{"id":4382,"date":"2025-11-20T09:06:34","date_gmt":"2025-11-20T09:06:34","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/toxicologie-non-regulatrice\/"},"modified":"2026-02-13T13:29:45","modified_gmt":"2026-02-13T13:29:45","slug":"toxicologie-non-regulatrice","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/toxicologie-non-regulatrice\/","title":{"rendered":"Toxicologie non r\u00e9glementaire"},"content":{"rendered":"\n<div x-data=\"subNav({&quot;anchor_map&quot;:{&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/cns-and-pain-models\\\/&quot;:&quot;Mod\\u00e8les du SNC et de la douleur&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/metabolic-models\\\/&quot;:&quot;Mod\\u00e8les de maladies m\\u00e9taboliques&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/inflammation-and-immunology-models\\\/&quot;:&quot;Mod\\u00e8les en inflammation et immunologie&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/oncology-models\\\/&quot;:&quot;Mod\\u00e8les d'oncologie&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/non-regulatory-toxicology\\\/&quot;:&quot;Toxicologie non r\\u00e9glementaire&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/metabolisme-des-medicaments-et-pharmacocinetique-dmpk\\\/etudes-pharmacocinetiques-et-pharmacodynamiques-in-vivo\\\/&quot;:&quot;Pharmacocin\\u00e9tique in vivo&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/in-vivo-pharmacology\\\/ex-vivo-tissue-analysis\\\/&quot;:&quot;Analyse tissulaire ex vivo&quot;}})\" id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" false x-cloak style=\"\">\n    <div x-ref=\"fixedNav\" class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/pharmacologie-in-vivo\/\" class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Pharmacologie in vivo<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/cns-and-pain-models\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/cns-and-pain-models\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/cns-and-pain-models\/' === window.location.href ? '-active' : ''\">\n                                            Mod\u00e8les du SNC et de la douleur\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/metabolic-models\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/metabolic-models\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/metabolic-models\/' === window.location.href ? '-active' : ''\">\n                                            Mod\u00e8les de maladies m\u00e9taboliques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/inflammation-and-immunology-models\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/inflammation-and-immunology-models\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/inflammation-and-immunology-models\/' === window.location.href ? '-active' : ''\">\n                                            Mod\u00e8les en inflammation et immunologie\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/oncology-models\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/oncology-models\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/oncology-models\/' === window.location.href ? '-active' : ''\">\n                                            Mod\u00e8les d\u2019oncologie\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/non-regulatory-toxicology\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/non-regulatory-toxicology\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/non-regulatory-toxicology\/' === window.location.href ? 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'-active' : ''\">\n                                            Pharmacocin\u00e9tique in vivo\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/ex-vivo-tissue-analysis\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/ex-vivo-tissue-analysis\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/in-vivo-pharmacology\/ex-vivo-tissue-analysis\/' === window.location.href ? 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style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Des informations pr\u00e9coces sur la s\u00e9curit\u00e9 qui vous aident \u00e0 prendre des d\u00e9cisions plus \u00e9clair\u00e9es gr\u00e2ce \u00e0 des \u00e9tudes <em>in vivo<\/em> sur mesure, une expertise translationnelle et un partenariat scientifique \u00e9troit.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d6b9ab57 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-768x513.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-1536x1025.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-539x360.webp 539w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-768x513.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-1536x1025.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-539x360.webp 539w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/in-vivo-pharmacology-microscope-data-analysis-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--100); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-084c6aec43f61d19de55fe083338bbac\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">SOUTENIR VOS RECHERCHES<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Nous proposons une \u00e9valuation pr\u00e9coce et flexible de la s\u00e9curit\u00e9 et de la tol\u00e9rance qui vous aide \u00e0 prendre des d\u00e9cisions \u00e9clair\u00e9es concernant la progression du compos\u00e9 et l\u2019allocation des ressources.  <\/h2>\n\n\n\n<p style=\"padding-bottom:var(--wp--preset--spacing--20)\">Nos services non r\u00e9glementaires de toxicologie sur les rongeurs offrent un aper\u00e7u avant le d\u00e9but des \u00e9tudes BPL formelles, avec des plans d\u2019\u00e9tude sur mesure qui s\u2019adaptent aux besoins de votre projet.<\/p>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p>Nous agissons en tant que partenaire scientifique, en vous guidant dans la conception de vos \u00e9tudes, l\u2019interpr\u00e9tation des donn\u00e9es et l\u2019int\u00e9gration des r\u00e9sultats \u00e0 votre strat\u00e9gie. En identifiant pr\u00e9cocement les probl\u00e8mes de s\u00e9curit\u00e9 potentiels, nous contribuons \u00e0 garantir que vos \u00e9tudes soient en ad\u00e9quation avec vos objectifs \u00e0 long terme. Notre \u00e9troite collaboration et la rapidit\u00e9 d\u2019ex\u00e9cution des analyses favorisent une prise de d\u00e9cision agile et \u00e9clair\u00e9e.  <\/p>\n<\/div>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover has-aspect-ratio aspect-59x35 has-overlay absolute inset-0 w-full h-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-300x145.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-768x371.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-1024x495.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-1536x743.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-640x309.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"2000\" height=\"967\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"Gros plan sur une capsule \u00e9tiquet\u00e9e \u00ab S\u00c9CURIT\u00c9 \u00bb sur une surface rouge, symbolisant l'\u00e9valuation pr\u00e9coce de la s\u00e9curit\u00e9 et de la tol\u00e9rance dans le d\u00e9veloppement des m\u00e9dicaments afin de guider une prise de d\u00e9cision \u00e9clair\u00e9e.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-300x145.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-768x371.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-1024x495.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-1536x743.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/safety-tolerability-assessment-drug-development-640x309.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100); \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-cbe57604 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80);margin-bottom:var(--wp--preset--spacing--80);padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Progress Progress--left Progress--scroll absolute z-[1000]\" style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--ivory-300); --progress-background: rgba(249, 242, 232, 0.2);\" x-data=\"progress()\" x-init='init({\"position\":\"left\",\"eventType\":\"scroll\",\"scrollOptions\":{\"scroll_target\":\"m\\u00e8re\",\"container_selector\":\"\"},\"tickerOptions\":[],\"formOptions\":[],\"anchorPoints\":{\"align_points\":true,\"points\":[{\"element_id\":\"\\u00e9l\\u00e9ment-collant-1\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-2\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-3\",\"label\":\"\"}]},\"showEndDot\":true,\"containerScrollOffset\":0.2,\"progressThreshold\":0.005})' x-cloak data-position=\"left\" data-event-type=\"scroll\">\n    <div class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\" x-ref=\"fill\"><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-57067efd wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Ce que nous proposons<\/h2>\n\n\n\n<p>Les premi\u00e8res \u00e9valuations de s\u00e9curit\u00e9 et de tol\u00e9rance sont r\u00e9alis\u00e9es sur des mod\u00e8les rongeurs na\u00effs et\/ou pertinents <em>in vivo<\/em> . Elles sont \u00e9tay\u00e9es par des \u00e9tudes de d\u00e9termination de la gamme de doses et de la dose maximale tol\u00e9r\u00e9e. Nous approfondissons la compr\u00e9hension translationnelle gr\u00e2ce \u00e0 des investigations sur les biomarqueurs et les m\u00e9canismes d\u2019action, men\u00e9es dans le cadre d\u2019\u00e9tudes sur mesure, en dehors des cadres r\u00e9glementaires formels. En combinant notre expertise <em>in vivo<\/em> \u00e0 une connaissance approfondie en pharmacologie, en pathologie et en sciences translationnelles, nous offrons une vision globale de la s\u00e9curit\u00e9 et de l\u2019efficacit\u00e9 des compos\u00e9s.   <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":false,\"element\":\"autre\",\"elementId\":\"\\u00e9l\\u00e9ment-collant-1\",\"action\":\"vue\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-768x513.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-1536x1025.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-539x360.webp 539w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"2560\" height=\"1708\" class=\"image-original \" alt=\"Laboratory setup showing a rack of syringes prepared for dose-finding and maximum tolerated dose studies, representing early safety and tolerability assessments in drug development.Laboratory setup showing a rack of syringes prepared for dose-finding and maximum tolerated dose studies, representing early safety and tolerability assessments in drug development.