{"id":4364,"date":"2025-11-19T14:13:07","date_gmt":"2025-11-19T14:13:07","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/depistage-virtuel\/"},"modified":"2026-02-16T09:13:32","modified_gmt":"2026-02-16T09:13:32","slug":"depistage-virtuel","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/computer-aided-drug-design\/depistage-virtuel\/","title":{"rendered":"d\u00e9pistage virtuel"},"content":{"rendered":"\n<div x-data='subNav({&quot;anchor_map&quot;:{&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/bioinformatique\\\/&quot;:&quot;Bioinformatique&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/analyse-de-la-cible\\\/&quot;:&quot;Analyse des cibles&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/depistage-virtuel\\\/&quot;:&quot;d\\u00e9pistage virtuel&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/conception-de-medicaments-basee-sur-la-structure\\\/&quot;:&quot;Conception de m\\u00e9dicaments bas\\u00e9e sur la structure  &quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/ia-generative-et-apprentissage-automatique\\\/&quot;:&quot;Intelligence artificielle g\\u00e9n\\u00e9rative et apprentissage automatique&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/conception-de-medicaments-basee-sur-des-ligands\\\/&quot;:&quot;Conception de m\\u00e9dicaments bas\\u00e9e sur les ligands&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/conception-de-la-bibliotheque\\\/&quot;:&quot;Conception de biblioth\\u00e8que&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/solutions-scientifiques\\\/conception-de-medicaments-assistee-par-ordinateur\\\/predictions-admet\\\/&quot;:&quot;Pr\\u00e9diction ADMET&quot;,&quot;https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/informatique\\\/&quot;:&quot;Informatique&quot;}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" @click.away=\"mobileSubMenuOpen = false\" x-cloak style=\"\">\n    <div x-ref=\"fixedNav\"\n        class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/\" \n                                                                class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Conception de m\u00e9dicaments assist\u00e9e par ordinateur<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/bioinformatique\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/bioinformatique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/bioinformatique\/' === window.location.href ? 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'-active' : ''\"\n                                        >\n                                            d\u00e9pistage virtuel\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/conception-de-medicaments-basee-sur-la-structure\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/conception-de-medicaments-basee-sur-la-structure\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/conception-de-medicaments-basee-sur-la-structure\/' === window.location.href ? '-active' : ''\"\n                                        >\n                                            Conception de m\u00e9dicaments bas\u00e9e sur la structure  \n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/ia-generative-et-apprentissage-automatique\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/ia-generative-et-apprentissage-automatique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/ia-generative-et-apprentissage-automatique\/' === window.location.href ? '-active' : ''\"\n                                        >\n                                            Intelligence artificielle g\u00e9n\u00e9rative et apprentissage automatique\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/' === window.location.href ? '-active' : ''\"\n                                        >\n                                            Conception de m\u00e9dicaments bas\u00e9e sur les ligands\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a\n                                            href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-la-bibliotheque\/\"\n                                            class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \"\n                                            :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-la-bibliotheque\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-la-bibliotheque\/' === window.location.href ? 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'bg-blue-50 text-blue-700 font-medium' : ''\"\n                                        @click=\"mobileSubMenuOpen = false\"\n                                                                            >\n                                        Intelligence artificielle g\u00e9n\u00e9rative et apprentissage automatique\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a\n                                        href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/\"\n                                        class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \"\n                                        :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/' === window.location.href ? 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'bg-blue-50 text-blue-700 font-medium' : ''\"\n                                        @click=\"mobileSubMenuOpen = false\"\n                                                                            >\n                                        Conception de biblioth\u00e8que\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a\n                                        href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/predictions-admet\/\"\n                                        class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \"\n                                        :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/predictions-admet\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/predictions-admet\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\"\n                                        @click=\"mobileSubMenuOpen = false\"\n                                                                            >\n                                        Pr\u00e9diction ADMET\n                                    <\/a>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none\">\n                                    <a\n                                        href=\"https:\/\/www.sygnaturediscovery.com\/fr\/informatique\/\"\n                                        class=\"block px-4 py-3 rounded-lg text-sm text-gray-700 hover:bg-ivory-300 transition-colors duration-150 focus:outline-none focus:bg-ivory-300 focus:ring-2 focus:ring-inset focus:ring-blue-500 \"\n                                        :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/informatique\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/informatique\/' === window.location.href ? 'bg-blue-50 text-blue-700 font-medium' : ''\"\n                                        @click=\"mobileSubMenuOpen = false\"\n                                                                            >\n                                        Informatique\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\" >Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-7fc3d43a wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-fe91d411 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-94a1c4cd32d981f6d2509bb7c853ff28\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">solutions scientifiques | CAAD<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-091492900b6fd9f237b07a0eab590ecf\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">d\u00e9pistage virtuel<\/h1>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-4c0d466f0d39b8c6d99217202410a04f\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Nous acc\u00e9l\u00e9rons la d\u00e9couverte de compos\u00e9s actifs en criblant des milliards de compos\u00e9s en quelques heures, en combinant des outils informatiques avanc\u00e9s, des biblioth\u00e8ques soigneusement s\u00e9lectionn\u00e9es et l&rsquo;expertise de sp\u00e9cialistes pour fournir des points de d\u00e9part de haute qualit\u00e9 pour votre programme.