quipe de sp\u00e9cialistes d\u00e9di\u00e9e \u00e0 la production de ces cibles difficiles \u00e0 ma\u00eetriser.   <\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-and-structural-biology\/membrane-proteins\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-NMR-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-NMR.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Protein NMR\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-NMR.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-NMR-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-NMR.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-1595e0e0eebc2cf7f39b2d88cda53508\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-and-structural-biology\/protein-nmr\/\">RMN des prot\u00e9ines<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-7a7f64cbe6b5f767502c22ffd34d03a6\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous proposons divers services de RMN, notamment la caract\u00e9risation des prot\u00e9ines et la liaison des ligands en solution, la d\u00e9couverte de m\u00e9dicaments bas\u00e9e sur des fragments et la d\u00e9termination de la structure des g\u00e8nes par RMN.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-and-structural-biology\/protein-nmr\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/X-ray-crystallography-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/X-ray-crystallography.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"X-ray crystallography\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/X-ray-crystallography.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/X-ray-crystallography-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/X-ray-crystallography.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-c9ebf0f6a2432bc13f0c1dca12d1349f\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-structural-biology\/x-ray-crystallography\/\">cristallographie aux rayons X<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-47aea289ec156bc384be0859d789ba17\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous proposons non seulement un service complet allant du g\u00e8ne \u00e0 la structure par cristallographie aux rayons X, mais nous accompagnons \u00e9galement votre projet gr\u00e2ce \u00e0 notre expertise et \u00e0 nos connaissances, selon une approche par \u00e9tapes cl\u00e9s.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-structural-biology\/x-ray-crystallography\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":8016,"parent":4386,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-6976","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cryo-EM<\/title>\n<meta name=\"description\" content=\"Cryo-microscopie \u00e9lectronique \u00e0 particules individuelles chez Sygnature Discovery pour le d\u00e9veloppement d&#039;anticorps th\u00e9rapeutiques contre les RCPG, bas\u00e9 sur la structure.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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