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-768x513.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-1536x1025.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-539x360.webp 539w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/early-safety-tolerability-assessment-dose-studies-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"561\" height=\"588\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow has-background pegasus-responsive-bg-961\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100); ;background-size:cover;background-image: url('https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/slim-gradient-bg-768x432.webp');\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-f6175775 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--60)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\">Principaux avantages<\/h2>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color wp-elements-c78dc8d513902cacccb9886afea76ed2\">Notre expertise <em>in vivo<\/em> et nos capacit\u00e9s int\u00e9gr\u00e9es vous offrent des informations pertinentes qui acc\u00e9l\u00e8rent les d\u00e9cisions et r\u00e9duisent les risques.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color wp-elements-ef0e895eb493c4c7d57882a281dce199\"><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-5e6b6c71 wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 5.35273C12.8171 5.11981 12.4197 4.99492 12.0126 4.99492C11.6054 4.99492 11.2081 5.11981 10.8741 5.35273C10.5402 5.58566 10.2857 5.91541 10.1451 6.2975L7.75508 12.75L1.30258 15.125C0.920493 15.2656 0.59074 15.5201 0.357814 15.854C0.124888 16.188 0 16.5853 0 16.9925C0 17.3997 0.124888 17.797 0.357814 18.131C0.59074 18.4649 0.920493 18.7194 1.30258 18.86L7.75508 21.25L10.1301 27.7025C10.2707 28.0846 10.5252 28.4143 10.8591 28.6473C11.1931 28.8802 11.5904 29.0051 11.9976 29.0051C12.4047 29.0051 12.8021 28.8802 13.136 28.6473C13.47 28.4143 13.7244 28.0846 13.8651 27.7025L16.2551 21.25L22.7076 18.875C23.0897 18.7344 23.4194 18.4799 23.6523 18.146C23.8853 17.812 24.0102 17.4147 24.0102 17.0075C24.0102 16.6003 23.8853 16.203 23.6523 15.869C23.4194 15.5351 23.0897 15.2806 22.7076 15.14L22.7026 15.1325ZM15.1301 19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"><\/path>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-base-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--20);font-style:normal;font-weight:500\">Environnements d\u2019\u00e9tude personnalis\u00e9s<\/h3>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-81aa8edb7062a7fefdce28849674d142\">Nous concevons des conditions d\u2019\u00e9tude permettant de r\u00e9pondre avec pr\u00e9cision \u00e0 des questions sp\u00e9cifiques de s\u00e9curit\u00e9 et de tol\u00e9rance.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-1fb62beacb04a53ff117f859c1ae6586\"><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 5.35273C12.8171 5.11981 12.4197 4.99492 12.0126 4.99492C11.6054 4.99492 11.2081 5.11981 10.8741 5.35273C10.5402 5.58566 10.2857 5.91541 10.1451 6.2975L7.75508 12.75L1.30258 15.125C0.920493 15.2656 0.59074 15.5201 0.357814 15.854C0.124888 16.188 0 16.5853 0 16.9925C0 17.3997 0.124888 17.797 0.357814 18.131C0.59074 18.4649 0.920493 18.7194 1.30258 18.86L7.75508 21.25L10.1301 27.7025C10.2707 28.0846 10.5252 28.4143 10.8591 28.6473C11.1931 28.8802 11.5904 29.0051 11.9976 29.0051C12.4047 29.0051 12.8021 28.8802 13.136 28.6473C13.47 28.4143 13.7244 28.0846 13.8651 27.7025L16.2551 21.25L22.7076 18.875C23.0897 18.7344 23.4194 18.4799 23.6523 18.146C23.8853 17.812 24.0102 17.4147 24.0102 17.0075C24.0102 16.6003 23.8853 16.203 23.6523 15.869C23.4194 15.5351 23.0897 15.2806 22.7076 15.14L22.7026 15.1325ZM15.1301 19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"><\/path>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-base-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--20);font-style:normal;font-weight:500\">\u00c9valuation compl\u00e8te du syst\u00e8me<\/h3>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-03d8aecd9d27324aa8df9c6f2e331a35\">Notre \u00e9valuation de s\u00e9curit\u00e9 couvre plusieurs organes et syst\u00e8mes physiologiques, vous offrant ainsi une vision compl\u00e8te.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-1fb62beacb04a53ff117f859c1ae6586\"><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 5.35273C12.8171 5.11981 12.4197 4.99492 12.0126 4.99492C11.6054 4.99492 11.2081 5.11981 10.8741 5.35273C10.5402 5.58566 10.2857 5.91541 10.1451 6.2975L7.75508 12.75L1.30258 15.125C0.920493 15.2656 0.59074 15.5201 0.357814 15.854C0.124888 16.188 0 16.5853 0 16.9925C0 17.3997 0.124888 17.797 0.357814 18.131C0.59074 18.4649 0.920493 18.7194 1.30258 18.86L7.75508 21.25L10.1301 27.7025C10.2707 28.0846 10.5252 28.4143 10.8591 28.6473C11.1931 28.8802 11.5904 29.0051 11.9976 29.0051C12.4047 29.0051 12.8021 28.8802 13.136 28.6473C13.47 28.4143 13.7244 28.0846 13.8651 27.7025L16.2551 21.25L22.7076 18.875C23.0897 18.7344 23.4194 18.4799 23.6523 18.146C23.8853 17.812 24.0102 17.4147 24.0102 17.0075C24.0102 16.6003 23.8853 16.203 23.6523 15.869C23.4194 15.5351 23.0897 15.2806 22.7076 15.14L22.7026 15.1325ZM15.1301 19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"><\/path>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-base-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--20);font-style:normal;font-weight:500\">Compr\u00e9hension m\u00e9canistique plus approfondie<\/h3>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-f05ee0c897dadd1944d7f6d99807680c\">Nous \u00e9tablissons un lien entre les r\u00e9sultats en mati\u00e8re de s\u00e9curit\u00e9, le mode d\u2019action et la pertinence translationnelle, vous aidant ainsi \u00e0 comprendre le \u00ab pourquoi \u00bb des donn\u00e9es.