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-48d1dab7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d6b9ab57 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width has-overlay w-full\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-300x144.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-768x369.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-1024x492.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-1536x737.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-640x307.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Visualisation de la structure mol\u00e9culaire 3D utilis\u00e9e dans la conception de m\u00e9dicaments assist\u00e9e par ordinateur, repr\u00e9sentant les approches bas\u00e9es sur la structure et sur les ligands pour la mod\u00e9lisation pr\u00e9dictive dans la d\u00e9couverte de m\u00e9dicaments.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-300x144.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-768x369.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-1024x492.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-1536x737.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/computer-aided-drug-design-molecular-model-640x307.webp 640w\"><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-8a933bb2dc7fa783e3434e7afd98fd7d\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">projection virtuelle<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Le criblage virtuel \u00e0 haut d\u00e9bit <em>in silico<\/em> (vHTS) offre une m\u00e9thode puissante, compl\u00e9mentaire et rentable pour identifier les cibles et acc\u00e9l\u00e9rer la d\u00e9couverte.  <\/h2>\n\n\n\n<p style=\"padding-bottom:var(--wp--preset--spacing--20)\">Notre \u00e9quipe de plus de 20 chimistes computationnels combine mod\u00e9lisation avanc\u00e9e, logiciels s\u00e9curis\u00e9s et \u00e0 la pointe de l&rsquo;industrie, calcul haute performance et biblioth\u00e8ques de compos\u00e9s chimiquement diversifi\u00e9es pour d\u00e9couvrir de nouveaux points de d\u00e9part chimiques pour vos programmes de d\u00e9couverte de m\u00e9dicaments.<\/p>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">Nous appliquons des techniques bas\u00e9es sur la structure et sur les ligands pour enrichir les ensembles de compos\u00e9s destin\u00e9s au criblage <em>in vitro<\/em> , am\u00e9liorant ainsi consid\u00e9rablement le succ\u00e8s de l&rsquo;identification des compos\u00e9s actifs.<\/p>\n\n\n\n<p>\u2022 <strong><a href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/structure-based-drug-design\/\">Criblage bas\u00e9 sur la structure<\/a><\/strong> utilisant des donn\u00e9es cristallographiques ou des mod\u00e8les d&rsquo;homologie pour des cibles structurellement d\u00e9finies.<\/p>\n\n\n\n<p>\u2022 <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/\"><strong>Le criblage bas\u00e9 sur les ligands<\/strong><\/a> recherche des compos\u00e9s similaires \u00e0 des mol\u00e9cules actives connues en utilisant des pharmacophores, la similarit\u00e9 forme-\u00e9lectrostatique des ligands ou les empreintes digitales des ligands.<\/p>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\"><br>En combinant le criblage virtuel \u00e0 diverses modalit\u00e9s pharmacologiques, nous permettons \u00e0 nos partenaires d&rsquo;appr\u00e9hender la biologie complexe des maladies, de surmonter les m\u00e9canismes de r\u00e9sistance et d&rsquo;explorer de nouvelles voies th\u00e9rapeutiques. Cette strat\u00e9gie flexible et ind\u00e9pendante des modalit\u00e9s pharmacologiques acc\u00e9l\u00e8re la d\u00e9couverte pr\u00e9clinique et permet de faire progresser les compos\u00e9s vers les essais cliniques avec assurance. <\/p>\n\n\n\n<p class=\"has-text-base-font-size\" style=\"padding-bottom:var(--wp--preset--spacing--20)\">Gr\u00e2ce \u00e0 notre acc\u00e8s s\u00e9curis\u00e9 \u00e0 Amazon Web Services (AWS) et \u00e0 notre infrastructure de calcul haute performance, nous pouvons ex\u00e9cuter des projets de criblage \u00e0 haut d\u00e9bit virtuel (vHTS) impliquant <strong>des milliards de compos\u00e9s en quelques heures seulement<\/strong> . Une fois les mod\u00e8les pr\u00e9par\u00e9s, nos experts analysent les donn\u00e9es, s\u00e9lectionnent les compos\u00e9s les plus prometteurs et coordonnent leur achat ou leur synth\u00e8se en vue du criblage. En quelques <strong>semaines<\/strong> , des fournisseurs internationaux de confiance livrent les compos\u00e9s dans le format adapt\u00e9 aux <strong>tests <em>in vitro,<\/em><\/strong> permettant ainsi \u00e0 votre programme de progresser sans d\u00e9lai.  <\/p>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" \n         class=\"Media object-cover has-aspect-ratio aspect-59x35 has-overlay absolute inset-0 w-full h-full\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1336\" height=\"891\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"Capture d'\u00e9cran montrant le flux de travail de criblage virtuel \u00e0 haut d\u00e9bit avec mod\u00e9lisation mol\u00e9culaire et analyse de compos\u00e9s, illustrant les approches de criblage bas\u00e9es sur la structure et sur les ligands pour l'identification des compos\u00e9s actifs.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-high-throughput-screening-vhts-computational-modeling-640x427.webp 640w\"><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Nos solutions <em>in silico<\/em><\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-1e1c9278dd21e59ff976cb32b45ee1d2\" style=\"color:#001024b3\">La qualit\u00e9 de la mati\u00e8re chimique<br> Le contr\u00f4le qualit\u00e9 est essentiel. Sygnature fournit<br> acc\u00e8s \u00e0 de vastes ressources commerciales et exclusives,<br> et collections de compos\u00e9s virtuels,<br> garantir des visites et des prospects de grande valeur.<br> Associ\u00e9 \u00e0 des ensembles de donn\u00e9es de haute qualit\u00e9,<br> m\u00e9thodologies de d\u00e9pistage robustes et<br> flux de travail valid\u00e9s, nous optimisons<br> r\u00e9sultats et r\u00e9duction des risques. <\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-dba583183441a4533dfcd38d04a1b202\" style=\"color:#001024b3\"><\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-300x167.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-768x427.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-1024x569.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-1536x854.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-640x356.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Capture d'\u00e9cran montrant le flux de travail de criblage virtuel avec analyse bas\u00e9e sur la structure et sur le ligand, y compris les nuages \u200b\u200bde points, les cartes thermiques et la visualisation de l'amarrage mol\u00e9culaire pour l'identification des compos\u00e9s actifs.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-300x167.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-768x427.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-1024x569.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-1536x854.