{"id":5222,"date":"2025-11-20T12:59:31","date_gmt":"2025-11-20T12:59:31","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/"},"modified":"2026-02-06T21:40:33","modified_gmt":"2026-02-06T21:40:33","slug":"biologie-structurale","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/","title":{"rendered":"Biologie structurale"},"content":{"rendered":"\n<div x-data='subNav({\"anchor_map\":{\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/expression-et-purification-des-proteines\\\/\":\"Expression et purification des prot\\u00e9ines\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/proteines-membranaires\\\/\":\"Prot\\u00e9ines membranaires\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/anticorps-et-biotherapie\\\/\":\"Anticorps et produits bioth\\u00e9rapeutiques\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/biologie-structurale\\\/\":\"Biologie structurale\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/cristallographie-aux-rayons-x\\\/\":\"Cristallographie aux rayons X\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/cryo-em-a-particule-unique\\\/\":\"cryo-EM\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/proteines-rmn\\\/\":\"RMN\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/caracterisation-des-proteines\\\/\":\"Caract\\u00e9risation des prot\\u00e9ines\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/caracterisation-des-proteines\\\/spectrometrie-de-masse-des-proteines\\\/\":\"Spectrom\\u00e9trie de masse\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/science-des-proteines-et-biologie-structurale\\\/caracterisation-des-proteines\\\/fida\\\/\":\"FIDA\"}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" false x-cloak style=\"\">\n    <div x-ref=\"fixedNav\" class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/\" class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Prot\u00e9ines et structure<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/expression-et-purification-des-proteines\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/expression-et-purification-des-proteines\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/expression-et-purification-des-proteines\/' === window.location.href ? '-active' : ''\">\n                                            Expression et purification des prot\u00e9ines\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-membranaires\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-membranaires\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-membranaires\/' === window.location.href ? '-active' : ''\">\n                                            Prot\u00e9ines membranaires\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/anticorps-et-biotherapie\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/anticorps-et-biotherapie\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/anticorps-et-biotherapie\/' === window.location.href ? '-active' : ''\">\n                                            Anticorps et produits bioth\u00e9rapeutiques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/biologie-structurale\/' === window.location.href ? '-active' : ''\">\n                                            Biologie structurale\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' === window.location.href ? '-active' : ''\">\n                                            Cristallographie aux rayons X\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' === window.location.href ? '-active' : ''\">\n                                            cryo-EM\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' === window.location.href ? '-active' : ''\">\n                                            RMN\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/' === window.location.href ? '-active' : ''\">\n                                            Caract\u00e9risation des prot\u00e9ines\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/' === window.location.href ? '-active' : ''\">\n                                            Spectrom\u00e9trie de masse\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/' === window.location.href ? 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'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Biologie structurale\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cristallographie-aux-rayons-x\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Cristallographie aux rayons X\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        cryo-EM\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/proteines-rmn\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        RMN\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Caract\u00e9risation des prot\u00e9ines\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/spectrometrie-de-masse-des-proteines\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Spectrom\u00e9trie de masse\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/\" class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/caracterisation-des-proteines\/fida\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        FIDA\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7fc3d43a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-fe91d411 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-84663cda7e213b8319cc1bca9e72d573\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">Solutions scientifiques | Science des prot\u00e9ines et biologie structurale<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-194864ea5b27026679a8376e0fefc60c\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">Biologie structurale<\/h1>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-7fa87c3e9a0ae9000f6138f224d66ad8\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Chez Sygnature Discovery, nous vous aidons \u00e0 acqu\u00e9rir les connaissances structurales essentielles \u00e0 une conception de m\u00e9dicaments plus efficace. Nos scientifiques conjuguent des techniques de pointe \u00e0 une expertise approfondie pour r\u00e9v\u00e9ler le comportement des prot\u00e9ines et des acides nucl\u00e9iques au niveau mol\u00e9culaire, transformant ainsi des donn\u00e9es complexes en strat\u00e9gies concr\u00e8tes pour votre programme. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d6b9ab57 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-300x173.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-768x442.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-1024x589.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology.webp 1379w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-626x360.webp 626w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-640x368.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Structure mol\u00e9culaire 3D et diagramme en ruban illustrant les techniques de science des prot\u00e9ines et de biologie structurale telles que la cryo-microscopie \u00e9lectronique, la cristallographie aux rayons X et la spectroscopie RMN.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-300x173.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-768x442.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-1024x589.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology.webp 1379w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-626x360.webp 626w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/protein-science-structural-biology-640x368.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-8f86441d1d55a740c2fcc2498107c4a9\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Nous s\u00e9lectionnons l\u2019approche structurale la plus adapt\u00e9e \u00e0 votre cible sp\u00e9cifique, qu\u2019il s\u2019agisse d\u2019une prot\u00e9ine ou d\u2019un acide nucl\u00e9ique, et nous l\u2019alignons sur les objectifs de votre projet.  <\/h2>\n\n\n\n<p>Cela pourrait inclure la confirmation de la liaison des compos\u00e9s, l\u2019assistance \u00e0 la conception de m\u00e9dicaments bas\u00e9e sur la structure, la cartographie des \u00e9pitopes, la r\u00e9alisation de criblages de fragments ou le soutien d\u2019autres applications.<\/p>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">Nos solutions vont bien au-del\u00e0 de la production de coordonn\u00e9es atomiques. Nous proposons une analyse structurelle 3D compl\u00e8te, partageons les enseignements tir\u00e9s du processus et formulons des conclusions qui orientent les projets et \u00e9clairent les strat\u00e9gies de conception de m\u00e9dicaments. <\/p>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover has-aspect-ratio aspect-59x35 has-overlay absolute inset-0 w-full h-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"Mod\u00e8les structuraux D de biomol\u00e9cules, repr\u00e9sentant les techniques de biologie structurale pour la conception de m\u00e9dicaments, la cartographie des \u00e9pitopes et le criblage de fragments\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/structural-biology-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Nos solutions en Biologie Structurale<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-bac8e8fa9859eab8e531295ea4d03f8a\" style=\"color:#001024b3\">La qualit\u00e9 des prot\u00e9ines est importante. Le succ\u00e8s de toute \u00e9tudes en biologie structurale d\u00e9pend de la qualit\u00e9 de<br>la prot\u00e9ine. Nous consacrons du temps \u00e0 une planification minutieuse et appliquons notre expertise pour garantir que la prot\u00e9ine est du plus haut niveau de qualit\u00e9, augmentant significativement les probabilit\u00e9s de succ\u00e8s.  <br><\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-6517ed6772db433b734a0585b8dffc6e\" style=\"color:#001024b3\">Les projets de biologie structurale sont souvent mieux abord\u00e9 par une approche it\u00e9rative. Nous suivons une approche par \u00e9tapes avec revue des donn\u00e9es aux points cl\u00e9s et d\u00e9cision collaboratives pour les \u00e9tapes \u00e0 venir. Des d\u00e9cisions bas\u00e9s sur les r\u00e9sultats permettent de r\u00e9duire les risques et d\u2019assurer un cheminement le plus efficace.  <\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-fbbfb64c4b832f155a3c20b5525a51cb\" style=\"color:#001024b3\"><br><\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-dba583183441a4533dfcd38d04a1b202\" style=\"color:#001024b3\"><\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Dispositif de laboratoire illustrant le processus de cristallographie aux rayons X pour la d\u00e9termination des structures prot\u00e9iques \u00e0 haute r\u00e9solution.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/x-ray-crystallography-protein-structure-analysis-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-544dead813ab176017fb3a2f75ee3976\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Cristallographie aux rayons X<\/h3>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/protein-science-structural-biology\/x-ray-crystallography\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group wp-container-content-5e2576f9 is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-300x220.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-768x563.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-1024x751.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR.webp 1081w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-491x360.webp 491w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-640x469.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-300x220.