{"id":4344,"date":"2025-11-18T13:34:32","date_gmt":"2025-11-18T13:34:32","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/domaines-therapeutiques\/oncologie\/"},"modified":"2026-02-13T09:11:03","modified_gmt":"2026-02-13T09:11:03","slug":"oncologie","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/","title":{"rendered":"Oncologie"},"content":{"rendered":"\n<div x-data='subNav({\"anchor_map\":{\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/domaines-therapeutiques\\\/oncologie\\\/\":\"Oncologie et immuno-oncologie\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/inflammation-et-immunologie\\\/\":\"Inflammation et immunologie\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/domaines-therapeutiques\\\/neurosciences\\\/\":\"Neuroscience\",\"https:\\\/\\\/www.sygnaturediscovery.com\\\/fr\\\/domaines-therapeutiques\\\/maladies-metaboliques\\\/\":\"Maladies m\\u00e9taboliques\"}})' id=\"pegasus-subnav\" class=\"SubNav w-full text-content-tertiary \" false x-cloak style=\"\">\n    <div x-ref=\"fixedNav\" class=\"SubNav__bar w-full h-[var(--subnav-height)] z-page-header whitespace-nowrap border-t border-grey-200 container flex items-center justify-between shadow-sm\">\n\n                    <!-- Desktop Navigation (tablet and up) -->\n            <div class=\"flex items-center min-w-0 flex-1 mr-4\">\n                                    <div class=\"flex items-center gap-x-3 mr-4 sm:mr-8 pr-4 sm:pr-8 md:border-r md:border-grey-200 flex-shrink-0\">\n                        \n                                                    <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/\" class=\"wp-block-button wp-block-button is-style-back-chevron text-content-primary \">\n                                <span class=\"wp-block-button__link wp-element-button bg-ivory-300 text-content-primary rounded-full\">Domaines th\u00e9rapeutiques<\/span>\n                            <\/a>\n                                            <\/div>\n                \n                <div class=\"hidden md:block min-w-0 flex-1 overflow-hidden relative\">\n                    <div class=\"nav-container-wrapper\">\n                        <ul x-ref=\"navList\" class=\"flex flex-row items-center !m-0 !list-none gap-8 !py-4 overflow-x-auto scrollbar-hide pr-16\">\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/' === window.location.href ? '-active' : ''\">\n                                            Oncologie et immuno-oncologie\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/inflammation-et-immunologie\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/inflammation-et-immunologie\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/inflammation-et-immunologie\/' === window.location.href ? '-active' : ''\">\n                                            Inflammation et immunologie\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/neurosciences\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/neurosciences\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/neurosciences\/' === window.location.href ? '-active' : ''\">\n                                            Neuroscience\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                            <li class=\"!m-0 !p-0 !list-none flex-shrink-0\">\n                                    <div class=\"wp-block-button is-style-text-link\">\n                                        <a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/maladies-metaboliques\/\" class=\"wp-block-button__link wp-element-button has-text-sm-font-size px-2 whitespace-nowrap after:bg-transparent \" :class=\"currentLink === 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/maladies-metaboliques\/' || 'https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/maladies-metaboliques\/' === window.location.href ? '-active' : ''\">\n                                            Maladies m\u00e9taboliques\n                                        <\/a>\n                                    <\/div>\n                                <\/li>\n                                                    <\/ul>\n                        \n                        <div x-ref=\"scrollIndicator\" class=\"scroll-indicator\" x-show=\"showScrollIndicator\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0 transform translate-x-full\" x-transition:enter-end=\"opacity-100 transform translate-x-0\">\n                            <svg class=\"chevron-icon w-4 h-4\" viewbox=\"0 0 16 16\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" aria-hidden=\"true\">\n                                <path d=\"M5.65306 3.53025L10.6531 8.53025C10.7227 8.60018 10.7775 8.68297 10.8154 8.77414C10.8533 8.8653 10.8735 8.96304 10.8735 9.06175C10.8735 9.16046 10.8533 9.2582 10.8154 9.34936C10.7775 9.44053 10.7227 9.52332 10.6531 9.59325L5.65306 14.5932C5.51217 14.7341 5.32107 14.8133 5.12181 14.8133C4.92255 14.8133 4.73145 14.7341 4.59056 14.5932C4.44966 14.4523 4.37051 14.2612 4.37051 14.062C4.37051 13.8627 4.44966 13.6716 4.59056 13.5307L9.06294 9.06175L4.59056 4.59325C4.44966 4.45236 4.37051 4.26126 4.37051 4.062C4.37051 3.86274 4.44966 3.67164 4.59056 3.53075C4.73145 3.38985 4.92255 3.3107 5.12181 3.3107C5.32107 3.3107 5.51217 3.38985 5.65306 3.53075V3.53025Z\" fill=\"currentColor\"><\/path>\n                            <\/svg>\n                        <\/div>\n                    <\/div>\n                <\/div>\n            <\/div>\n\n            <!-- Mobile menu button -->\n            <button x-ref=\"navMenuButton\" type=\"button\" class=\"flex justify-center items-center py-2 whitespace-nowrap pl-5 pr-2.5 ml-auto md:hidden\" aria-label=\"Show more navigation items\" :aria-expanded=\"mobileSubMenuOpen\">\n                <span class=\"sr-only pr-2 inline-block\">More<\/span>\n\n                <svg class=\"transition duration-500 ease-in-out\" :class=\"mobileSubMenuOpen ? 