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/virtual-screening-in-silico-high-throughput-structure-analysis-640x356.webp 640w\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5716469d690bf183e35f59cdcf5a031c\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">criblage virtuel \u00e0 tr\u00e8s haut d\u00e9bit<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-9114461e6a2ecf95ae1c7f4ea8ab8ff0\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Gr\u00e2ce \u00e0 la plateforme OpenEye Orion, nous pouvons rapidement analyser des biblioth\u00e8ques de compos\u00e9s 2D et 3D de plusieurs milliards de mol\u00e9cules, y compris les catalogues commerciaux Enamine REAL et Molport, afin de prioriser les interactions cl\u00e9s, le score hors cible, les propri\u00e9t\u00e9s et la nouveaut\u00e9 via&nbsp;:<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color wp-elements-2103609d30ba60e5611e1a349a567282\">\u2022 Criblage bas\u00e9 sur la forme avec FastROCS+ pour une comparaison rapide et hautement parall\u00e8le de milliards de conform\u00e8res. Les r\u00e9sultats peuvent \u00eatre enregistr\u00e9s par amarrage mol\u00e9culaire et\/ou raffinement des alignements de ligands \u00e0 l&rsquo;aide de mod\u00e8les th\u00e9oriques de plus haut niveau. <\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color wp-elements-2bea4c425af3d75fb8dc95e5a4f65f1a\">\u2022 \u00ab Gigadock Warp \u00bb dot\u00e9 d\u2019une intelligence artificielle pour un \u00e9chantillonnage efficace d\u2019espaces chimiques massifs.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-28146bbfb4a9da351289d78792aafc99\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">\u2022 Recherche de poches et amarrage d&rsquo;ensembles pour les approches bas\u00e9es sur des hypoth\u00e8ses.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group wp-container-content-5e2576f9 is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Image showing a grid of chemical structures representing strategically designed libraries for SAR investigations, supporting lead optimization and innovative compound synthesis.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.png\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5ca233064259fca2a9e8e3bd9b47b756\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Biblioth\u00e8ques <em>in silico<\/em> organis\u00e9es<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-79096a8df38ce17e0ba49671c7b30ecf\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous g\u00e9rons une biblioth\u00e8que organis\u00e9e d&rsquo;environ 15 millions de compos\u00e9s disponibles dans le commerce, de type t\u00eate de s\u00e9rie ou m\u00e9dicament, issus de bases de donn\u00e9es de compos\u00e9s commerciaux, ainsi que de sous-ensembles des collections Enamine REAL et Molport pour les applications bas\u00e9es sur la structure. Nous r\u00e9visons et mettons \u00e0 jour r\u00e9guli\u00e8rement notre biblioth\u00e8que virtuelle afin d&rsquo;offrir un acc\u00e8s \u00e0 une collection de criblage virtuel tr\u00e8s pertinente. <\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-300x149.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-768x380.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-1024x507.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-1536x760.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-640x317.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"3D molecular visualization showing orange and green ribbon structures with chemical scaffolds, representing STRATA\u2019s proprietary virtual library of drug-like molecules for high-throughput chemistry.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjAwMCIgaGVpZ2h0PSI5OTAiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-300x149.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-768x380.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-1024x507.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-1536x760.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/strata-exclusive-virtual-library-3d-molecular-scaffolds-640x317.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-31f20543fa29f3647a72003eafc3c06e\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">STRATA : Notre biblioth\u00e8que virtuelle exclusive<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-ab76e896f5485565f36a4a0f43eefd2e\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">STRATA propose plus de 17 millions de mol\u00e9cules propri\u00e9taires tridimensionnelles de type m\u00e9dicament, fabriqu\u00e9es \u00e0 la demande, bas\u00e9es sur des \u00e9chafaudages \u00e0 haute teneur en Fsp3 d\u00e9velopp\u00e9s dans le cadre de notre programme europ\u00e9en Lead Factory, avec une m\u00e9thodologie enti\u00e8rement valid\u00e9e pour la chimie \u00e0 haut d\u00e9bit.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-300x193.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-768x495.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati.webp 1000w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-559x360.webp 559w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-640x412.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"3D molecular visualization showing blue and purple ribbon structures with ligand docking, illustrating LeadFinder Prism screening library for in silico compound evaluation and biological testing.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAwMCIgaGVpZ2h0PSI2NDQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-300x193.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-768x495.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati.webp 1000w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-559x360.webp 559w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/leadfinder-prism-screening-library-molecular-docking-visualizati-640x412.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-95e0518cf27f9d4afadf9ceada5d8d0b\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Biblioth\u00e8que de criblage LeadFinder Prism<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-2bd7d0adf09f0394619dda6648035348\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous proposons un criblage <em>in silico<\/em> d&rsquo;un sous-ensemble de nouveaux compos\u00e9s synth\u00e9tis\u00e9s en interne \u00e0 partir de ces structures. Ces compos\u00e9s sont disponibles imm\u00e9diatement pour des tests biologiques dans le cadre de LeadFinder. <\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Image showing a grid of chemical structures representing strategically designed libraries for SAR investigations, supporting lead optimization and innovative compound synthesis.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTI1MSIgaGVpZ2h0PSI2NjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5c3578fa16a296f7b903ddbe05269766\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Biblioth\u00e8ques sur mesure<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-faf2a5e212a3dfeca96b10c0690f4c5f\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Sygnature Discovery peut concevoir des biblioth\u00e8ques de projection virtuelle sur mesure et d&rsquo;autres ensembles commerciaux adapt\u00e9s aux besoins de votre projet.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow has-background pegasus-responsive-bg-961\" style=\"  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); ;background-position:5% 100%;background-size:cover;background-image: url(&apos;https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/slim-gradient-bg-768x432.webp&apos;);\" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-a082ea85 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--60)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center is-style-tag has-text-color has-link-color has-tag-style wp-elements-589eb2fc391bfaaa67060d7cf70c2bfd\" style=\"color:#00102480;padding-top:0;padding-right:0;padding-bottom:var(--wp--preset--spacing--30);padding-left:0;--paragraph-dot-color:#005de5\">Principaux avantages<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-center has-text-4-xl-font-size\">Principaux avantages<\/h2>\n\n\n\n<p class=\"has-text-align-center has-content-secondary-color has-text-color has-link-color wp-elements-36522292e71b4f750307214a19b0e9a6\">Notre expertise en mati\u00e8re de techniques bas\u00e9es sur la structure et sur les ligands peut \u00eatre appliqu\u00e9e \u00e0<br> enrichir un ensemble de compos\u00e9s pour le criblage <em>in vitro<\/em> avec un potentiel d&rsquo;activit\u00e9 plus \u00e9lev\u00e9,<br> am\u00e9liorant consid\u00e9rablement les chances d&rsquo;identification r\u00e9ussie des cibles.