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-768x563.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-1024x751.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR.webp 1081w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-491x360.webp 491w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Macromolecular-NMR-640x469.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-848576c07f590342c6c80abba81bd610\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">RMN des prot\u00e9ines<\/h3>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/expression-et-purification-des-proteines\/protein-nmr\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard  has-ivory-000-border-color is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--10);padding-bottom:var(--wp--preset--spacing--10);padding-left:var(--wp--preset--spacing--10);padding-right:var(--wp--preset--spacing--10); border-radius:24px;border-width:14px;\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-000-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-300x214.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-768x548.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-1024x731.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging.webp 1392w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-504x360.webp 504w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-640x457.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Rendu mol\u00e9culaire 3D repr\u00e9sentant la cryo-microscopie \u00e9lectronique pour la visualisation des structures prot\u00e9iques \u00e0 une r\u00e9solution quasi atomique.\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTM5MiIgaGVpZ2h0PSI5OTQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-300x214.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-768x548.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-1024x731.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging.webp 1392w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-504x360.webp 504w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo-em-protein-structure-high-resolution-imaging-640x457.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-37537c78adae0a6934313199530bfbca\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Cryo-EM<\/h3>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/cryo-em-a-particule-unique\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-353c4f5a wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-bf9f23ac wp-block-group-is-layout-constrained\" style=\"padding-bottom:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-content-justification-left is-layout-flex wp-container-core-group-is-layout-214d3d4d wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center is-style-tag has-content-secondary-color has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-3c70331813f72edddc7fdcda28c7e3b9\" style=\"font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Nos capacit\u00e9s<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-4-xl-font-size\">Quelle technique de Biologie Structurale choisir?<\/h2>\n\n\n\n<p class=\"has-text-align-left has-text-color has-link-color has-text-base-font-size wp-elements-5029c623c2a350442f2a1299ba97c74d\" style=\"color:#001024b3\">Le choix de la technique appropri\u00e9e d\u00e9pend de votre cible et des objectifs de votre projet. Nous vous conseillerons sur l\u2019option la plus adapt\u00e9e. Vous trouverez ci-dessous un r\u00e9sum\u00e9 des avantages et des inconv\u00e9nients de chaque m\u00e9thode. Pour une description d\u00e9taill\u00e9e et une comparaison des techniques que nous proposons, consultez notre <a href=\"https:\/\/www.sygnaturediscovery.com\/blog\/a-comparison-of-the-structural-techniques-used-at-sygnature-discovery-x-ray-crystallography-nmr-and-cryo-em\/\" target=\"_blank\" rel=\"noreferrer noopener\">blog ici<\/a> .   <\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2550b41c wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Accordion relative w-full mx-auto \" style=\"\">\n            \n        <div>\n        <div class=\"acf-innerblocks-container\">\n<div x-data=\"accordionPanel(1, '', false)\" class=\"Accordion__Panel mb-2 wp-elements-43c5d501ac0bcdfe1e0e213fa93e66e1\" :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Cristallographie aux rayons X<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Tables pegasus-block relative\" x-data=\"{ tooltipOpen: false }\">\n  <div class=\"Tables_scroll overflow-x-auto w-full max-w-[80vw] sm:max-w-none\">\n                                                                                                                                                                                                                            \n    <table class=\"Tables-table min-w-max table-auto overflow-hidden  Tables-padding-small\" style=\"--vertical-border-color: rgba(157, 175, 190, 0,2); --horizontal-border-color: rgba(157, 175, 190, 0,2); border-radius: 1.5rem; border: 1px solid rgba(0,0,0,0.1);\">\n      \n            <thead>\n        <tr>\n                                                    <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Avantages\n                  <\/div>\n                <\/th>\n                              <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Inconv\u00e9nients\n                  <\/div>\n                <\/th>\n                                            <\/tr>\n      <\/thead>\n      \n      <tbody>\n                                                      <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>techniques bien \u00e9tablies<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>N\u00e9cessite la cristallisation de l\u2019\u00e9chantillon<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Permet d\u2019atteindre une r\u00e9solution atomique de la structure macromol\u00e9culaire \u00e0 l\u2019\u00e9tat cristallin<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les cristaux doivent \u00eatre bien ordonn\u00e9s pour obtenir une diffraction \u00e0 haute r\u00e9solution.