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'bg-blue-50 text-blue-700 font-medium' : ''\" false>\n                                        Maladies m\u00e9taboliques\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n<section class=\"BackgroundEffectWrapper w-full relative is-layout-flow wp-block-pegasus-background-effect-is-layout-flow\" style=\"background-color:var(--wp--preset--color--ivory-300);\">\n\n            <div class=\"BackgroundEffect positioning-relative\" style=\" --translate-y: 6rem;\" x-data=\"backgroundEffect()\" x-init='initBackgroundEffect({\"type\":\"page-background-effect\",\"enableEffect\":true,\"backgroundStyle\":\"background-2\",\"positioningMode\":\"relative\",\"waveOffsetX\":0,\"waveOffsetY\":0,\"enableParallax\":true,\"interactionMode\":\"none\",\"continuousAnimation\":false,\"animationSpeed\":1,\"entrance\":\"up\",\"translateY\":\"6rem\",\"svgUrl\":\"https:\\\/\\\/www.sygnaturediscovery.com\\\/wp-content\\\/themes\\\/pegasus\\\/blocks\\\/BackgroundEffect\\\/assets\\\/background-2.svg\",\"fadeOnScroll\":true,\"singleRunDuration\":0.1}, false)' x-cloak>\n        \n                <div class=\"BackgroundEffect__svg-layer\" style=\"opacity: 0;\">\n            <div class=\"BackgroundEffect__svg-container\">\n                <img data-svg-url=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/themes\/pegasus\/blocks\/BackgroundEffect\/assets\/background-2.svg\" alt=\"Background\" class=\"BackgroundEffect__svg\">\n            <\/div>\n        <\/div>\n        \n                <canvas class=\"BackgroundEffect__canvas\" x-ref=\"canvas\"><\/canvas>\n    <\/div>\n\n        <div class=\"BackgroundEffectWrapper__content relative z-20 h-full parallax-content\">\n        <div class=\"inner relative h-full w-full\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--100); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-center is-layout-constrained wp-container-core-group-is-layout-1c0a22d9 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--90);padding-left:var(--wp--preset--spacing--90)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center is-style-tag has-text-color has-link-color has-tag-style wp-elements-6b72bab57b47c87cb5db6dbdea989fc1\" style=\"color:#002b46;margin-top:0;margin-bottom:0;--paragraph-dot-color:#005DE5\">domaines th\u00e9rapeutiques<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center has-text-5-xl-font-size\" style=\"font-style:normal;font-weight:300\">Oncologie et immuno-oncologie<\/h1>\n\n\n\n<p class=\"has-text-align-center has-text-color has-link-color has-text-lg-font-size wp-elements-60893816b47a990ede1ac3ef55f15f19\" style=\"color:#002b46;font-style:normal;font-weight:400\">Sygnature Discovery r\u00e9unit une expertise de renomm\u00e9e mondiale pour acc\u00e9l\u00e9rer la d\u00e9couverte de m\u00e9dicaments en oncologie, de la validation des cibles aux \u00e9tudes cliniques. Notre \u00e9quipe dirigeante combine une exp\u00e9rience issue des secteurs pharmaceutique, biotechnologique, associatif et universitaire afin de vous proposer une r\u00e9flexion strat\u00e9gique et des solutions innovantes pour votre projet. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-bb659de6 wp-block-buttons-is-layout-flex\" style=\"margin-top:var(--wp--preset--spacing--50)\">\n<div class=\"wp-block-button\" modaltype=\"side\" data-pegasus-modal=\"Modal--side\"><a data-pegasus-modal=\"Modal--Side\" class=\"wp-block-button__link has-text-align-center wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light columns-grid mobile-stacking-standard   four-column-counters is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --column-tablet-columns: 2;--column-tablet-rows: 2; padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--70); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-columns has-text-dark-primary-color has-text-color has-link-color wp-elements-7789fdcc2820b1436bebce15c7b8b2b9 is-layout-flex wp-container-core-columns-is-layout-f3a7ff92 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-119bc444 wp-block-column-is-layout-flow\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div x-data=\"CounterBlock()\" x-ref=\"theCounter\" x-intersect.once.half=\"startRoll()\" data-number=\"13\" data-thousands-separator=\"\" data-decimal-separator=\"\" class=\"Counter transform transition duration-1000 wp-elements-de47afc240b5c1a39f03b2e6f6b0fe9e  has-text-5-xl-font-size mb-2\" style=\"font-style:normal;font-weight:400; color:#002b46;\">\n\n    \n    <div class=\"Counter__inner flex justify-center\">\n                        \n                            <span class=\"Counter__number block whitespace-nowrap\" x-ref=\"number\">\n\n                                                                                        <span class=\"counter-digit-wrapper relative inline-block\">\n                                <span class=\"invisible inline-block\">1<\/span>\n                                <span class=\"absolute left-0 top-0 flex flex-col transition-transform duration-1000 ease-[cubic-bezier(.42,.08,.04,1)] counter-digit-stack\" :data-stack-index=\"0\" x-data=\"CounterDigit(0)\" :style=\"'transform: translateY(calc(-' + digitOffsets[0] + ' * var(--counter-digit-height, 1.5em)))'\">\n\n                                    <template x-for=\"n in digitStacks[0]\" :key=\"n.key\">\n                                        <span x-text=\"n.val\"><\/span>\n                                    <\/template>\n                                <\/span>\n                            <\/span>\n                                                                                                <span class=\"counter-digit-wrapper relative inline-block\">\n                                <span class=\"invisible inline-block\">3<\/span>\n                                <span class=\"absolute left-0 top-0 flex flex-col transition-transform duration-1000 ease-[cubic-bezier(.42,.08,.04,1)] counter-digit-stack\" :data-stack-index=\"1\" x-data=\"CounterDigit(1)\" :style=\"'transform: translateY(calc(-' + digitOffsets[1] + ' * var(--counter-digit-height, 1.5em)))'\">\n\n                                    <template x-for=\"n in digitStacks[1]\" :key=\"n.key\">\n                                        <span x-text=\"n.val\"><\/span>\n                                    <\/template>\n                                <\/span>\n                            <\/span>\n                                                            \n                <!-- Suffix -->\n                <template x-if=\"suffixText\">\n                    <span class=\"inline-block\" x-text=\"suffixText\"><\/span>\n                <\/template>\n\n            <\/span>\n                \n                            <\/div>\n\n    <\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-8476b90a wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center has-text-color has-link-color has-text-sm-font-size wp-elements-5b6b4dd6e8430f960a931f4744f9d8d2\" style=\"color:#00102480\">candidats en oncologie<br> Livraison en cours.