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'bg-blue-50 text-blue-700 font-medium' : ''\" x-on:click=\"mobileSubMenuOpen = false\">\n                                        DMPK Consultancy\n                                    <\/a>\n                                <\/li>\n                                                    <\/ul>\n\n                                                    <div class=\"mt-10 pb-5 \">\n                                \n        <div class=\"wp-block-button SubNav__ctaButton wp-block-button btn-primary dark mb-4 sm:mb-0 rounded-full inline-flex\">\n            <a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/contact\/\">Entrer en contact<\/a>\n        <\/div>\n        \n                            <\/div>\n                                            <\/div>\n                <\/div>\n            <\/div>\n            <\/div>\n<\/div>\n\n<section class=\"Pegasus__Container w-full   lg:relative lg:h-relative has-full-height-lg md:relative md:h-relative has-full-height-md relative h-fit  text-content-dark mobile-stacking-standard   banner-video -content-left -buttons is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\" --height-lg-relative: 100%; --height-md-relative: 100%;  padding-top:var(--wp--preset--spacing--60);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full \" style=\"background-color:#f9f2e8;\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-center  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-b98cb522 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-vertically-aligned-bottom is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-176c6c22 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-content-tertiary-color has-text-color has-link-color has-tag-style wp-elements-675e76b1efbdd13e9ac9ff7888e300bc wp-block-paragraph\" style=\"padding-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:600;--paragraph-dot-color:#005de5\">Solutions scientifiques | DMPK<\/p>\n\n\n\n<h1 class=\"wp-block-heading has-content-primary-color has-text-color has-link-color has-text-4-xl-font-size wp-elements-c613a079ba6b0a7bf85d954f1f1a6818\" style=\"margin-bottom:var(--wp--preset--spacing--30);font-style:normal;font-weight:400\">Biotransformation<\/h1>\n\n\n\n<p class=\"has-content-secondary-color has-text-color has-link-color has-text-base-font-size wp-elements-a397556e1aa40e8c4c37c028370c1ec1 wp-block-paragraph\" style=\"margin-bottom:var(--wp--preset--spacing--45);line-height:1.4\">Sygnature Discovery propose des solutions de biotransformation avanc\u00e9es qui vous aident \u00e0 optimiser vos compos\u00e9s et \u00e0 prendre des d\u00e9cisions \u00e9clair\u00e9es plus rapidement. Nos scientifiques associent une expertise pointue \u00e0 des plateformes analytiques de pointe pour fournir des donn\u00e9es haute r\u00e9solution, gage de succ\u00e8s, de l\u2019identification des compos\u00e9s actifs \u00e0 la s\u00e9lection des candidats pr\u00e9cliniques. <\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-2e73da63 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-fill is-style-fill--1\" modaltype=\"side-inset\" data-pegasus-modal=\"Modal--side-inset\"><a class=\"wp-block-button__link has-white-color has-aqua-background-color has-text-color has-background has-link-color wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/formulaire-de-discussion-de-projet-modal\/\" style=\"padding-right:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">Entrer en contact<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:50%\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-28462c10 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Environnement de laboratoire dot\u00e9 d'instruments analytiques avanc\u00e9s repr\u00e9sentant les \u00e9tudes de m\u00e9tabolisme et de pharmacocin\u00e9tique des m\u00e9dicaments (DMPK) pour une conception rationnelle et une prise de d\u00e9cision.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-scaled.webp\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/drug-metabolism-pharmacokinetics-dmpk-laboratory-analysis-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--90); \" id=\"how-it-works\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-ivory-300-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8904fc3d wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:23.8%\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-2 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-b5580a65 wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"is-style-tag has-text-color has-link-color has-tag-style wp-elements-aa44ba95d7be2dff44c637536503b178 wp-block-paragraph\" style=\"color:#00102480;padding-right:0;padding-left:0;--paragraph-dot-color:#005de5\">soutenir vos recherches<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group children-fill-width is-vertical is-layout-flex wp-container-core-group-is-layout-1bbac977 wp-block-group-is-layout-flex\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-4-xl-font-size\" style=\"margin-bottom:var(--wp--preset--spacing--45)\">Comprendre la biotransformation d\u2019un compos\u00e9 est essentiel pour pr\u00e9dire son devenir m\u00e9tabolique, sa stabilit\u00e9 et ses risques potentiels.  <\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Gr\u00e2ce \u00e0 la LC-MS\/MS haute r\u00e9solution, nous obtenons un profilage m\u00e9tabolique d\u00e9taill\u00e9 permettant d\u2019identifier les voies m\u00e9taboliques primaires et secondaires, les interm\u00e9diaires r\u00e9actionnels et les diff\u00e9rences intersp\u00e9cifiques. Ces informations contribuent \u00e0 l\u2019optimisation de la structure, \u00e9tayent les \u00e9valuations de s\u00e9curit\u00e9 et orientent les d\u00e9cisions strat\u00e9giques tout au long du processus de d\u00e9couverte de m\u00e9dicaments. <\/p>\n\n\n\n<div style=\"margin-top:var(--wp--preset--spacing--60)\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<section x-data=\"PegasusMediaBlock\" class=\"Media full-width has-aspect-ratio aspect-59x35 has-overlay w-full\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-1024x682.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Environnement de laboratoire dot\u00e9 d'\u00e9quipements analytiques de pointe utilis\u00e9s pour les \u00e9tudes de biotransformation et le profilage des m\u00e9tabolites via les techniques LC\/MS\/MS.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-1024x682.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-1536x1024.webp 1536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-metabolite-analysis-lc-ms-ms-laboratory-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-light mobile-stacking-standard   stacking-content -sticky-heading -two-columns is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--100); \" id=\"sticky-scroll-progress\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t<div class=\"row-background absolute w-full bottom-0 left-0 z-0 h-full has-dark-blue-700-background-color\" style=\"\">\n<\/div>\n\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-b4425dac wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column has-global-padding is-layout-constrained wp-block-column-is-layout-constrained\">\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"margin-top:var(--wp--preset--spacing--80);margin-bottom:var(--wp--preset--spacing--80);padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Progress Progress--left Progress--scroll absolute z-[1000]\" style=\"--progress-thickness: 1px; --progress-color: var(--wp--preset--color--ivory-300); --progress-background: rgba(249, 242, 232, 0.2);\" x-data=\"progress()\" x-init='init({\"position\":\"left\",\"eventType\":\"scroll\",\"scrollOptions\":{\"scroll_target\":\"m\\u00e8re\",\"container_selector\":\"\"},\"tickerOptions\":[],\"formOptions\":[],\"anchorPoints\":{\"align_points\":true,\"points\":[{\"element_id\":\"\\u00e9l\\u00e9ment-collant-1\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-2\",\"label\":\"\"},{\"element_id\":\"\\u00e9l\\u00e9ment-collant-3\",\"label\":\"\"}]},\"showEndDot\":true,\"containerScrollOffset\":0.2,\"progressThreshold\":0.005})' x-cloak data-position=\"left\" data-event-type=\"scroll\">\n    <div class=\"Progress__track bg-[var(--progress-background,rgba(0,124,186,0.2))] relative overflow-visible\" x-ref=\"track\">\n        <div class=\"Progress__fill transition-all duration-100 ease-out bg-[var(--progress-color,#0053CC)]\" x-ref=\"fill\"><\/div>\n            <\/div>\n<\/div>\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-cfb3f328 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-5d756761 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Biotransformation \u2013 \u00c9lucidation structurale<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">L\u2019identification des m\u00e9tabolites et l\u2019\u00e9lucidation de leur structure sont essentielles \u00e0 la caract\u00e9risation des voies de biotransformation et des profils d\u2019impuret\u00e9s. Nous utilisons des syst\u00e8mes <em>in vitro<\/em> , tels que des h\u00e9patocytes primaires cryoconserv\u00e9s et des microsomes h\u00e9patiques, pour simuler le m\u00e9tabolisme humain et identifier et caract\u00e9riser les m\u00e9tabolites des m\u00e9dicaments. Ces profils sont ensuite compar\u00e9s entre diff\u00e9rentes esp\u00e8ces pr\u00e9cliniques afin d\u2019\u00e9valuer la transposabilit\u00e9 m\u00e9tabolique et d\u2019orienter le choix des esp\u00e8ces pour les \u00e9tudes toxicologiques.  <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-5d756761 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Notre approche<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Notre approche combine la spectrom\u00e9trie de masse \u00e0 haute r\u00e9solution et \u00e0 haute pr\u00e9cision (HRMS) avec la d\u00e9tection par barrette de photodiodes (PDA) pour une d\u00e9tection sensible et s\u00e9lective des m\u00e9tabolites majeurs et mineurs. En int\u00e9grant des analyses cibl\u00e9es \u00e0 des strat\u00e9gies d\u2019acquisition de donn\u00e9es ind\u00e9pendantes (DIA), nous identifions les m\u00e9tabolites potentiels, \u00e9lucidons les produits de d\u00e9gradation et les impuret\u00e9s, et garantissons une d\u00e9termination pr\u00e9cise de la masse et de la composition \u00e9l\u00e9mentaire. Ce profilage complet \u00e9claire les analyses de chimie m\u00e9dicinale, soutient les \u00e9valuations de s\u00e9curit\u00e9 et renforce les dossiers r\u00e9glementaires.  <\/p>\n<\/div>\n\n\n\n<div id=\"sticky-item-1\" class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-5d756761 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--site-gutter);padding-bottom:var(--wp--preset--spacing--80)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\" style=\"font-style:normal;font-weight:300\">Pourquoi choisir Sygnature Discovery pour votre accompagnement en biotransformation ?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Notre \u00e9quipe MetID r\u00e9alise des \u00e9tudes sur mesure utilisant la spectrom\u00e9trie de masse \u00e0 haute r\u00e9solution pour une d\u00e9tection pr\u00e9cise et une \u00e9lucidation structurale. Nous analysons une large gamme de matrices, incluant des syst\u00e8mes <em>in vitro<\/em> (h\u00e9patocytes primaires cryoconserv\u00e9s, microsomes h\u00e9patiques, plasma, sang total) et des \u00e9chantillons <em>in vivo<\/em> issus d\u2019\u00e9tudes humaines et animales \u2013 urine, selles, plasma, bile et sang. Cette approche personnalis\u00e9e garantit des r\u00e9sultats scientifiquement rigoureux, en parfaite ad\u00e9quation avec les objectifs de votre projet.  <\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><section class=\"Pegasus__Container w-full hidden sm:block  sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-3 is-position-sticky\" style=\"  padding-top:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\"><div class=\"Reveal \" x-data='reveal({\"initiallyVisible\":true,\"element\":\"autre\",\"elementId\":\"\\u00e9l\\u00e9ment-collant-1\",\"action\":\"vue\"})' styles=\";\">\n\t        \n    \t\t<div x-show=\"show\" x-transition:enter=\"transition ease-out duration-500\" x-transition:enter-start=\"opacity-0\" x-transition:enter-end=\"opacity-100\" x-transition:leave=\"transition ease-in duration-500 absolute inset-0\" x-transition:leave-start=\"opacity-100\" x-transition:leave-end=\"opacity-0\" x-cloak>\n\n\t\t\t<div class=\"acf-innerblocks-container\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-640x427.webp 640w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1336\" height=\"891\" class=\"image-original \" alt=\"Laboratory setup featuring advanced analytical instrumentation used for biotransformation studies and structural elucidation, supporting metabolite identification and impurity profiling in drug development.\" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-768x512.webp 768w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-1024x683.webp 1024w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry.webp 1336w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-540x360.webp 540w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/biotransformation-structural-elucidation-mass-spectrometry-640x427.webp 640w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\t\n\t\t<\/div>\n    \n\t\t\t<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full block sm:hidden md:hidden  sticky top-0 lg:relative lg:h-fixed md:relative md:h-fit relative  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-4 is-position-sticky\" style=\" --height-lg-fixed: 630px;  padding-top:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--80); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n<section x-data=\"PegasusMediaBlock\" class=\"Media original has-aspect-ratio aspect-1x1 shrink-0\" style=\"\">\n            \n                                    <picture><source srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" width=\"561\" height=\"588\" class=\"image-original \" loading=\"eager\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.jpg\" srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-286x300.webp 286w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1.webp 561w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/10\/Scientist-Administering-607x589-1-343x360.webp 343w\"><\/source><\/picture>\n\n                \n            <\/section>\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--100);padding-bottom:var(--wp--preset--spacing--60); \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group is-content-justification-space-between is-nowrap is-layout-flex wp-container-core-group-is-layout-178593e6 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-7703b6f3 wp-block-group-is-layout-constrained\" style=\"margin-bottom:var(--wp--preset--spacing--20)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<p class=\"has-text-align-left is-style-tag has-text-color has-link-color has-text-xs-font-size has-tag-style wp-elements-db8ae020b0d7ab6b85a31c1d595ff20f wp-block-paragraph\" style=\"color:#001024b3;padding-right:0;padding-left:0;font-style:normal;font-weight:600;letter-spacing:0.96px;--paragraph-dot-color:#005de5\">Centre de ressources<\/p>\n\n\n\n<h2 class=\"wp-block-heading has-text-align-left has-text-color has-link-color has-text-4-xl-font-size wp-elements-f4f353d6f3d0ad312919a94ff2812b8b