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>D\u00e9bit \u00e9lev\u00e9 une fois le syst\u00e8me cristallin \u00e9tabli<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Conformation unique<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Aucune limitation de taille pour les macromol\u00e9cules<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Dommages caus\u00e9s par les radiations \u2013 ceux-ci peuvent \u00eatre att\u00e9nu\u00e9s dans une certaine mesure.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>La collecte, le traitement et l\u2019analyse des donn\u00e9es sont relativement rapides.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les contacts cristallins peuvent influencer la conformation.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                                                                \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>N\u00e9cessit\u00e9 de r\u00e9soudre la phase des donn\u00e9es de diffraction pour calculer la densit\u00e9 \u00e9lectronique<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                                                                \n                \n                                                                  \n                \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                \n                \n                <td class=\"Tables-cell\" style=\"min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Une source de rayons X (interne ou synchrotron) est n\u00e9cessaire, ainsi qu\u2019un goniom\u00e8tre, un d\u00e9tecteur, etc. adapt\u00e9s \u00e0 la collecte des donn\u00e9es.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                        <\/tbody>\n\n    <\/table>\n  <\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\" class=\"Accordion__Panel mb-2 wp-elements-023f5ddb93c88c72d928b74acbb555c3\" :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">RMN des prot\u00e9ines<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Tables pegasus-block relative\" x-data=\"{ tooltipOpen: false }\">\n  <div class=\"Tables_scroll overflow-x-auto w-full max-w-[80vw] sm:max-w-none\">\n                                                                                                                                                                                                                                                  \n    <table class=\"Tables-table min-w-max table-auto overflow-hidden  Tables-padding-small\" style=\"--vertical-border-color: rgba(157, 175, 190, 0,2); --horizontal-border-color: rgba(157, 175, 190, 0,2); border-radius: 1.5rem; border: 1px solid rgba(0,0,0,0.1);\">\n      \n            <thead>\n        <tr>\n                                                    <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Avantages\n                  <\/div>\n                <\/th>\n                              <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Inconv\u00e9nients\n                  <\/div>\n                <\/th>\n                                            <\/tr>\n      <\/thead>\n      \n      <tbody>\n                                                      <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Technique non destructive<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les prot\u00e9ines dont la masse mol\u00e9culaire se situe entre 5 et 25 kDa n\u00e9cessitent un marquage uniforme avec les isotopes 15N et 13C. Une deut\u00e9ration partielle est parfois n\u00e9cessaire. <\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>La structure macromol\u00e9culaire peut \u00eatre d\u00e9termin\u00e9e en solution, sous une large gamme de conditions de force ionique, de pH (&lt; 7,4) et de temp\u00e9rature.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les isotopes n\u00e9cessaires au marquage des prot\u00e9ines sont co\u00fbteux et le co\u00fbt augmente comme suit par L de milieu : 15N(\u00a3)&lt; 13C(\u00a3x8)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les peptides dont la masse mol\u00e9culaire maximale est de 3 \u00e0 4 kDa ne n\u00e9cessitent pas d\u2019enrichissement isotopique.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Une concentration \u00e9lev\u00e9e de l\u2019\u00e9chantillon est requise (~1 mM). Impossible d\u2019attribuer les atomes N et C. <\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>La RMN en solution permet d\u2019explorer un large \u00e9ventail de propri\u00e9t\u00e9s macromol\u00e9culaires et ne se limite pas \u00e0 la d\u00e9termination de la structure :<\/p>\n<ul>\n<li>Dynamique<\/li>\n<li>Repliment<\/li>\n<li>Interactions<\/li>\n<li>R\u00e9actions cin\u00e9tiques en temps r\u00e9el<\/li>\n<\/ul>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>La synth\u00e8se prot\u00e9ique de novo est la seule m\u00e9thode disponible pour incorporer des isotopes dans les prot\u00e9ines, et elle est principalement limit\u00e9e aux syst\u00e8mes d\u2019expression d\u2019E. coli ou libre de cellule.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                                                                \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Une concentration \u00e9lev\u00e9e en prot\u00e9ines est requise, et celles-ci doivent rester stables en solution pendant une p\u00e9riode allant de quelques minutes \u00e0 plusieurs heures.