<br> essais cliniques humains<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-119bc444 wp-block-column-is-layout-flow\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div x-data=\"CounterBlock()\" x-ref=\"theCounter\" x-intersect.once.half=\"startRoll()\" data-number=\"7\" data-thousands-separator=\"\" data-decimal-separator=\"\" class=\"Counter transform transition duration-1000 wp-elements-bc389d21f1a5c43d35cfb9f01b6a1b75  has-text-5-xl-font-size mb-2\" style=\"font-style:normal;font-weight:400; color:#002b46;\">\n\n    \n    <div class=\"Counter__inner flex justify-center\">\n                        \n                            <span class=\"Counter__number block whitespace-nowrap\" x-ref=\"number\">\n\n                                                                                        <span class=\"counter-digit-wrapper relative inline-block\">\n                                <span class=\"invisible inline-block\">7<\/span>\n                                <span class=\"absolute left-0 top-0 flex flex-col transition-transform duration-1000 ease-[cubic-bezier(.42,.08,.04,1)] counter-digit-stack\" :data-stack-index=\"0\" x-data=\"CounterDigit(0)\" :style=\"'transform: translateY(calc(-' + digitOffsets[0] + ' * var(--counter-digit-height, 1.5em)))'\">\n\n                                    <template x-for=\"n in digitStacks[0]\" :key=\"n.key\">\n                                        <span x-text=\"n.val\"><\/span>\n                                    <\/template>\n                                <\/span>\n                            <\/span>\n                                                            \n                <!-- Suffix -->\n                <template x-if=\"suffixText\">\n                    <span class=\"inline-block\" x-text=\"suffixText\"><\/span>\n                <\/template>\n\n            <\/span>\n                \n                            <\/div>\n\n    <\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-8476b90a wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center has-text-color has-link-color has-text-sm-font-size wp-elements-d59e62cabaa81ee17b4a7a4d0a445f96\" style=\"color:#00102480\">Autres compos\u00e9s<br> avanc\u00e9 dans le pr\u00e9-<br> d\u00e9veloppement clinique<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-119bc444 wp-block-column-is-layout-flow\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-8476b90a wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-center has-text-color has-link-color has-text-lg-font-size wp-elements-0652355c025ab98a0de3ae4b677dbdd9\" style=\"color:#00102480\">Expertise couvrant les cibles traditionnelles et \u00e9mergentes, notamment les petites mol\u00e9cules, les d\u00e9gradeurs et les ADC.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n<div style=\"height:4vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div>\n    <\/div>\n<\/section>\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-1 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-12dd3699 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-aa44ba95d7be2dff44c637536503b178\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group children-fill-width is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Les traitements anticanc\u00e9reux modernes ciblant des mutations pr\u00e9cises ont transform\u00e9 le pronostic des patients, mais les r\u00e9missions \u00e0 long terme restent rares.  <\/h2>\n\n\n\n<p style=\"padding-bottom:var(--wp--preset--spacing--20)\">Nos scientifiques interviennent sur l\u2019ensemble du spectre de la d\u00e9couverte en oncologie, de l\u2019identification des cibles et de l\u2019optimisation des compos\u00e9s candidats \u00e0 leur s\u00e9lection et \u00e0 leur positionnement clinique. Des \u00e9quipes int\u00e9gr\u00e9es de chimistes m\u00e9dicinaux, d\u2019experts en DMPK, de bioscientifiques et de sp\u00e9cialistes <em>in vivo<\/em> collaborent pour d\u00e9velopper des th\u00e9rapies de pointe. <\/p>\n\n\n\n<div style=\"margin-top:var(--wp--preset--spacing--60)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-aspect-ratio aspect-59x35 has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-300x210.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-768x538.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-1024x717.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-514x360.webp 514w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-640x448.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Illustration de cellules canc\u00e9reuses au grossissement, repr\u00e9sentant la d\u00e9couverte de m\u00e9dicaments en oncologie et les th\u00e9rapies cibl\u00e9es.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-300x210.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-768x538.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-1024x717.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-514x360.webp 514w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/oncology-drug-discovery-640x448.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-cbe57604 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--100)\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Progress Progress--left Progress--scroll absolute z-[1000]\" style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--ivory-300); --progress-background: rgba(249, 242, 232, 0.2);\" x-data=\"progress()\" x-init='init({\"position\":\"left\",\"eventType\":\"scroll\",\"scrollOptions\":{\"scroll_target\":\"m\\u00e8re\",\"container_selector\":\"\"},\"tickerOptions\":[],\"formOptions\":[],\"anchorPoints\":{\"align_points\":true,\"points\":[{\"element_id\":\"\\u00e9l\\u00e9ment-collant-1\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-2\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-3\",\"label\":\"\"}]},\"showEndDot\":true,\"containerScrollOffset\":0.2,\"progressThreshold\":0.005})' x-cloak data-position=\"left\" data-event-type=\"scroll\">\n    <div class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\" x-ref=\"fill\"><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-d2c5c54a wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-6752e3ba wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/#sticky-item-1\">Notre philosophie en mati\u00e8re de d\u00e9couverte de m\u00e9dicaments en oncologie<\/a><\/h2>\n\n\n\n<p><strong>Les patients au c\u0153ur de chaque projet.<\/strong><\/p>\n\n\n\n<p>Le cancer n\u2019est plus consid\u00e9r\u00e9 comme une maladie unique. Nos scientifiques collaborent avec des experts en inflammation, immunologie et neurologie afin d\u2019acc\u00e9l\u00e9rer la mise au point de m\u00e9dicaments candidats, notamment pour les projets d\u2019immuno-oncologie et de recherche sur les cancers du syst\u00e8me nerveux central. Nous concevons des protocoles de criblage <em>in vitro<\/em> robustes et personnalis\u00e9s, s\u2019appuyant sur des technologies de pointe et des plateformes de biophysique orthogonales pour obtenir rapidement des donn\u00e9es exploitables. Notre banque de sang de donneurs humains interne facilite l\u2019acc\u00e8s aux cellules immunitaires et inflammatoires pour la recherche en immuno-oncologie.   <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-2\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/#sticky-item-2\">Pourquoi choisir Sygnature Discovery en oncologie ?<\/a><\/h2>\n\n\n\n<p>Notre vaste exp\u00e9rience en mati\u00e8re de d\u00e9couverte de m\u00e9dicaments oncologiques et notre base de connaissances collective \u00e9clairent les d\u00e9cisions strat\u00e9giques. Ces derni\u00e8res ann\u00e9es, cette expertise a permis de d\u00e9velopper treize candidats cliniques en oncologie (essais cliniques de phases 1 \u00e0 3) et sept autres en d\u00e9veloppement pr\u00e9clinique. <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-2\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-3ae50e87 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--70);padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--100)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/decouverte-integree-de-medicaments\/#sticky-item-2\">Oncologie translationnelle<\/a><\/h2>\n\n\n\n<p>Notre \u00e9quipe d\u2019oncologie translationnelle con\u00e7oit et r\u00e9alise des \u00e9tudes pr\u00e9cliniques personnalis\u00e9es selon diff\u00e9rentes modalit\u00e9s, notamment les petites mol\u00e9cules, les produits biologiques, les ADC, les th\u00e9rapies \u00e0 base d\u2019ARN\/ADN, les th\u00e9rapies virales et cellulaires et la radioth\u00e9rapie.<\/p>\n\n\n\n<p>Nous proposons des mod\u00e8les tumoraux valid\u00e9s et personnalis\u00e9s, incluant des syst\u00e8mes x\u00e9nogreff\u00e9s, syng\u00e9niques, orthotopiques et humanis\u00e9s, avec des capacit\u00e9s couvrant la monoth\u00e9rapie, la th\u00e9rapie combin\u00e9e, la mod\u00e9lisation de la r\u00e9sistance et l\u2019optimisation des doses et des sch\u00e9mas d\u2019administration. Ces \u00e9tudes <em>in vivo<\/em> sont compl\u00e9t\u00e9es par des plateformes <em>ex vivo<\/em> permettant une analyse d\u00e9taill\u00e9e des biomarqueurs, l\u2019\u00e9tude de l\u2019interaction avec la cible et le profilage des cellules immunitaires. De plus, nous pouvons enrichir ces \u00e9tudes par l\u2019imagerie <em>in vivo<\/em> ou r\u00e9aliser des combinaisons <em>in vitro<\/em> et <em>in vivo<\/em> avec irradiation ionisante.  <\/p>\n\n\n\n<p>En int\u00e9grant les donn\u00e9es d\u2019efficacit\u00e9, de pharmacocin\u00e9tique, de pharmacodynamique et de biomarqueurs, nous \u00e9tablissons des relations claires qui r\u00e9duisent les risques li\u00e9s \u00e0 votre portefeuille de produits et acc\u00e9l\u00e8rent les progr\u00e8s.<\/p>\n<\/div>\n\n\n<section class=\"Pegasus__Container w-full hidden sm:block  relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100)\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":true,\"element\":\"autre\",\"elementId\":\"\\u00e9l\\u00e9ment-collant-1\",\"action\":\"vue\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/2388101fa65b780860e4f2dd073cddd2274da68c-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/2388101fa65b780860e4f2dd073cddd2274da68c.webp 509w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"509\" height=\"339\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/2388101fa65b780860e4f2dd073cddd2274da68c.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/2388101fa65b780860e4f2dd073cddd2274da68c-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/2388101fa65b780860e4f2dd073cddd2274da68c.webp 509w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"561\" height=\"588\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-87beb0d0 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2a411371 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Notre expertise en modalit\u00e9s th\u00e9rapeutiques<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-a511f284db70aa2b3729b23363441847\" style=\"color:#001024b3\">Faites progresser vos programmes avec<br> L\u2019expertise de Sygnature Discovery en<br> conjugu\u00e9s anticorps-m\u00e9dicament et<br> D\u00e9gradation cibl\u00e9e des prot\u00e9ines.<br> Nos \u00e9quipes int\u00e9gr\u00e9es se combinent<br> connaissance biologique approfondie, innovante<br> chimie et connaissances translationnelles<br> comment faire progresser votre oncologie<br> programmer efficacement.<\/p>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-dba583183441a4533dfcd38d04a1b202\" style=\"color:#001024b3\"><\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-e74d460a wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Graphique illustrant la plateforme NewPath ADC pour le d\u00e9veloppement de conjugu\u00e9s anticorps-m\u00e9dicament de nouvelle g\u00e9n\u00e9ration, combinant un ciblage de pr\u00e9cision et des strat\u00e9gies de charge utile haute performance.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/antibody-drug-conjugates-adc-development-targeted-cancer-therapy.jpg\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-dfe6b5b43537402ce83737164955cd35\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Conjugu\u00e9s anticorps-m\u00e9dicament (ADC)<\/h2>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"side\"><a class=\"wp-block-button__link wp-element-button\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-f7b5deab wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--45);padding-bottom:var(--wp--preset--spacing--45); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-300x120.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-768x308.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-1024x410.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-640x256.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"1500\" height=\"601\" class=\"image-original \" alt=\"Visualisation mol\u00e9culaire 3D illustrant la d\u00e9gradation cibl\u00e9e des prot\u00e9ines \u00e0 l'aide du syst\u00e8me ubiquitine-prot\u00e9asome pour \u00e9liminer les prot\u00e9ines li\u00e9es \u00e0 la maladie.\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTUwMCIgaGVpZ2h0PSI2MDEiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-300x120.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-768x308.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-1024x410.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery.webp 1500w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/targeted-protein-degradation-ubiquitin-proteasome-drug-discovery-640x256.