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-5e6b6c71 wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media original shrink-0\"\n         style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"29\" height=\"29\" viewBox=\"0 0 29 29\" fill=\"none\" class=\"image-original \">\n<path d=\"M22.7026 15.1325L16.2551 12.75L13.8801 6.2975C13.7394 5.91541 13.485 5.58566 13.151 5.35273C12.8171 5.11981 12.4197 4.99492 12.0126 4.99492C11.6054 4.99492 11.2081 5.11981 10.8741 5.35273C10.5402 5.58566 10.2857 5.91541 10.1451 6.2975L7.75508 12.75L1.30258 15.125C0.920493 15.2656 0.59074 15.5201 0.357814 15.854C0.124888 16.188 0 16.5853 0 16.9925C0 17.3997 0.124888 17.797 0.357814 18.131C0.59074 18.4649 0.920493 18.7194 1.30258 18.86L7.75508 21.25L10.1301 27.7025C10.2707 28.0846 10.5252 28.4143 10.8591 28.6473C11.1931 28.8802 11.5904 29.0051 11.9976 29.0051C12.4047 29.0051 12.8021 28.8802 13.136 28.6473C13.47 28.4143 13.7244 28.0846 13.8651 27.7025L16.2551 21.25L22.7076 18.875C23.0897 18.7344 23.4194 18.4799 23.6523 18.146C23.8853 17.812 24.0102 17.4147 24.0102 17.0075C24.0102 16.6003 23.8853 16.203 23.6523 15.869C23.4194 15.5351 23.0897 15.2806 22.7076 15.14L22.7026 15.1325ZM15.1301 19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"\/>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-21dccfd1f74e902a10c97631c58b9220\"><strong>Capable<\/strong> de cribler des milliards de compos\u00e9s en quelques heures gr\u00e2ce \u00e0 AWS et \u00e0 la plateforme HPC Sygnature.<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color has-text-sm-font-size wp-elements-0334855d67933554f7f35ecfb20f4620\">\u2022 Acc\u00e8s \u00e9tendu \u00e0 du mat\u00e9riel de calcul haute performance s\u00e9curis\u00e9 sur la plateforme Orion pour les virtualisations \u00e0 l&rsquo;\u00e9chelle du gigabit et \u00e0 un syst\u00e8me de calcul haute performance interne Sygnature<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-f023575f0e8b3858ffcd59dbadbcda1c\">\u2022 Utilisation simultan\u00e9e r\u00e9guli\u00e8re de 20&nbsp;000 processeurs et 2&nbsp;000 GPU sur AWS<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media original shrink-0\"\n         style=\"\">\n            \n        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9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"\/>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-7866da2be96ba99ece48bb01c2adf8f8\"><strong>Diversit\u00e9<\/strong> \u2013 Acc\u00e9dez \u00e0 des biblioth\u00e8ques s\u00e9lectionn\u00e9es et exclusives, notamment STRATA<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-662825868fb73aac9d8d166f5d7ad026\">Notre acc\u00e8s bien \u00e9tabli \u00e0 Amazon Web Services (AWS) nous permet d&rsquo;ex\u00e9cuter en toute s\u00e9curit\u00e9 des projets vHTS impliquant des millions de compos\u00e9s en quelques heures, une fois le mod\u00e8le pr\u00e9par\u00e9.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-61a9a2dbff98167b79a8906c35527a83\">\u2022 Des chimioth\u00e8ques de milliards de compos\u00e9s pr\u00eates \u00e0 \u00eatre cribl\u00e9es en 2D et 3D sans aucun temps de pr\u00e9paration de base de donn\u00e9es<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-7c4d7145d8da2534ec06b94587186317\">\u2022 Plus de 14 millions de compos\u00e9s disponibles dans le commerce et plus de 30 milliards de compos\u00e9s fabriqu\u00e9s \u00e0 la demande<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" 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3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"\/>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-d4fb5adaa4b24bac1596bb1ac303b70e\" style=\"padding-top:var(--wp--preset--spacing--10)\">Des flux de travail <strong>robustes<\/strong> et int\u00e9gr\u00e9s, avec r\u00e9\u00e9valuation et triage avanc\u00e9s, permettent \u00e0 nos mod\u00e9lisateurs exp\u00e9riment\u00e9s d&rsquo;analyser les donn\u00e9es vHTS et de s\u00e9lectionner les compos\u00e9s \u00e0 acheter, \u00e0 synth\u00e9tiser ou \u00e0 cribler. Nous avons identifi\u00e9 des fournisseurs fiables \u00e0 travers le monde, capables de fournir des compos\u00e9s dans un format adapt\u00e9 au criblage <em>in vitro<\/em> en quelques semaines seulement.  <\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color has-text-sm-font-size wp-elements-c1bb754081d192aaf2022c50949cf467\">\u2022 Mise en place de flux de travail de triage semi-manuels et \u00e0 plusieurs \u00e9tapes pour le suivi.<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color has-text-sm-font-size wp-elements-37e4b10b1dd314d764147e52946d038e\">\u2022 Pipeline int\u00e9gr\u00e9 de multiples outils commerciaux et open source<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color has-text-sm-font-size wp-elements-be7e5871104e7e1058e6d57016cdbe01\">\u2022 \u00c9limination des douleurs, des signaux de toxicit\u00e9 et des \u00e9l\u00e9ments ind\u00e9sirables sp\u00e9cifiques au projet<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-2344500ed37cd8ec0e537f5aa4047694\">\u2022 Proposer un r\u00e9examen de haut niveau, par exemple une \u00e9valuation de la stabilit\u00e9 de la pose ou des calculs d&rsquo;\u00e9nergie de liaison par FMO.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-ivory-000-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-cb358442 wp-block-group-is-layout-flex\" style=\"border-radius:24px;min-height:280px;padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media original shrink-0\"\n         style=\"\">\n            \n                                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" 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19.5275C14.9943 19.5775 14.8711 19.6564 14.7688 19.7587C14.6665 19.861 14.5876 19.9843 14.5376 20.12L12.0051 26.9813L9.47758 20.125C9.42764 19.9878 9.34826 19.8633 9.24504 19.76C9.14182 19.6568 9.01725 19.5774 8.88008 19.5275L2.02383 17L8.88008 14.4725C9.01725 14.4226 9.14182 14.3432 9.24504 14.24C9.34826 14.1367 9.42764 14.0122 9.47758 13.875L12.0051 7.01875L14.5326 13.875C14.5826 14.0107 14.6615 14.134 14.7638 14.2363C14.8661 14.3386 14.9893 14.4175 15.1251 14.4675L21.9863 17L15.1301 19.5275ZM16.0051 4C16.0051 3.73478 16.1104 3.48043 16.298 3.29289C16.4855 3.10536 16.7399 3 17.0051 3H19.0051V1C19.0051 0.734784 19.1104 0.48043 19.298 0.292893C19.4855 0.105357 19.7399 0 20.0051 0C20.2703 0 20.5247 0.105357 20.7122 0.292893C20.8997 0.48043 21.0051 0.734784 21.0051 1V3H23.0051C23.2703 3 23.5247 3.10536 23.7122 3.29289C23.8997 3.48043 24.0051 3.73478 24.0051 4C24.0051 4.26522 23.8997 4.51957 23.7122 4.70711C23.5247 4.89464 23.2703 5 23.0051 5H21.0051V7C21.0051 7.26522 20.8997 7.51957 20.7122 7.70711C20.5247 7.89464 20.2703 8 20.0051 8C19.7399 8 19.4855 7.89464 19.298 7.70711C19.1104 7.51957 19.0051 7.26522 19.0051 7V5H17.0051C16.7399 5 16.4855 4.89464 16.298 4.70711C16.1104 4.51957 16.0051 4.26522 16.0051 4ZM29.0051 10C29.0051 10.2652 28.8997 10.5196 28.7122 10.7071C28.5247 10.8946 28.2703 11 28.0051 11H27.0051V12C27.0051 12.2652 26.8997 12.5196 26.7122 12.7071C26.5247 12.8946 26.2703 13 26.0051 13C25.7399 13 25.4855 12.8946 25.298 12.7071C25.1104 12.5196 25.0051 12.2652 25.0051 12V11H24.0051C23.7399 11 23.4855 10.8946 23.298 10.7071C23.1104 10.5196 23.0051 10.2652 23.0051 10C23.0051 9.73478 23.1104 9.48043 23.298 9.29289C23.4855 9.10536 23.7399 9 24.0051 9H25.0051V8C25.0051 7.73478 25.1104 7.48043 25.298 7.29289C25.4855 7.10536 25.7399 7 26.0051 7C26.2703 7 26.5247 7.10536 26.7122 7.29289C26.8997 7.48043 27.0051 7.73478 27.0051 8V9H28.0051C28.2703 9 28.5247 9.10536 28.7122 9.29289C28.8997 9.48043 29.0051 9.73478 29.0051 10Z\" fill=\"#005DE5\"\/>\n<\/svg>\n\n                \n            <\/section>\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-6243dcb3887577b29cccccac155dd22b\"><strong>\u00c9quipe exp\u00e9riment\u00e9e<\/strong> \u2013 Plus de 20 sp\u00e9cialistes poss\u00e9dant une vaste exp\u00e9rience dans la s\u00e9lection manuelle de listes de cibles.