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                                                                \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Les \u00e9chantillons oligom\u00e9riques et\/ou h\u00e9t\u00e9rog\u00e8nes sont difficiles \u00e0 traiter<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                                                                \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>L\u2019acquisition, le traitement et l\u2019analyse des donn\u00e9es sont relativement lents.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                                                                \n                \n                                                                  \n                \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                \n                \n                <td class=\"Tables-cell\" style=\"min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Un spectrom\u00e8tre RMN (au-dessus de 500 MHz), \u00e9quip\u00e9 d\u2019une cryosonde, est n\u00e9cessaire pour l\u2019acquisition des donn\u00e9es.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                        <\/tbody>\n\n    <\/table>\n  <\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\" class=\"Accordion__Panel mb-2 wp-elements-a9c6d161923764c692bda044d6742b0f\" :class=\"panelOpen ? 'Accordion__Panel--open' : ''\" style=\"border-top-width:0px;border-top-style:none;border-bottom-width:0px;border-bottom-style:none;   \">\n        <div class=\"Accordion__Title\">\n        <button type=\"button\" x-on:click=\"togglePanel()\" class=\"w-full flex justify-start group relative items-center\" style=\"color:#101828;\">\n           \n            <span class=\"mr-6\">\n                <svg x-show=\"panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewbox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16ZM29 16C29 18.5712 28.2376 21.0846 26.8091 23.2224C25.3807 25.3603 23.3503 27.0265 20.9749 28.0104C18.5995 28.9944 15.9856 29.2518 13.4638 28.7502C10.9421 28.2486 8.6257 27.0105 6.80762 25.1924C4.98953 23.3743 3.75141 21.0579 3.2498 18.5362C2.74819 16.0144 3.00563 13.4006 3.98957 11.0251C4.97351 8.64968 6.63975 6.61935 8.77759 5.1909C10.9154 3.76244 13.4288 3 16 3C19.4467 3.00364 22.7512 4.37445 25.1884 6.81163C27.6256 9.24882 28.9964 12.5533 29 16ZM27 16C27 13.8244 26.3549 11.6977 25.1462 9.88873C23.9375 8.07979 22.2195 6.66989 20.2095 5.83733C18.1995 5.00476 15.9878 4.78692 13.854 5.21136C11.7202 5.6358 9.76021 6.68345 8.22183 8.22183C6.68345 9.7602 5.63581 11.7202 5.21137 13.854C4.78693 15.9878 5.00477 18.1995 5.83733 20.2095C6.66989 22.2195 8.07979 23.9375 9.88873 25.1462C11.6977 26.3549 13.8244 27 16 27C18.9164 26.9967 21.7123 25.8367 23.7745 23.7745C25.8367 21.7123 26.9967 18.9164 27 16Z\" fill=\"#005DE5\"><\/path>\n                <\/svg>\n                <svg x-show=\"!panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewbox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M16 3C13.4288 3 10.9154 3.76244 8.77759 5.1909C6.63975 6.61935 4.97351 8.64968 3.98957 11.0251C3.00563 13.4006 2.74819 16.0144 3.2498 18.5362C3.75141 21.0579 4.98953 23.3743 6.80762 25.1924C8.6257 27.0105 10.9421 28.2486 13.4638 28.7502C15.9856 29.2518 18.5995 28.9944 20.9749 28.0104C23.3503 27.0265 25.3807 25.3603 26.8091 23.2224C28.2376 21.0846 29 18.5712 29 16C28.9964 12.5533 27.6256 9.24882 25.1884 6.81163C22.7512 4.37445 19.4467 3.00364 16 3ZM16 27C13.8244 27 11.6977 26.3549 9.88873 25.1462C8.07979 23.9375 6.66989 22.2195 5.83733 20.2095C5.00477 18.1995 4.78693 15.9878 5.21137 13.854C5.63581 11.7202 6.68345 9.7602 8.22183 8.22183C9.76021 6.68345 11.7202 5.6358 13.854 5.21136C15.9878 4.78692 18.1995 5.00476 20.2095 5.83733C22.2195 6.66989 23.9375 8.07979 25.1462 9.88873C26.3549 11.6977 27 13.8244 27 16C26.9967 18.9164 25.8367 21.7123 23.7745 23.7745C21.7123 25.8367 18.9164 26.9967 16 27ZM22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H17V21C17 21.2652 16.8946 21.5196 16.7071 21.7071C16.5196 21.8946 16.2652 22 16 22C15.7348 22 15.4804 21.8946 15.2929 21.7071C15.1054 21.5196 15 21.2652 15 21V17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H15V11C15 10.7348 15.1054 10.4804 15.2929 10.2929C15.4804 10.1054 15.7348 10 16 10C16.2652 10 16.5196 10.1054 16.7071 10.2929C16.8946 10.4804 17 10.7348 17 11V15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16Z\" fill=\"#001024\" fill-opacity=\"0.5\"><\/path>\n                <\/svg>\n            <\/span>\n           \n            <span class=\"panel-title text-left\" :class=\"panelOpen ? 'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Cryo-ME<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Tables pegasus-block relative\" x-data=\"{ tooltipOpen: false }\">\n  <div class=\"Tables_scroll overflow-x-auto w-full max-w-[80vw] sm:max-w-none\">\n                                                                                                                                                                                \n    <table class=\"Tables-table min-w-max table-auto overflow-hidden  Tables-padding-small\" style=\"--vertical-border-color: rgba(157, 175, 190, 0,2); --horizontal-border-color: rgba(157, 175, 190, 0,2); border-radius: 1.5rem; border: 1px solid rgba(0,0,0,0.1);\">\n      \n            <thead>\n        <tr>\n                                                    <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Avantages\n                  <\/div>\n                <\/th>\n                              <th class=\"Tables-header \" style=\"\">\n                  <div class=\"has-text-xl-font-size font-medium text-white  text-center\">\n                    Inconv\u00e9nients\n                  <\/div>\n                <\/th>\n                                            <\/tr>\n      <\/thead>\n      \n      <tbody>\n                                                      <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Adapt\u00e9 aux grands complexes macromol\u00e9culaires<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>L\u2019observation des petites prot\u00e9ines (&lt;150 kDa) est difficile\u00a0; leur taille peut \u00eatre augment\u00e9e par l\u2019ajout de partenaires de liaison.