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-fe9cc265 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-3ae01579e46c02648354e208bd7f4c0b\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\">Colles et d\u00e9gradeurs mol\u00e9culaires<\/h2>\n\n\n\n<p><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/modalites\/degradation-ciblee-des-proteines\/\">Apprendre encore plus<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-f51b47c1 wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--90)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-8d8df379f43e7bb730e4a7199e3a9035 wp-container-content-1d651e7a\" style=\"color:#002b46\">Notre consultant principal en oncologie<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">    <section class=\"FeaturedPostGrid\">\n        <div class=\"FeaturedPostGrid__container\">\n                            <div class=\"FeaturedPost add-background-image bg-ivory-300 flex flex-col md:flex-row items-stretch gap-8 rounded-3xl\">\n    <div class=\"flex-1 flex flex-col justify-between gap-6 p-[clamp(2rem,3vw,4rem)]\">\n        <div class=\"flex flex-col\">\n            <h2 class=\"wp-block-heading has-text-4-xl-font-size text-dark-blue-700 !mb-0\">Allan Jordan, PhD<\/h2>\n                            <p class=\"has-text-4-xl-font-size text-[#00102480] mb-10\">Vice President, Oncology Drug Discovery<\/p>\n                                        <div class=\"text-[#001024B2] has-text-base-font-size has-heading-font-family max-w-[560px]\">\n                    Allan joined Sygnature Discovery in February 2019 and serves as Vice President of Oncology Drug Discovery. With more than 25 years of experience in medicinal chemistry and drug discovery, Allan has an outstanding track record of advancing compounds into clinical trials across multiple therapeutic areas. Before joining Sygnature, he spent nine years as Head of Chemistry at the Cancer Research UK Manchester Institute Drug Discovery Unit. During his time at\u2026\n                <\/div>\n                    <\/div>\n\n        <div class=\"wp-block-buttons is-layout-flex items-center gap-6 pt-2\">\n            <div class=\"wp-block-button btn-primary\">\n                <a class=\"wp-block-button__link wp-element-button \" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/people\/dr-allan-jordan\/\" data-pegasus-modal=\"Modal--team\">View profile<\/a>\n            <\/div>\n                            <div class=\"wp-block-button is-style-text-link\">\n                    <a class=\"wp-block-button__link wp-element-button \" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/a-propos-de-nous\/notre-equipe\/\" target=\"_self\">Homepage<\/a>\n                <\/div>\n                    <\/div>\n    <\/div>\n\n    <div class=\"md:w-1\/2 w-full relative p-6\">\n                            <div class=\"w-full h-0 pb-[73%] relative overflow-hidden rounded-2xl\">\n                <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-300x218.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-768x557.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1.webp 820w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-496x360.webp 496w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-640x464.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"820\" height=\"595\" class=\"absolute inset-0 w-full h-full object-cover rounded-2xl\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iODIwIiBoZWlnaHQ9IjU5NSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-300x218.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-768x557.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1.webp 820w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-496x360.webp 496w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/BAD_Allan-Jordan_VP_Oncology_UK-1-640x464.webp 640w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n            <\/div>\n            <\/div>\n<\/div>\n\n\n\n                    <\/div>\n    <\/section>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit overflow-hidden text-content-dark mobile-stacking-standard   left-aligned-multi-slide-carousel is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--70);padding-bottom:var(--wp--preset--spacing--50); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section x-data='newcarousel({\"transition\":\"slide\",\"overflow\":false,\"autoplay\":0,\"infinite\":false,\"preview\":false,\"slidesInView\":1.75,\"slidesInViewTablet\":1,\"slidesInViewMobile\":1.15,\"slideGap\":0,\"align\":\"left\",\"swipeScroll\":false,\"snapToSlides\":false})' x-intersect.once=\"initAutoplay()\" class=\"Content__Carousel wp-elements-394492d8454161fd722965729e8fc65f relative h-full\" style=\"--slides-to-show-desktop: 1.75; --slides-to-show-tablet: 1; --slides-to-show-mobile: 1.15; --slide-gap: 0px; --carousel-arrow-spacing: 50%; --carousel-arrow-inset: 0rem; padding-top:0;padding-bottom:var(--wp--preset--spacing--60);;\">\n            \n    <div class=\"Carousel__WrapperOuter relative z-10\" data-carousel-anchor style=\"--carousel-arrow-spacing: %; --carousel-arrow-inset: rem\">\n\n                    <div class=\"pb-10 intro-text-wrapper\">\n                <div class=\"flex flex-col md:flex-row relative\">\n                    <div class=\"Carousel__introText mb-16 md:mb-0 w-full md:w-[45%] text-left md:max-w-[708px]\">\n                        <p class=\"has-text-align-center is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style\" style=\"padding-bottom: var(--wp--preset--spacing--30); color: rgba(0, 16, 36, 0.7); padding-right: 0px; padding-left: 0px; font-style: normal; font-weight: 600; letter-spacing: 0.96px; --paragraph-dot-color: #005de5; text-align: left;\">\u00c9tudes de cas<\/p>\n<h2 class=\"heading-two wp-block-heading has-text-4-xl-font-size\">Approuv\u00e9 par des clients du monde entier<\/h2>\n<p>\u00a0<\/p>\n<p>Nos clients nous disent que nous agissons comme un prolongement de leur \u00e9quipe et que nous leur apportons une expertise de haut niveau \u00e0 chaque \u00e9tape du processus de d\u00e9couverte de m\u00e9dicaments. Que nous vous accompagnions tout au long du processus ou seulement sur une partie, notre objectif n\u2019est pas simplement de vous faire passer \u00e0 l\u2019\u00e9tape suivante, mais de jeter les bases d\u2019un m\u00e9dicament commercialis\u00e9 avec succ\u00e8s. <\/p>\n\n                    <\/div>\n                                    <\/div>\n            <\/div>\n            \n        <div x-ref=\"sliderContainer\" class=\"Carousel__Container h-full \">\n        <div class=\"Carousel__Wrapper overflow-hidden  Carousel--snap-scroll Carousel--snap-left \" style=\"padding-top:0;padding-bottom:var(--wp--preset--spacing--60);;\">\n            <div class=\"Carousel\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-2d9db6af00b70626cb39c8cbd19ab2f6\" style=\"font-style:normal;font-weight:500\">De la prise de contact \u00e0 la pr\u00e9-nomination des candidats en 18 mois  <\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-e0aab337ded968a4ea9a439c552f5afa\">En passant de la phase de s\u00e9lection \u00e0 la nomination de pr\u00e9-candidat en moins de la moiti\u00e9 du d\u00e9lai standard du secteur, ce programme d\u00e9montre comment des \u00e9quipes scientifiques connect\u00e9es et des informations en temps r\u00e9el peuvent acc\u00e9l\u00e9rer les d\u00e9couvertes complexes.