<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color has-text-sm-font-size wp-elements-412de07db06370ae1942696e01ce2ac6\">\u2022 De nombreuses \u00e9tudes de cas couvrant diverses classes de cibles, notamment les RCPG, les canaux ioniques et les kinases.<\/p>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-sm-font-size wp-elements-9615f951270fba576228e470ea6cad50\">\u2022 \u00c9valuation visuelle finale par un chimiste m\u00e9dicinal\/informatique exp\u00e9riment\u00e9 afin de garantir la synth\u00e8se possible de la mati\u00e8re chimique s\u00e9lectionn\u00e9e.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--60); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-6b39e634dbe4095c593657fa07ae719f\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-f4f353d6f3d0ad312919a94ff2812b8b wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data=\"postGrid({&quot;respondToFiltering&quot;:true,&quot;singleFilterMode&quot;:true,&quot;initialFilterSlug&quot;:&quot;post&quot;})\"  class=\"Post__Grid relative\" style=\"--post-grid-grid-cols: 3; --post-grid-row-gap: 1.5rem;\" data-single-filter-mode=\"false\" data-show-all-button=\"false\" data-initial-filter=\"post\">\n                                <div class=\"Post__Grid-filters-wrapper relative flex flex-col-reverse overflow-auto filter-between pt-4 pb-8 has-body-font-family gap-8 sm:gap-4 md:gap-0\">\n\t<div class=\"Post__Grid-filters relative inline-flex \">\n\t\t<div class=\"p-1 flex space-x-1 rounded-full items-center overflow-auto no-scrollbar bg-ivory-300\">\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" \n\t\t\t\t\t\t\t@click=\"toggleFilters('post', 'post_type', 'post_type'); isLoading = true;\" \n\t\t\t\t\t\t\tclass=\"w-auto px-6 h-9 font-normal font-body leading-none rounded-full whitespace-nowrap transition-colors ease-in-out\"\n\t\t\t\t\t\t\t:class=\"filterIsActive('post', 'post_type', 'post_type') ? 'bg-white text-black pointer-events-none' : 'bg-transparent text-black'\">\n\t\t\t\t\t\t<span>Nouvelles<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t\t\t\t\t<button type=\"button\" \n\t\t\t\t\t\t\t@click=\"toggleFilters('blog,webinar-and-podcast,technical-note,protocol,journal-paper,e-book,poster,case-study', 'post_type', 'post_type'); isLoading = true;\" \n\t\t\t\t\t\t\tclass=\"w-auto px-6 h-9 font-normal font-body leading-none rounded-full whitespace-nowrap transition-colors ease-in-out\"\n\t\t\t\t\t\t\t:class=\"filterIsActive('blog,webinar-and-podcast,technical-note,protocol,journal-paper,e-book,poster,case-study', 'post_type', 'post_type') ? 'bg-white text-black pointer-events-none' : 'bg-transparent text-black'\">\n\t\t\t\t\t\t<span>Ressources<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\n                \n\n        \n        \n            <div class=\"Post__Grid-grid   flex-col relative\" data-pegasus-filterable=\"block_67e9a552a224b30b695c153bb2430d7a\">\n                <div x-cloak x-show=\"isLoading\" class=\"absolute -top-3 -left-3 -right-3 -bottom-3 flex items-start justify-center pt-8 md:items-center md:pt-0 z-10 rounded-2xl overflow-visible transition duration-200 pointer-events-none bg-white\/80 backdrop-blur-sm\" style=\"background-color: rgb(255 255 255 \/ 80%);\">\n                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\"\n                         width=\"50\" height=\"50\" viewBox=\"0 0 40 48\"\n                         role=\"img\" aria-label=\"Loading\" style=\"color:#005DE5\">\n                        <title>Loading\u2026<\/title>\n                        <g 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                                             from=\"0 19.6318 23.7783\"\n                                              to=\"360 19.6318 23.7783\"\n                                              dur=\"1s\"\n                                              repeatCount=\"indefinite\"\/>\n                        <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributeName=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatCount=\"indefinite\"\/>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/more-papain-more-problems\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">More Papain, More Problems<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Case Study\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/more-papain-more-problems\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">More Papain, More Problems<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tThe Challenge Clients sometimes as us to generate Fab and Fc pools from a full-length&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/recombinant-%ce%b2-catenin-ctnnb1-expression-and-purification-provides-an-early-handle-for-therapeutic-targeting-of-the-wnt-signalling-pathway\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Recombinant \u03b2-catenin (CTNNB1) expression and purification provides an early handle for therapeutic targeting of the Wnt signalling pathway<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/2z6h-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/2z6h-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"531\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAwMCIgaGVpZ2h0PSI2NzgiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/2z6h.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/2z6h-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/2z6h-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/recombinant-%ce%b2-catenin-ctnnb1-expression-and-purification-provides-an-early-handle-for-therapeutic-targeting-of-the-wnt-signalling-pathway\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Recombinant \u03b2-catenin (CTNNB1) expression and purification provides an early handle for therapeutic targeting of the Wnt signalling pathway<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\t\u03b2-catenin (CTNNB1) is a multifunctional protein that plays a pivotal role in the canonical Wnt&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/optimizing-recombinant-cereblon-midi-expression-in-e-coli-through-smart-strain-choice\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Optimizing Recombinant Cereblon-Midi Expression in E. coli Through Smart Strain Choice<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Coli-300x210.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Coli.webp 377w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"377\" height=\"264\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMzc3IiBoZWlnaHQ9IjI2NCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Coli.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Coli-300x210.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Coli.webp 377w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/optimizing-recombinant-cereblon-midi-expression-in-e-coli-through-smart-strain-choice\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Optimizing Recombinant Cereblon-Midi Expression in E. coli Through Smart Strain Choice<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tIn this article we discuss our workflow for selecting the optimum E. coli strain for&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/rassembler-une-decouverte-de-medicaments-connectee-sous-un-seul-nom\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Rassembler une D\u00e9couverte de M\u00e9dicaments Connect\u00e9e Sous un Seul Nom<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Launch-announcement-blog-feature-image-FR-300x111.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Launch-announcement-blog-feature-image-FR-640x237.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"640\" height=\"237\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjAwMCIgaGVpZ2h0PSI3NDIiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Launch-announcement-blog-feature-image-FR.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Launch-announcement-blog-feature-image-FR-300x111.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Launch-announcement-blog-feature-image-FR-640x237.