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Permet d\u2019atteindre une r\u00e9solution quasi atomique des prot\u00e9ines dans leur \u00e9tat natif (congel\u00e9 hydrat\u00e9).<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>L\u2019acquisition, le traitement et l\u2019analyse des donn\u00e9es sont relativement lents.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Plusieurs \u00e9tats d\u2019une macromol\u00e9cule peuvent \u00eatre purifi\u00e9s in silico \u00e0 partir d\u2019un seul ensemble de donn\u00e9es.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Co\u00fbteux en calcul (stockage de donn\u00e9es et GPU)<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-even\" style=\"background-color: #FCF8F3;\">\n              \n                                                                                              \n                \n                                                                  \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Macromol\u00e9cules observ\u00e9es dans l\u2019espace r\u00e9el, sans probl\u00e8me de phase<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                                                  \n                \n                <td class=\"Tables-cell\" style=\"border-bottom: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Dommages caus\u00e9s par les radiations \u2013 ceux-ci peuvent \u00eatre att\u00e9nu\u00e9s dans une certaine mesure.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                                              <tr class=\"Tables-row Tables-row-odd\" style=\"background-color: #F5EFE6;\">\n              \n                                                                                                                                \n                \n                                                                  \n                \n                \n                <td class=\"Tables-cell\" style=\"border-right: 1px solid rgba(157, 175, 190, 0,2) !important;min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      \n                    <\/div>\n                  <\/div>\n                <\/td>\n                                                                                              \n                \n                                \n                \n                \n                <td class=\"Tables-cell\" style=\"min-width: 12rem;\">\n                  <div class=\"h-full w-full flex items-center justify-center py-4\">\n                    <div class=\"has-text-base-font-size text-content-secondary font-medium text-center\">\n                      <p>Un microscope \u00e9lectronique de 200 kV ou 300 kV est n\u00e9cessaire pour la collecte des donn\u00e9es.<\/p>\n\n                    <\/div>\n                  <\/div>\n                <\/td>\n                          <\/tr>\n                        <\/tbody>\n\n    <\/table>\n  <\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n<\/div>\n    <\/div>\n    \n            <\/section><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-74f2bbf7c2f1dbcb134229150002b271\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-b8085af24bff4b40b0d89dbacd6ac6a2 wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data='postGrid({\"respondToFiltering\":true,\"singleFilterMode\":true,\"initialFilterSlug\":\"\"})' 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repeatcount=\"indefinite\"><\/animatetransform>\n                        <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributename=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatcount=\"indefinite\"><\/animate>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/the-power-of-metals-in-proteins\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">The Power of Metals in Proteins<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/03\/MIP_Image-300x106.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/03\/MIP_Image-640x225.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"225\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjU2MCIgaGVpZ2h0PSI5MDIiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/03\/MIP_Image-scaled.webp\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/03\/MIP_Image-300x106.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/03\/MIP_Image-640x225.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/the-power-of-metals-in-proteins\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">The Power of Metals in Proteins<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tIn this mini-review Sam Bloor discusses the intriguing and essential role\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/plunging-into-cryo-em\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Plunging into Cryo-EM: Precision Sample Prep for Structural Success<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo_EM_set-up-600x450-1-300x225.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo_EM_set-up-600x450-1-480x360.webp 480w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"480\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNjAwIiBoZWlnaHQ9IjQ1MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo_EM_set-up-600x450-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo_EM_set-up-600x450-1-300x225.