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-1fb62beacb04a53ff117f859c1ae6586\"><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 5.35273C12.8171 5.11981 12.4197 4.99492 12.0126 4.99492C11.6054 4.99492 11.2081 5.11981 10.8741 5.35273C10.5402 5.58566 10.2857 5.91541 10.1451 6.2975L7.75508 12.75L1.30258 15.125C0.920493 15.2656 0.59074 15.5201 0.357814 15.854C0.124888 16.188 0 16.5853 0 16.9925C0 17.3997 0.124888 17.797 0.357814 18.131C0.59074 18.4649 0.920493 18.7194 1.30258 18.86L7.75508 21.25L10.1301 27.7025C10.2707 28.0846 10.5252 28.4143 10.8591 28.6473C11.1931 28.8802 11.5904 29.0051 11.9976 29.0051C12.4047 29.0051 12.8021 28.8802 13.136 28.6473C13.47 28.4143 13.7244 28.0846 13.8651 27.7025L16.2551 21.25L22.7076 18.875C23.0897 18.7344 23.4194 18.4799 23.6523 18.146C23.8853 17.812 24.0102 17.4147 24.0102 17.0075C24.0102 16.6003 23.8853 16.203 23.6523 15.869C23.4194 15.5351 23.0897 15.2806 22.7076 15.14L22.7026 15.1325ZM15.1301 19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 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7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"><\/path>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-base-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--20);font-style:normal;font-weight:500\">Partenariat de collaboration<\/h3>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-f7fee7a28db2dead31b81f82007e0abe\">Nous travaillons en \u00e9troite collaboration avec votre \u00e9quipe pour garantir que la g\u00e9n\u00e9ration de donn\u00e9es soit conforme aux objectifs de votre projet.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-1fb62beacb04a53ff117f859c1ae6586\"><\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewbox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 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19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"><\/path>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-base-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--20);font-style:normal;font-weight:500\">L\u2019agilit\u00e9 scientifique au service de d\u00e9cisions \u00e9clair\u00e9es<\/h3>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-d77808221e4bade2f4ebd700a98604b8\">En alliant rigueur scientifique et flexibilit\u00e9, nous vous aidons \u00e0 identifier les risques au plus t\u00f4t, \u00e0 affiner la s\u00e9lection des compos\u00e9s et \u00e0 aller de l\u2019avant avec clart\u00e9 et confiance.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-1fb62beacb04a53ff117f859c1ae6586\"><\/p>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-6b39e634dbe4095c593657fa07ae719f\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-f4f353d6f3d0ad312919a94ff2812b8b wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data='postGrid({\"respondToFiltering\":true,\"singleFilterMode\":true,\"initialFilterSlug\":\"post\"})' 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repeatcount=\"indefinite\"><\/animatetransform>\n                        <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributename=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatcount=\"indefinite\"><\/animate>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/how-the-structure-of-g6b-b-was-determined\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">How the Structure of G6b-B was Determined<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X-300x164.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.webp 528w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"528\" height=\"288\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTI4IiBoZWlnaHQ9IjI4OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X-300x164.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.webp 528w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/how-the-structure-of-g6b-b-was-determined\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">How the Structure of G6b-B was Determined<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tOur journey started, as it often does, with an X-ray crystallography project which looked as\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/isotopic-labelling-of-proteins-in-a-eukaryotic-system\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Isotopic Labelling of Proteins in a Eukaryotic System<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Case Study\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/isotopic-labelling-of-proteins-in-a-eukaryotic-system\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Isotopic Labelling of Proteins in a Eukaryotic System<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\t\u201cAn Effective Solution for Labelling when Protein Folding is a Challenge\u201d In this