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/rassembler-une-decouverte-de-medicaments-connectee-sous-un-seul-nom\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Rassembler une D\u00e9couverte de M\u00e9dicaments Connect\u00e9e Sous un Seul Nom<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tDepuis plus de 20 ans, Sygnature Discovery collabore avec des entreprises biotechnologiques et pharmaceutiques pour&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tNews\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/storm-therapeutics-from-lead-to-pre-candidate-nomination-in-18-months\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">STORM Therapeutics: From Lead to Pre-Candidate Nomination in 18 Months<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/dhx9-case-study-cover-sygnature-discovery-300x176.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/dhx9-case-study-cover-sygnature-discovery-613x360.webp 613w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"613\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"Cover graphic for the DHX9 inhibitor case study showing the title From Lead to Pre Candidate Nomination in 18 Months with STORM Therapeutics and Sygnature Discovery branding.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAwMSIgaGVpZ2h0PSI1ODgiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/dhx9-case-study-cover-sygnature-discovery.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/dhx9-case-study-cover-sygnature-discovery-300x176.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/dhx9-case-study-cover-sygnature-discovery-613x360.webp 613w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/storm-therapeutics-from-lead-to-pre-candidate-nomination-in-18-months\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">STORM Therapeutics: From Lead to Pre-Candidate Nomination in 18 Months<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tAccelerating a best in class DHX9 inhibitor ahead of industry timelines.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Que s&rsquo;est-il pass\u00e9 ? Retour sur l&rsquo;ann\u00e9e 2020 !<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/generic-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/generic-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Post\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/generic-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/generic-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/generic-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Que s&rsquo;est-il pass\u00e9 ? Retour sur l&rsquo;ann\u00e9e 2020 !<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tCette ann\u00e9e restera grav\u00e9e dans les m\u00e9moires. Nous avons tous d\u00fb nous adapter, trouver de&hellip;\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tNews\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group is-vertical is-content-justification-stretch is-layout-flex wp-container-core-group-is-layout-353c4f5a wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-eb5039d6 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-c9ee0c5a wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-align-center has-text-4-xl-font-size\">FAQ<\/h2>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-a7849e3a wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Accordion relative w-full mx-auto \"\n         style=\"\">\n            \n        <div>\n        <div class=\"acf-innerblocks-container\">\n<div x-data=\"accordionPanel(1, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-1c13200fb3106577d581a455eeb715e9\"\n     :class=\"panelOpen ? 'Accordion__Panel--open' : ''\"\n     style=\"border-top-color:#f2e8d9;border-top-width:1px;border-bottom-color:#f2e8d9;border-bottom-width:1px;   \">\n        <div class=\"Accordion__Title\">\n        <button type=\"button\" x-on:click=\"togglePanel()\" \n                class=\"w-full flex justify-start group relative items-center\" \n                style=\"color:#101828;\">\n           \n            <span class=\"mr-6\">\n                <svg x-show=\"panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewBox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16ZM29 16C29 18.5712 28.2376 21.0846 26.8091 23.2224C25.3807 25.3603 23.3503 27.0265 20.9749 28.0104C18.5995 28.9944 15.9856 29.2518 13.4638 28.7502C10.9421 28.2486 8.6257 27.0105 6.80762 25.1924C4.98953 23.3743 3.75141 21.0579 3.2498 18.5362C2.74819 16.0144 3.00563 13.4006 3.98957 11.0251C4.97351 8.64968 6.63975 6.61935 8.77759 5.1909C10.9154 3.76244 13.4288 3 16 3C19.4467 3.00364 22.7512 4.37445 25.1884 6.81163C27.6256 9.24882 28.9964 12.5533 29 16ZM27 16C27 13.8244 26.3549 11.6977 25.1462 9.88873C23.9375 8.07979 22.2195 6.66989 20.2095 5.83733C18.1995 5.00476 15.9878 4.78692 13.854 5.21136C11.7202 5.6358 9.76021 6.68345 8.22183 8.22183C6.68345 9.7602 5.63581 11.7202 5.21137 13.854C4.78693 15.9878 5.00477 18.1995 5.83733 20.2095C6.66989 22.2195 8.07979 23.9375 9.88873 25.1462C11.6977 26.3549 13.8244 27 16 27C18.9164 26.9967 21.7123 25.8367 23.7745 23.7745C25.8367 21.7123 26.9967 18.9164 27 16Z\" fill=\"#005DE5\"\/>\n                <\/svg>\n                <svg x-show=\"!panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewBox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M16 3C13.4288 3 10.9154 3.76244 8.77759 5.1909C6.63975 6.61935 4.97351 8.64968 3.98957 11.0251C3.00563 13.4006 2.74819 16.0144 3.2498 18.5362C3.75141 21.0579 4.98953 23.3743 6.80762 25.1924C8.6257 27.0105 10.9421 28.2486 13.4638 28.7502C15.9856 29.2518 18.5995 28.9944 20.9749 28.0104C23.3503 27.0265 25.3807 25.3603 26.8091 23.2224C28.2376 21.0846 29 18.5712 29 16C28.9964 12.5533 27.6256 9.24882 25.1884 6.81163C22.7512 4.37445 19.4467 3.00364 16 3ZM16 27C13.8244 27 11.6977 26.3549 9.88873 25.1462C8.07979 23.9375 6.66989 22.2195 5.83733 20.2095C5.00477 18.1995 4.78693 15.9878 5.21137 13.854C5.63581 11.7202 6.68345 9.7602 8.22183 8.22183C9.76021 6.68345 11.7202 5.6358 13.854 5.21136C15.9878 4.78692 18.1995 5.00476 20.2095 5.83733C22.2195 6.66989 23.9375 8.07979 25.1462 9.88873C26.3549 11.6977 27 13.8244 27 16C26.9967 18.9164 25.8367 21.7123 23.7745 23.7745C21.7123 25.8367 18.9164 26.9967 16 27ZM22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H17V21C17 21.2652 16.8946 21.5196 16.7071 21.7071C16.5196 21.8946 16.2652 22 16 22C15.7348 22 15.4804 21.8946 15.2929 21.7071C15.1054 21.5196 15 21.2652 15 21V17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H15V11C15 10.7348 15.1054 10.4804 15.2929 10.2929C15.4804 10.1054 15.7348 10 16 10C16.2652 10 16.5196 10.1054 16.7071 10.2929C16.8946 10.4804 17 10.7348 17 11V15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16Z\" fill=\"#001024\" fill-opacity=\"0.5\"\/>\n                <\/svg>\n            <\/span>\n           \n            <span class=\"panel-title text-left\"\n                    :class=\"panelOpen ? 'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Qu\u2019est-ce que le criblage virtuel \u00e0 haut d\u00e9bit (vHTS) et pourquoi est-il important&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-6c3ae7238ed555421d05be5c98e7c201\" style=\"color:#475467\">Le criblage \u00e0 haut d\u00e9bit virtuel (vHTS) est une approche <em>in silico<\/em> qui permet de cribler rapidement des millions, voire des milliards de compos\u00e9s gr\u00e2ce \u00e0 des mod\u00e8les informatiques. Il offre une alternative compl\u00e9mentaire et \u00e9conomique \u00e0 l&rsquo;identification traditionnelle de mol\u00e9cules actives, acc\u00e9l\u00e9rant ainsi le processus de d\u00e9couverte de m\u00e9dicaments. <\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-0b3e95775605d2cb026a6b17c8d39bc8\"\n     :class=\"panelOpen ? 