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--5\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/storm-therapeutics-from-lead-to-pre-candidate-nomination-in-18-months\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.webp 600w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-469x360.webp 469w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"600\" height=\"461\" class=\"absolute inset-0 w-full h-full object-cover\" alt=\"STORM Therapeutics logo featuring a stylized DNA helix and gradient background\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNjAwIiBoZWlnaHQ9IjQ2MSIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature.webp 600w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/storm-therapeutics-logo-feature-469x360.webp 469w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-b3d2fcb4c215eda5e0b576b58fb7dce5\" style=\"font-style:normal;font-weight:500\">Sitryx : Donner vie aux nouvelles id\u00e9es<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-47653e2d0a82108f47008efbf0d1df7d\">De nombreux programmes de recherche de m\u00e9dicaments prometteurs voient le jour au sein de jeunes entreprises de biotechnologie. Pourtant, \u00e0 leurs d\u00e9buts, ces nouvelles organisations disposent rarement des ressources ou des infrastructures de laboratoire n\u00e9cessaires pour transformer imm\u00e9diatement leurs id\u00e9es novatrices en un nouveau m\u00e9dicament. <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--6\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/sitryx-empowering-new-ideas-2\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Frame-1597884672-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-8f5dae3bf4ede09e581e582784ac22e9\" style=\"font-style:normal;font-weight:500\">Cr\u00e9ation rapide d\u2019id\u00e9es gr\u00e2ce \u00e0 l\u2019IA g\u00e9n\u00e9rative (GenAI) avec Iktos Makya<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-7cd6cbe0d998822428c1c1ddbbf96bdb\">Les principaux algorithmes <a href=\"\/drug-discovery\/computer-aided-drug-design\/artificial-intelligence-ai\/\"><strong>d\u2019intelligence artificielle<\/strong><\/a> g\u00e9n\u00e9rative (GenAI) pour la conception <em>de novo<\/em> sont utilis\u00e9s de mani\u00e8re routini\u00e8re dans nos programmes de chimie m\u00e9dicinale pour permettre une g\u00e9n\u00e9ration rapide d\u2019id\u00e9es afin d\u2019atteindre les objectifs du projet.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--7\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/rapid-creation-of-ideas-using-generative-ai-genai-with-iktos-makya\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/AI_case_study_banner_final_mock_up-scaled-e1762789851208-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-d0460f53a4ac9daf7767812b0402b7d9\" style=\"font-style:normal;font-weight:500\">Corcept Therapeutics : Collaboration int\u00e9gr\u00e9e en mati\u00e8re de d\u00e9couverte de m\u00e9dicaments<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-0507f9fe29a19aef2cfafcb9851d28eb\">Corcept Therapeutics, situ\u00e9e \u00e0 Menlo Park, en Californie, est un chef de file dans la d\u00e9couverte et le d\u00e9veloppement de m\u00e9dicaments qui r\u00e9gulent les effets du cortisol.  <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--8\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/corcept-therapeutics-integrated-drug-discovery-collaboration\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/Posters-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-b2e7fb3b48d59c1c0a1e4af5911cd8f0\" style=\"font-style:normal;font-weight:500\">Campagne d\u2019optimisation des leads CellCentric \u2013 CCS1477<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-3bba5e28bf9359510668296271677c81\">CellCentric d\u00e9veloppe de nouveaux traitements contre le cancer en s\u2019appuyant sur sa compr\u00e9hension de l\u2019\u00e9pig\u00e9n\u00e9tique.  <\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--9\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/cellcentric-lead-optimisation-campaign\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1293-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-e907cedde045f1eeeb26ed9340006da1\" style=\"font-style:normal;font-weight:500\">D\u00e9couverte de cibles \u00e9pig\u00e9n\u00e9tiques par criblage de fragments, ciblant BRD3.<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-27cee9809d96fc20c4fa6dfddd921d44\">La d\u00e9couverte de m\u00e9dicaments bas\u00e9e sur des fragments permet d\u2019explorer un large \u00e9ventail de l\u2019espace chimique gr\u00e2ce \u00e0 une biblioth\u00e8que relativement restreinte mais diversifi\u00e9e de petites mol\u00e9cules.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--10\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/fragment-based-hit-discovery-for-the-epigenetic-target-brd3\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/TechnicalNotes-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-72e8cf26 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group h-full has-border-color has-gray-200-border-color has-background overflow-hidden has-global-padding is-layout-constrained wp-container-core-group-is-layout-639b5052 wp-block-group-is-layout-constrained\" style=\"border-width:1px;border-radius:1.5rem;background-color:#f9f2e8;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\">\n<div class=\"wp-block-columns h-full is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group h-full is-vertical is-content-justification-left is-nowrap is-layout-flex wp-container-core-group-is-layout-5c292df3 wp-block-group-is-layout-flex\" style=\"padding-top:var(--wp--preset--spacing--45);padding-right:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--45);padding-left:var(--wp--preset--spacing--45)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-relative md:relative md:h-relative relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 90%; --height-md-relative: 90%;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-grey-blue-1000-color has-text-color has-link-color has-text-lg-font-size wp-elements-c331df6226ab72dc1083938b26c7a581\" style=\"font-style:normal;font-weight:500\">Identification de 3 compos\u00e9s actifs en phase clinique et de 6 candidats au d\u00e9veloppement<\/h3>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-2a49c5ce524b34a8c2c8f1a72b4f5bc9\">Soci\u00e9t\u00e9 britannique de d\u00e9couverte de m\u00e9dicaments \u00e0 petites mol\u00e9cules<\/p>\n\n\n\n<p class=\"has-placeholder-grey-color has-text-color has-link-color has-text-lg-font-size wp-elements-859e1996edaa09783335ee8ebafcdae9\">Il convient de se concentrer sur l\u2019identification de nouveaux traitements pour les maladies respiratoires inflammatoires, telles que la BPCO.