wp-container-content-d25f37ba\" style=\"color:#002b46;margin-top:0;margin-bottom:var(--wp--preset--spacing--30)\">Ressources connexes<\/h2>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n\n\n\n\n<section x-data='postGrid({\"respondToFiltering\":true,\"singleFilterMode\":true,\"initialFilterSlug\":\"post\"})' class=\"Post__Grid relative\" style=\"--post-grid-grid-cols: 3; 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'bg-white text-black pointer-events-none' : 'bg-transparent text-black'\">\n\t\t\t\t\t\t<span>Ressources<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\n                \n\n        \n        \n            <div class=\"Post__Grid-grid   flex-col relative\" data-pegasus-filterable=\"block_bbfa08deb0154ad9b65296f43393b189\">\n                <div x-cloak x-show=\"isLoading\" class=\"absolute -top-3 -left-3 -right-3 -bottom-3 flex items-start justify-center pt-8 md:items-center md:pt-0 z-10 rounded-2xl overflow-visible transition duration-200 pointer-events-none bg-white\/80 backdrop-blur-sm\" style=\"background-color: rgb(255 255 255 \/ 80%);\">\n                    <svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"50\" height=\"50\" viewbox=\"0 0 40 48\" role=\"img\" aria-label=\"Loading\" style=\"color:#005DE5\">\n                        <title>Loading\u2026<\/title>\n                        <g id=\"spinner\" fill=\"currentColor\">\n                         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<path d=\"M19.6318 8.25195C20.3868 8.25197 21.1374 8.3047 21.8701 8.41113H21.8682C29.3743 9.49892 35.1348 15.967 35.1348 23.7783C35.1346 31.5902 29.3687 38.0576 21.8662 39.1445C21.7983 39.1346 21.7308 39.1211 21.6631 39.1104C21.7321 39.1213 21.8008 39.1354 21.8701 39.1455C21.1418 39.2519 20.3957 39.3047 19.6318 39.3047C11.0674 39.3047 4.12402 32.3534 4.12402 23.7783C4.12405 15.2032 11.0674 8.25195 19.6318 8.25195ZM19.623 12.6162C14.5414 12.6162 10.254 16.0262 8.91406 20.6855C8.91072 20.7021 8.90661 20.7188 8.90332 20.7354C8.62796 21.7023 8.48145 22.7182 8.48145 23.7783C8.48145 24.8386 8.63235 25.8591 8.90332 26.8262C8.9061 26.8402 8.90929 26.8541 8.91211 26.8682C10.2498 31.5309 14.539 34.9395 19.623 34.9395C25.7751 34.9393 30.7674 29.9399 30.7676 23.7783C30.7676 17.6166 25.7797 12.6164 19.623 12.6162Z\"><\/path>\n                            <animatetransform attributename=\"transform\" type=\"rotate\" from=\"0 19.6318 23.7783\" to=\"360 19.6318 23.7783\" dur=\"1s\" repeatcount=\"indefinite\"><\/animatetransform>\n                        <\/g>\n                        <g fill=\"currentColor\" opacity=\"1\">\n                            <path>\n                                <animate attributename=\"opacity\" values=\"1;0.4;1\" dur=\"1.2s\" begin=\"0s\" repeatcount=\"indefinite\"><\/animate>\n                            <\/path>\n                        <\/g>\n                    <\/svg>\n                <\/div>\n\n                                                \n                                                                                        <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/polq-inhibitor-ai-drug-discovery-oncology\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Combining Artificial Intelligence and Human Expertise in Pursuit of Novel PolQ Inhibitors<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/04\/Combining-artificial-intelligence-and-human-expertise-in-pursuit-of-novel-PolQ-inhibitors-pdf-212x300.jpg 212w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"application\/pdf\"><img decoding=\"async\" loading=\"lazy\" width=\"255\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNDIzOCIgaGVpZ2h0PSI1OTkyIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/04\/Combining-artificial-intelligence-and-human-expertise-in-pursuit-of-novel-PolQ-inhibitors.pdf\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/04\/Combining-artificial-intelligence-and-human-expertise-in-pursuit-of-novel-PolQ-inhibitors-pdf-212x300.jpg 212w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/polq-inhibitor-ai-drug-discovery-oncology\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Combining Artificial Intelligence and Human Expertise in Pursuit of Novel PolQ Inhibitors<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tSygnature Discovery, in collaboration with Iktos, presents a poster outlining the\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tPosters\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/photocatalyzed-ring-opening-of-bicyclobutane\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Photocatalyzed Ring-Opening of Bicyclobutane<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/photocatalyzed-bcp-ring-opening-212x300.webp 212w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/photocatalyzed-bcp-ring-opening-255x360.webp 255w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"255\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"Scientific poster visual illustrating photocatalytic synthesis of bicyclo[1.1.1]pentanes from bicyclobutane and diazo