'Accordion__Panel--open' : ''\"\n     style=\"border-bottom-color:#f2e8d9;border-bottom-width:1px;   \">\n        <div class=\"Accordion__Title\">\n        <button type=\"button\" x-on:click=\"togglePanel()\" \n                class=\"w-full flex justify-start group relative items-center\" \n                style=\"color:#101828;\">\n           \n            <span class=\"mr-6\">\n                <svg x-show=\"panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewBox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16ZM29 16C29 18.5712 28.2376 21.0846 26.8091 23.2224C25.3807 25.3603 23.3503 27.0265 20.9749 28.0104C18.5995 28.9944 15.9856 29.2518 13.4638 28.7502C10.9421 28.2486 8.6257 27.0105 6.80762 25.1924C4.98953 23.3743 3.75141 21.0579 3.2498 18.5362C2.74819 16.0144 3.00563 13.4006 3.98957 11.0251C4.97351 8.64968 6.63975 6.61935 8.77759 5.1909C10.9154 3.76244 13.4288 3 16 3C19.4467 3.00364 22.7512 4.37445 25.1884 6.81163C27.6256 9.24882 28.9964 12.5533 29 16ZM27 16C27 13.8244 26.3549 11.6977 25.1462 9.88873C23.9375 8.07979 22.2195 6.66989 20.2095 5.83733C18.1995 5.00476 15.9878 4.78692 13.854 5.21136C11.7202 5.6358 9.76021 6.68345 8.22183 8.22183C6.68345 9.7602 5.63581 11.7202 5.21137 13.854C4.78693 15.9878 5.00477 18.1995 5.83733 20.2095C6.66989 22.2195 8.07979 23.9375 9.88873 25.1462C11.6977 26.3549 13.8244 27 16 27C18.9164 26.9967 21.7123 25.8367 23.7745 23.7745C25.8367 21.7123 26.9967 18.9164 27 16Z\" fill=\"#005DE5\"\/>\n                <\/svg>\n                <svg x-show=\"!panelOpen\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"32\" height=\"32\" viewBox=\"0 0 32 32\" fill=\"none\">\n                    <path d=\"M16 3C13.4288 3 10.9154 3.76244 8.77759 5.1909C6.63975 6.61935 4.97351 8.64968 3.98957 11.0251C3.00563 13.4006 2.74819 16.0144 3.2498 18.5362C3.75141 21.0579 4.98953 23.3743 6.80762 25.1924C8.6257 27.0105 10.9421 28.2486 13.4638 28.7502C15.9856 29.2518 18.5995 28.9944 20.9749 28.0104C23.3503 27.0265 25.3807 25.3603 26.8091 23.2224C28.2376 21.0846 29 18.5712 29 16C28.9964 12.5533 27.6256 9.24882 25.1884 6.81163C22.7512 4.37445 19.4467 3.00364 16 3ZM16 27C13.8244 27 11.6977 26.3549 9.88873 25.1462C8.07979 23.9375 6.66989 22.2195 5.83733 20.2095C5.00477 18.1995 4.78693 15.9878 5.21137 13.854C5.63581 11.7202 6.68345 9.7602 8.22183 8.22183C9.76021 6.68345 11.7202 5.6358 13.854 5.21136C15.9878 4.78692 18.1995 5.00476 20.2095 5.83733C22.2195 6.66989 23.9375 8.07979 25.1462 9.88873C26.3549 11.6977 27 13.8244 27 16C26.9967 18.9164 25.8367 21.7123 23.7745 23.7745C21.7123 25.8367 18.9164 26.9967 16 27ZM22 16C22 16.2652 21.8946 16.5196 21.7071 16.7071C21.5196 16.8946 21.2652 17 21 17H17V21C17 21.2652 16.8946 21.5196 16.7071 21.7071C16.5196 21.8946 16.2652 22 16 22C15.7348 22 15.4804 21.8946 15.2929 21.7071C15.1054 21.5196 15 21.2652 15 21V17H11C10.7348 17 10.4804 16.8946 10.2929 16.7071C10.1054 16.5196 10 16.2652 10 16C10 15.7348 10.1054 15.4804 10.2929 15.2929C10.4804 15.1054 10.7348 15 11 15H15V11C15 10.7348 15.1054 10.4804 15.2929 10.2929C15.4804 10.1054 15.7348 10 16 10C16.2652 10 16.5196 10.1054 16.7071 10.2929C16.8946 10.4804 17 10.7348 17 11V15H21C21.2652 15 21.5196 15.1054 21.7071 15.2929C21.8946 15.4804 22 15.7348 22 16Z\" fill=\"#001024\" fill-opacity=\"0.5\"\/>\n                <\/svg>\n            <\/span>\n           \n            <span class=\"panel-title text-left\"\n                    :class=\"panelOpen ? 'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Quelles sont les m\u00e9thodes de d\u00e9pistage virtuel propos\u00e9es par Sygnature&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-443fccbf9ae7397935513555ff2bd538\" style=\"color:#475467\">Nous proposons un criblage structural bas\u00e9 sur des donn\u00e9es cristallographiques ou des mod\u00e8les d&rsquo;homologie, ainsi qu&rsquo;un criblage bas\u00e9 sur les ligands utilisant des pharmacophores, la similarit\u00e9 forme-\u00e9lectrostatique et les empreintes digitales des ligands. Ces m\u00e9thodes permettent d&rsquo;enrichir les corpus de compos\u00e9s pour un potentiel de hit accru. <\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-9912a86bf0c4fa63dfb40845b6bba639\"\n     :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Comment Sygnature g\u00e8re-t-elle les campagnes de d\u00e9pistage \u00e0 grande \u00e9chelle&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-6f8f5249afd918cd5c29f05a1887c3d6\" style=\"color:#475467\">Gr\u00e2ce \u00e0 l&rsquo;acc\u00e8s \u00e0 AWS et \u00e0 notre HPC interne, nous pouvons ex\u00e9cuter en toute s\u00e9curit\u00e9 des projets vHTS impliquant des milliards de compos\u00e9s en quelques heures, en tirant parti de plateformes comme OpenEye Orion pour le criblage \u00e0 l&rsquo;\u00e9chelle du giga-\u00e9chelle.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-3bcb75d8b0cab0e60090b7eb58894e89\"\n     :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Quels sont les facteurs qui d\u00e9terminent le succ\u00e8s d&rsquo;une campagne de projection virtuelle&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-8e48d70ba41a9a0edcbf8e2e9d41b243\" style=\"color:#475467\">Des compos\u00e9s chimiques de haute qualit\u00e9, des m\u00e9thodes de criblage robustes et des mod\u00e8les structuraux pr\u00e9cis&nbsp;: Sygnature garantit ces atouts gr\u00e2ce \u00e0 des biblioth\u00e8ques de compos\u00e9s soigneusement s\u00e9lectionn\u00e9es, des \u00e9chafaudages propri\u00e9taires et des flux de travail valid\u00e9s. <\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-c98bf8d15a182bb5a4aad08a57318288\"\n     :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Sygnature propose-t-il un suivi apr\u00e8s utilisation&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-72b9f7fa737be67980393b9fdcd82876\" style=\"color:#475467\">Oui. Notre \u00e9quipe exp\u00e9riment\u00e9e en chimie computationnelle analyse les donn\u00e9es vHTS, s\u00e9lectionne les compos\u00e9s \u00e0 acheter ou \u00e0 synth\u00e9tiser et se coordonne avec des fournisseurs de confiance pour livrer les compos\u00e9s destin\u00e9s au criblage <em>in vitro<\/em> en quelques semaines. <\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div x-data=\"accordionPanel(0, '', false)\"\n     class=\"Accordion__Panel mb-2 wp-elements-efc74bd21520e57bfc7ef5ab9f082770\"\n     :class=\"panelOpen ? 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'panel-title-open' : 'text-[#101828]'\">\n                    <p class=\"has-text-2-xl-font-size\">Quels sont les principaux avantages d&rsquo;un partenariat avec Sygnature pour le d\u00e9pistage virtuel&nbsp;?<\/p>\n\n                <\/span>\n        <\/button>\n    <\/div>\n    \n        <div class=\"Accordion__Content\" x-show=\"panelOpen\" x-collapse>\n        <div style=\"\">\n            <div class=\"acf-innerblocks-container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-color has-link-color wp-elements-11f6f55f0fddef5bf8c761cf81837cfd\" style=\"color:#475467\">S\u2019associer \u00e0 Sygnature, c\u2019est d\u00e9couvrir des hits plus rapidement et plus intelligemment gr\u00e2ce \u00e0 une expertise consid\u00e9rable&nbsp;:<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color wp-elements-e1ef79e96b8221b01022a14ffbdd46cc\"><strong>Rapidit\u00e9 :<\/strong> Analysez des milliards de compos\u00e9s en quelques heures seulement gr\u00e2ce \u00e0 des plateformes HPC et cloud avanc\u00e9es.<\/p>\n\n\n\n<p class=\"has-grey-600-color has-text-color has-link-color wp-elements-f19bfd6cf03bfe7c9018b0a24bde8e2b\"><strong>Diversit\u00e9 :<\/strong> Acc\u00e9dez \u00e0 des biblioth\u00e8ques commerciales organis\u00e9es et \u00e0 des collections exclusives pour une couverture maximale de l&rsquo;espace chimique.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-8f88edc9a98e2ee88affb68ddfee615c\" style=\"color:#475467\"><strong>Robustesse<\/strong> : B\u00e9n\u00e9ficiez de flux de travail int\u00e9gr\u00e9s, d&rsquo;un triage en plusieurs \u00e9tapes et d&rsquo;un r\u00e9ajustement de haut niveau pour des r\u00e9sultats fiables qui peuvent \u00eatre r\u00e9ajust\u00e9s par amarrage et\/ou raffinement des alignements de ligands \u00e0 l&rsquo;aide de niveaux de th\u00e9orie plus \u00e9lev\u00e9s.