<\/p>\n\n\n\n<div style=\"height:1.5vw\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-fit md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--11\" modaltype=\"\"><a class=\"wp-block-button__link has-ivory-000-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/case-study\/hit-identification-to-3-compounds-in-the-clinic-and-6-development-candidates\/\" style=\"background-color:#005de5\">Lisez l\u2019\u00e9tude de cas<\/a><\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center h-full is-layout-flow wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-bottom:0;flex-basis:50%\"><section class=\"Pegasus__Container w-full   lg:relative lg:h-fixed md:relative md:h-relative has-full-height-md relative h-fixed overflow-hidden text-content-dark mobile-stacking-standard   h-full is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-fixed: 460px; --height-md-relative: 100%; --height-fixed: 320px;   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media object-cover absolute inset-0 w-full h-full\" style=\"aspect-ratio:1;\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"598\" height=\"460\" class=\"absolute inset-0 w-full h-full object-cover\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTk4IiBoZWlnaHQ9IjQ2MCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-300x231.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1.webp 598w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/11\/PRP1262-scaled-1-468x360.webp 468w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n        <\/div>\n    <\/div>\n    \n\t\t\t\t\n\t\t\t\t\n                <\/div>\n    <\/section>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-e84fdc4b wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-2c75125d wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-6b39e634dbe4095c593657fa07ae719f\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-2e10595cf5982a11aec7b19cef561f98 wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Actualit\u00e9s et ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data='postGrid({\"respondToFiltering\":true,\"singleFilterMode\":true,\"initialFilterSlug\":\"post\"})' class=\"Post__Grid relative\" style=\"--post-grid-grid-cols: 3; --post-grid-row-gap: 1.5rem;\" data-single-filter-mode=\"true\" data-show-all-button=\"false\" data-initial-filter=\"post\">\n                                <div class=\"Post__Grid-filters-wrapper relative flex flex-col-reverse overflow-auto filter-between pt-4 pb-8 has-body-font-family gap-8 sm:gap-4 md:gap-0\">\n\t<div class=\"Post__Grid-filters relative inline-flex \">\n\t\t<div class=\"p-1 flex space-x-1 rounded-full items-center overflow-auto no-scrollbar bg-ivory-300\">\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" isloading='true;\"' class=\"w-auto px-6 h-9 font-normal font-body leading-none rounded-full whitespace-nowrap transition-colors ease-in-out\" :class=\"filterIsActive('post', 'post_type', 'post_type') ? 'bg-white text-black pointer-events-none' : 'bg-transparent text-black'\">\n\t\t\t\t\t\t<span>Nouvelles<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t\t\t\t\t<button type=\"button\" isloading='true;\"' class=\"w-auto px-6 h-9 font-normal font-body leading-none rounded-full whitespace-nowrap transition-colors ease-in-out\" :class=\"filterIsActive('blog,webinar-and-podcast,technical-note,protocol,journal-paper,e-book,poster,case-study', 'post_type', 'post_type') ? 'bg-white text-black pointer-events-none' : 'bg-transparent text-black'\">\n\t\t\t\t\t\t<span>Ressources<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\n                \n\n        \n        \n            <div class=\"Post__Grid-grid   flex-col relative\" data-pegasus-filterable=\"block_789a0562bc772eeb9b7507d8a7b00188\">\n                <div x-cloak x-show=\"isLoading\" class=\"absolute -top-3 -left-3 -right-3 -bottom-3 flex items-start justify-center pt-8 md:items-center md:pt-0 z-10 rounded-2xl overflow-visible transition duration-200 pointer-events-none bg-white\/80 backdrop-blur-sm\" style=\"background-color: rgb(255 255 255 \/ 80%);\">\n                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"50\" height=\"50\" viewbox=\"0 0 40 48\" role=\"img\" aria-label=\"Loading\" style=\"color:#005DE5\">\n                        <title>Loading\u2026<\/title>\n                        <g id=\"spinner\" fill=\"currentColor\">\n                            <path d=\"M19.6241 6.30823C21.3654 6.30823 22.7735 4.89753 22.7735 3.15412C22.7735 1.4107 21.3654 0 19.6241 0C17.8828 0 16.4746 1.4107 16.4746 3.15412C16.4746 4.89753 17.8872 6.30823 19.6241 6.30823Z\"><\/path>\n                            <path d=\"M19.629 47.5563C21.3703 47.5563 22.7784 46.1456 22.7784 44.4022C22.7784 42.6587 21.3703 41.248 19.629 41.248C17.8876 41.248 16.4795 42.6587 16.4795 44.4022C16.4795 46.1456 17.8876 47.5563 19.629 47.5563Z\"><\/path>\n                            <path d=\"M36.1016 14.5602C37.8385 14.5602 39.2511 13.1495 39.2511 11.4061C39.2511 9.66266 37.8385 8.25195 36.1016 8.25195C34.3647 8.25195 32.9521 9.66266 32.9521 11.4061C32.9521 13.1495 34.3603 14.5602 36.1016 14.5602Z\"><\/path>\n                            <path d=\"M3.14946 39.3043C4.88633 39.3043 6.29894 37.8936 6.29894 36.1502C6.29894 34.4068 4.88633 32.9961 3.14946 32.9961C1.41259 32.9961 0 34.4068 0 36.1502C0 37.8936 1.41259 39.3043 3.14946 39.3043Z\"><\/path>\n                            <path d=\"M19.6318 8.25195C20.3868 8.25197 21.1374 8.3047 21.8701 8.41113H21.8682C29.3743 9.49892 35.1348 15.967 35.1348 23.7783C35.1346 31.5902 29.3687 38.0576 21.8662 39.1445C21.7983 39.1346 21.7308 39.1211 21.6631 39.1104C21.7321 39.1213 21.8008 39.1354 21.8701 39.1455C21.1418 39.2519 20.3957 39.3047 19.6318 39.3047C11.0674 39.3047 4.12402 32.3534 4.12402 23.7783C4.12405 15.2032 11.0674 8.25195 19.6318 8.25195ZM19.623 12.6162C14.5414 12.6162 10.254 16.0262 8.91406 20.6855C8.91072 20.7021 8.90661 20.7188 8.90332 20.7354C8.62796 21.7023 8.48145 22.7182 8.48145 23.7783C8.48145 24.8386 8.63235 25.8591 8.90332 26.8262C8.9061 26.8402 8.90929 26.8541 8.91211 26.8682C10.2498 31.5309 14.539 34.9395 19.623 34.9395C25.7751 34.9393 30.7674 29.9399 30.7676 23.7783C30.7676 17.6166 25.7797 12.6164 19.623 12.6162Z\"><\/path>\n                            <animatetransform attributename=\"transform\" type=\"rotate\" from=\"0 19.6318 23.7783\" to=\"360 19.6318 23.7783\" dur=\"1s\" repeatcount=\"indefinite\"><\/animatetransform>\n                        <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributename=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatcount=\"indefinite\"><\/animate>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-craving-and-relapse\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Craving and Relapse in Addiction: Preclinical Models That Drive Discovery<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-craving-and-relapse\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Craving and Relapse in Addiction: Preclinical Models That Drive Discovery<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFocusing on the craving phase of addiction, this article examines how behavioral pharmacology models capture cue\u2011driven drug seeking and relapse vulnerability.