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/cryo_EM_set-up-600x450-1-480x360.webp 480w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/plunging-into-cryo-em\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Plunging into Cryo-EM: Precision Sample Prep for Structural Success<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tCryo-EM offers unprecedented insights into complex macromolecules, but success is dependent on the quality of\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/meet-the-membrane-protein-team\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Meet the Membrane Protein Team<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Sygnature-Membrane-Protein-Science-Team-scaled-1-300x225.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Sygnature-Membrane-Protein-Science-Team-scaled-1-480x360.webp 480w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"480\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjU2MCIgaGVpZ2h0PSIxOTIwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Sygnature-Membrane-Protein-Science-Team-scaled-1.jpeg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Sygnature-Membrane-Protein-Science-Team-scaled-1-300x225.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Sygnature-Membrane-Protein-Science-Team-scaled-1-480x360.webp 480w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/meet-the-membrane-protein-team\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Meet the Membrane Protein Team<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tAt Sygnature Discovery, our Protein Science department stands out for its expertise in expressing, purifying\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/a-comparison-of-the-structural-techniques-used-at-sygnature-discovery-x-ray-crystallography-nmr-and-cryo-em\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">A Comparison of the Structural Techniques used at Sygnature Discovery: X-ray Crystallography, NMR and Cryo-EM<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Peptide_in_pocket_2-600x345-1-300x173.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Peptide_in_pocket_2-600x345-1.webp 600w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"600\" height=\"345\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"A Comparison of the Structural Techniques used at Sygnature Discovery: X-ray Crystallography, NMR and Cryo-EM\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNjAwIiBoZWlnaHQ9IjM0NSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Peptide_in_pocket_2-600x345-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Peptide_in_pocket_2-600x345-1-300x173.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Peptide_in_pocket_2-600x345-1.webp 600w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/a-comparison-of-the-structural-techniques-used-at-sygnature-discovery-x-ray-crystallography-nmr-and-cryo-em\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">A Comparison of the Structural Techniques used at Sygnature Discovery: X-ray Crystallography, NMR and Cryo-EM<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tIn this article we discuss the three techniques used for determining protein and nucleic acid\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-6 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Solutions connexes<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-7c4158aaf8a22a35edef55f5030853b1\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d\u2019experts chevronn\u00e9s de l\u2019industrie pharmaceutique du monde entier, garantissant l\u2019excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Protein &amp; Structure\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Protein-and-Structure.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5191219c2e3f32f7b49742142e92c0b0\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/\">Prot\u00e9ines et structure<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-6d0ad0b56328052437b8544c1326311a\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Page d\u2019accueil du d\u00e9partement de prot\u00e9omique et de biologie structurale. Nous prenons le temps de comprendre votre objectif et les finalit\u00e9s de votre projet afin d\u2019adapter notre approche en cons\u00e9quence. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/science-des-proteines-et-biologie-structurale\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Structure-Based Drug Design\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-935cbd7616b9aa7bec1f6068f0efc491\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/structure-based-drug-design\/\">Conception de m\u00e9dicaments bas\u00e9e sur la structure<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e3c3fd7ce9b129aa16f8cb5cff3d29bc\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous vous aidons \u00e0 concevoir de meilleurs compos\u00e9s avec une plus grande confiance. Gr\u00e2ce \u00e0 des connaissances \u00e0 l\u2019\u00e9chelle quantique et \u00e0 des simulations dynamiques, nous pr\u00e9disons l\u2019affinit\u00e9, guidons l\u2019optimisation et vous aidons \u00e0 identifier plus rapidement les candidats les plus prometteurs. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/structure-based-drug-design\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":7998,"parent":4386,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5222","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Sygnature<\/title>\n<meta name=\"description\" content=\"Obtenez des informations structurelles exploitables gr\u00e2ce \u00e0 l&#039;expertise de Sygnature Discovery en cryo-microscopie \u00e9lectronique, cristallographie aux rayons X et RMN.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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