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-d3feae1a66852e6247f69b7084b94758\" style=\"color:#475467\"><strong>Expertise :<\/strong> Collaborez avec plus de 20 sp\u00e9cialistes qui combinent des connaissances en chimie computationnelle et m\u00e9dicinale, appuy\u00e9es par de nombreuses \u00e9tudes de cas couvrant diverses classes cibles.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-aa5fa936912dcc1a1c212771432d50ee\" style=\"color:#475467\"><\/p>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n<\/div>\n    <\/div>\n    \n            <\/section><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-15 is-position-sticky\" style=\"   \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Solutions connexes<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e17f75369917380307a8227af22f62bc\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d&rsquo;experts chevronn\u00e9s de l&rsquo;industrie pharmaceutique du monde entier, garantissant l&rsquo;excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Structure-Based Drug Design\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/Structure-Based-Drug-Design.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-935cbd7616b9aa7bec1f6068f0efc491\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/structure-based-drug-design\/\">Conception de m\u00e9dicaments bas\u00e9e sur la structure<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e3c3fd7ce9b129aa16f8cb5cff3d29bc\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Nous vous aidons \u00e0 concevoir de meilleurs compos\u00e9s avec une plus grande confiance. Gr\u00e2ce \u00e0 des connaissances \u00e0 l&rsquo;\u00e9chelle quantique et \u00e0 des simulations dynamiques, nous pr\u00e9disons l&rsquo;affinit\u00e9, guidons l&rsquo;optimisation et vous aidons \u00e0 identifier plus rapidement les candidats les plus prometteurs. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/computer-aided-drug-design\/structure-based-drug-design\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Ligand-Based-Drug-Discovery-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Ligand-Based-Drug-Discovery.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Ligand Based Drug Discovery\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Ligand-Based-Drug-Discovery.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Ligand-Based-Drug-Discovery-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Ligand-Based-Drug-Discovery.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-5306d3520b5b3c8aa6708aab286d04a8\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/\" type=\"page\" id=\"1519\">Conception de m\u00e9dicaments bas\u00e9e sur les ligands<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e7276f6cdc6b4d50290c46b2e50330ac\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Exploiter les propri\u00e9t\u00e9s de mol\u00e9cules actives connues pour g\u00e9n\u00e9rer et optimiser rapidement de nouveaux compos\u00e9s gr\u00e2ce \u00e0 des connaissances bas\u00e9es sur les ligands, des outils aliment\u00e9s par l&rsquo;IA et une expertise collaborative afin de d\u00e9couvrir de nouveaux espaces chimiques et d&rsquo;acc\u00e9l\u00e9rer les d\u00e9couvertes.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-medicaments-basee-sur-des-ligands\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-768x433.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-1024x577.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics.webp 1065w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x360.webp 640w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x361.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"3D molecular visualization representing diverse therapeutic modalities in drug discovery, including PROTACs, molecular glues, peptides, and RNA-targeting therapies.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTA2NSIgaGVpZ2h0PSI2MDAiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-300x169.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-768x433.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-1024x577.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics.webp 1065w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x360.webp 640w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/multimodal-drug-discovery-protacs-molecular-glues-biologics-640x361.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-a22e0e982c407badd8c8c322816bd077\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Modalit\u00e9s<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-3b23b8a1af20c444c8f504df6edcc1c1\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Fournir une approche int\u00e9gr\u00e9e et ind\u00e9pendante des modalit\u00e9s de d\u00e9couverte de m\u00e9dicaments pour aborder la biologie complexe, acc\u00e9l\u00e9rer le d\u00e9veloppement et faire progresser les th\u00e9rapies innovantes en toute confiance.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/modalites\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"High Throughput Screening\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/High-Throughput-Screening.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-ee47efcfe0922214ae246b4562f55da1\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">criblage \u00e0 haut d\u00e9bit<\/a><\/h3>\n\n\n\n<p>Identification int\u00e9gr\u00e9e de cibles th\u00e9rapeutiques utilisant le criblage \u00e0 haut d\u00e9bit, le criblage de fragments et une automatisation avanc\u00e9e, fournissant des points de d\u00e9part de haute qualit\u00e9 pour une d\u00e9couverte de m\u00e9dicaments r\u00e9ussie.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/biosciences\/criblage-a-haut-debit\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-ed8e509d wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" \n         class=\"Media full-width w-full\"\n         style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Image showing a grid of chemical structures representing strategically designed libraries for SAR investigations, supporting lead optimization and innovative compound synthesis.\" loading=\"lazy\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTI1MSIgaGVpZ2h0PSI2NjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-300x159.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-768x408.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-1024x544.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation.webp 1251w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/library-design-chemical-structures-sar-investigation-640x340.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-67878564ebb21864e813254dcc9b4a32\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Conception de biblioth\u00e8que<\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-1293c3918f352aae527b8a308cafdc46\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Conception de biblioth\u00e8ques de compos\u00e9s diversifi\u00e9es et pr\u00eates pour la synth\u00e8se gr\u00e2ce \u00e0 des techniques de calcul avanc\u00e9es afin d&rsquo;acc\u00e9l\u00e9rer la d\u00e9couverte de compos\u00e9s actifs et de permettre une optimisation innovante des t\u00eates de s\u00e9rie.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/conception-de-medicaments-assistee-par-ordinateur\/conception-de-la-bibliotheque\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":9764,"parent":16400,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-4364","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Criblage virtuel - D\u00e9couverte de m\u00e9dicaments - D\u00e9couverte de signatures<\/title>\n<meta name=\"description\" content=\"Identification ultra-rapide de compos\u00e9s actifs gr\u00e2ce au criblage virtuel, avec nos techniques in silico avanc\u00e9es et nos biblioth\u00e8ques de compos\u00e9s soigneusement s\u00e9lectionn\u00e9es.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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