case study\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/x-ray-crystallography-structure-of-erap1-complexes\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">X-ray crystallography structure of ERAP1 complexes<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"531\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAwMCIgaGVpZ2h0PSI2NzgiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/x-ray-crystallography-structure-of-erap1-complexes\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">X-ray crystallography structure of ERAP1 complexes<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tWe were asked by Greywolf Therapeutics to provide support for an endoplasmic reticulum aminopeptidase-1 (ERAP1)\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/journal-paper\/elucidating-the-relationship-between-affinity-and-potency-in-the-performance-of-therapeutic-ige\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Elucidating the relationship between affinity and potency in the performance of therapeutic IgE<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Joournal\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/journal-paper\/elucidating-the-relationship-between-affinity-and-potency-in-the-performance-of-therapeutic-ige\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Elucidating the relationship between affinity and potency in the performance of therapeutic IgE<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFrancesca Marano, Callum McKenzie, James R. Birtley, Sadaf A. Hussain, Olivia Macleod, Alexander Goodacre, Shuang\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tJournal Papers\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-craving-and-relapse\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Craving and Relapse in Addiction: Preclinical Models That Drive Discovery<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-craving-and-relapse\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Craving and Relapse in Addiction: Preclinical Models That Drive Discovery<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFocusing on the craving phase of addiction, this article examines how behavioral pharmacology models capture cue\u2011driven drug seeking and relapse vulnerability.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-substance-use-withdrawal\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Substance Use Withdrawal: How Preclinical Models Inform Treatment Development<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-substance-use-withdrawal\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Substance Use Withdrawal: How Preclinical Models Inform Treatment Development<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFocusing on the withdrawal phase of addiction, this article examines how behavioral pharmacology models assess drug dependence and therapeutic intervention in preclinical studies.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-12 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Capacit\u00e9s connexes<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e17f75369917380307a8227af22f62bc\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d\u2019experts chevronn\u00e9s de l\u2019industrie pharmaceutique du monde entier, garantissant l\u2019excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Form &amp; Formulation\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-62ada6e0951e3179aebea64551a38124\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/forme-et-formulation\/\">Forme et formulation<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-ef3202aa48e1102dd72a675eb4167c94\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Les strat\u00e9gies int\u00e9gr\u00e9es de formulation et de forme solide r\u00e9duisent les risques, am\u00e9liorent la stabilit\u00e9 et la solubilit\u00e9 et acc\u00e9l\u00e8rent le passage de la s\u00e9lection des candidats \u00e0 la clinique.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/forme-et-formulation\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/DMPK-1-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/DMPK-1.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"DMPK\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/DMPK-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/DMPK-1-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/DMPK-1.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-20a9d1f97dec8154f34e9ef075da94b8\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">DMPK<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-580ddb750647abb5e91988335168eaf9\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Des solutions DMPK int\u00e9gr\u00e9es combinant des analyses avanc\u00e9es, la mod\u00e9lisation et la bioanalyse, fournissant des informations pr\u00e9dictives qui r\u00e9duisent les risques et guident la s\u00e9lection des candidats.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/metabolisme-des-medicaments-et-pharmacocinetique-dmpk\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":7917,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-4382","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is 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