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-substance-use-withdrawal\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Substance Use Withdrawal: How Preclinical Models Inform Treatment Development<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/preclinical-models-of-substance-use-withdrawal\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Substance Use Withdrawal: How Preclinical Models Inform Treatment Development<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFocusing on the withdrawal phase of addiction, this article examines how behavioral pharmacology models assess drug dependence and therapeutic intervention in preclinical studies.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/substance-use-intoxication-binge-insights-from-preclinical-models\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Substance Use Intoxication (Binge): Insights from Preclinical Models<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/substance-use-intoxication-binge-insights-from-preclinical-models\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Substance Use Intoxication (Binge): Insights from Preclinical Models<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tFocusing on the intoxication phase of addiction, this article examines how behavioral pharmacology models capture reward, reinforcement and binge\u2011like drug use in preclinical studies.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/drug-addiction-a-public-health-issue\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Drug Addiction: A Public Health Issue that Refuses to Go Away<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Blog\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTYwMCIgaGVpZ2h0PSI5NDciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/blog-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/blog\/drug-addiction-a-public-health-issue\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Drug Addiction: A Public Health Issue that Refuses to Go Away<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tDrug addiction remains one of the most persistent and complex public health challenges worldwide. Despite advances in prevention and treatment, drug\u2011related harm and mortality continue to rise, underscoring the need for deeper biological understanding and more predictive models to support the development of new therapies.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tBlog\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/journal-paper\/multidisciplinary-review-method-for-novel-target-identification-and-prioritization-for-neurodegenerative-diseases\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Multidisciplinary review method for novel target identification and prioritization for neurodegenerative diseases<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Joournal\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/journal-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/journal-paper\/multidisciplinary-review-method-for-novel-target-identification-and-prioritization-for-neurodegenerative-diseases\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Multidisciplinary review method for novel target identification and prioritization for neurodegenerative diseases<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tTatiana Rosado\u00a0Rosenstock,\u00a0Hiromitsu\u00a0Ohzeki,\u00a0Shohei\u00a0Kumagai,\u00a0Natsuno\u00a0Suda,\u00a0Colin Sambrook\u00a0Smith Abstract Target identification (Target ID) is a foundational, multi-disciplinary method for identifying\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tJournal Papers\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/introducing-our-sygnature-fsec-method\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Introducing our Sygnature-FSEC Method<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"608\" height=\"360\" class=\"w-full object-cover absolute-center !h-full\" alt=\"Sygnature Drug Discovery - Case Study\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMjQzMiIgaGVpZ2h0PSIxNDQwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-300x178.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/02\/case-study-thumbnail-1-608x360.webp 608w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/introducing-our-sygnature-fsec-method\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Introducing our Sygnature-FSEC Method<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tOne SEC run, Two fluorescence readouts, highlighting the \u201cSygnature\u201d peaks with your target protein. Here\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":6984,"parent":4342,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-4344","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>D\u00e9couverte de m\u00e9dicaments en oncologie et immuno-oncologie<\/title>\n<meta name=\"description\" content=\"Sygnature Discovery intervient dans l&#039;ensemble du processus de d\u00e9couverte de m\u00e9dicaments en oncologie, de l&#039;identification de la cible et du candidat principal \u00e0 la s\u00e9lection du candidat et au positionnement clinique.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/\" \/>\n<meta property=\"og:locale\" content=\"fr_CA\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"D\u00e9couverte de m\u00e9dicaments en oncologie et immuno-oncologie\" \/>\n<meta property=\"og:description\" content=\"Sygnature Discovery intervient dans l&#039;ensemble du processus de d\u00e9couverte de m\u00e9dicaments en oncologie, de l&#039;identification de la cible et du candidat principal \u00e0 la s\u00e9lection du candidat et au positionnement clinique.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sygnaturediscovery.com\/fr\/domaines-therapeutiques\/oncologie\/\" \/>\n<meta property=\"og:site_name\" content=\"Sygnature\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-13T09:11:03+00:00\" \/>\n<meta property=\"og:image\" 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