compounds\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTgxMSIgaGVpZ2h0PSIyNTYwIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjxyZWN0IHdpZHRoPSIxMDAlIiBoZWlnaHQ9IjEwMCUiIGZpbGw9IiNmM2Y0ZjYiLz48L3N2Zz4=\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/photocatalyzed-bcp-ring-opening-scaled.webp\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/photocatalyzed-bcp-ring-opening-212x300.webp 212w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/photocatalyzed-bcp-ring-opening-255x360.webp 255w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/photocatalyzed-ring-opening-of-bicyclobutane\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Photocatalyzed Ring-Opening of Bicyclobutane<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tAccess to 1,2,3-Trisubstituted Bicyclo[1.1.1]pentanes Bicyclo[1.1.1]pentanes (BCPs) have emerged as valuable bioisosteres for aromatic rings\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tPosters\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/how-the-structure-of-g6b-b-was-determined\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">How the Structure of G6b-B was Determined<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X-300x164.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.webp 528w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"528\" height=\"288\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTI4IiBoZWlnaHQ9IjI4OCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X-300x164.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/6R0X.webp 528w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/how-the-structure-of-g6b-b-was-determined\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">How the Structure of G6b-B was Determined<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tOur journey started, as it often does, with an X-ray crystallography project which looked\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/molecular-glue-optimization-using-ai-and-computational-modeling\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Accelerating Molecular Glue Optimization\/Prioritization Using a Computational Workflow<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/molecular-glue-optimisation-computational-workflow-212x300.webp 212w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/molecular-glue-optimisation-computational-workflow-255x360.webp 255w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"255\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" alt=\"Scientific poster on molecular glue optimisation using generative AI and computational modelling\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNzI0IiBoZWlnaHQ9IjEwMjQiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/molecular-glue-optimisation-computational-workflow.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/molecular-glue-optimisation-computational-workflow-212x300.webp 212w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/molecular-glue-optimisation-computational-workflow-255x360.webp 255w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/poster\/molecular-glue-optimization-using-ai-and-computational-modeling\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Accelerating Molecular Glue Optimization\/Prioritization Using a Computational Workflow<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tMolecular glues are transforming targeted protein degradation but optimization remains complex and resource-intensive. This poster presents an integrated computational chemistry workflow combining generative AI and physics-based modelling to enable faster, more rational molecular glue design and prioritization.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tPosters\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/isotopic-labelling-of-proteins-in-a-eukaryotic-system\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">Isotopic Labelling of Proteins in a Eukaryotic System<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-e1781615698526.webp 536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-540x360.webp 540w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"540\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTM2IiBoZWlnaHQ9IjM1NyIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-e1781615698526.webp\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-300x200.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-e1781615698526.webp 536w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/Designer-1-540x360.webp 540w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/isotopic-labelling-of-proteins-in-a-eukaryotic-system\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">Isotopic Labelling of Proteins in a Eukaryotic System<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\t\u201cAn Effective Solution for Labelling when Protein Folding is a Challenge\u201d In this case study\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t                                                                            <div class=\"Post__Grid-post \" data-pegasus-single-card>\n\t<div class=\"group\">\n\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/x-ray-crystallography-structure-of-erap1-complexes\/\" class=\"block rounded-2xl overflow-hidden \">\n\t\t\t\t\t<span class=\"sr-only\">X-ray crystallography structure of ERAP1 complexes<\/span>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"w-full relative overflow-hidden h-0 pb-[64%]\">\n\t\t\t\t\t\t\t<picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"531\" height=\"360\" class=\"w-full object-cover group-hover:scale-105 transition-transform duration-500 ease-in-out absolute-center !h-full group-hover:-translate-y-1\/2 group-hover:-translate-x-1\/2\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMTAwMCIgaGVpZ2h0PSI2NzgiIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PHJlY3Qgd2lkdGg9IjEwMCUiIGhlaWdodD0iMTAwJSIgZmlsbD0iI2YzZjRmNiIvPjwvc3ZnPg==\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1.png\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-300x203.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/06\/ERAP1-531x360.webp 531w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\n\t\t\t\t\t<div class=\"pt-6\">\n\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/case-study\/x-ray-crystallography-structure-of-erap1-complexes\/\" class=\"font-medium has-text-2-xl-font-size has-body-font-family \">X-ray crystallography structure of ERAP1 complexes<\/a>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"mt-3 has-text-sm-font-size text-black has-body-font-family\">\n\t\t\t\t\t\t\tWe were asked by Greywolf Therapeutics to provide support for an endoplasmic reticulum aminopeptidase-1 (ERAP1)\u2026\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap items-center gap-3 mt-4 has-body-font-family\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"flex flex-wrap -mx-px gap-4\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"tag inline-block mx-px my-px py-1 text-base font-regular text-blue-500 tracking-small\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\tCase Studies\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t<\/div>\n\t\t\t<\/div>\n<\/div>\n\n                                                                \t\t\t    \n                            <\/div>\n\n        \n    \n<\/section>\n<\/div>\n\t\t\n\t        <\/section>\n\n\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--90);padding-bottom:var(--wp--preset--spacing--90); \" id=\"identification-techniques\">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-8904fc3d wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:342px\"><section class=\"Pegasus__Container w-full   sticky top-0 relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow wp-container-12 is-position-sticky\" style=\"   \">\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\">\n\n<div class=\"wp-block-group has-global-padding is-content-justification-left is-layout-constrained wp-container-core-group-is-layout-dce8ee25 wp-block-group-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h2 class=\"wp-block-heading has-text-3-xl-font-size\">Solutions connexes<\/h2>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e17f75369917380307a8227af22f62bc wp-block-paragraph\" style=\"color:#001024b3\">Nous r\u00e9unissons un m\u00e9lange dynamique de nouveaux talents et d\u2019experts chevronn\u00e9s de l\u2019industrie pharmaceutique du monde entier, garantissant l\u2019excellence \u00e0 chaque \u00e9tape de la d\u00e9couverte.<\/p>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:74.58%\">\n<div class=\"wp-block-group is-layout-grid wp-container-core-group-is-layout-832e19e4 wp-block-group-is-layout-grid\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-393eae96 wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--30)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"Form &amp; Formulation\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/Form-and-Formulation.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-1bbac977 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-62ada6e0951e3179aebea64551a38124\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/forme-et-formulation\/\">Forme et formulation<\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-ef3202aa48e1102dd72a675eb4167c94 wp-block-paragraph\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Les strat\u00e9gies int\u00e9gr\u00e9es de formulation et de forme solide r\u00e9duisent les risques, am\u00e9liorent la stabilit\u00e9 et la solubilit\u00e9 et acc\u00e9l\u00e8rent le passage de la s\u00e9lection des candidats \u00e0 la clinique.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/forme-et-formulation\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-9285342f wp-block-group-is-layout-flex\" style=\"padding-bottom:var(--wp--preset--spacing--40)\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<div class=\"wp-block-group overflow-hidden has-global-padding is-layout-constrained wp-block-group-is-layout-constrained\" style=\"border-radius:24px\" allowchildrentofillwidth=\"\" overflow=\"hidden\" flexwrap=\"\"><section x-data=\"PegasusMediaBlock\" class=\"Media full-width w-full\" style=\"\">\n            \n                                    <picture class=\"pegasus-lazy-wrapper\"><source data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/in-vivo-Pharmacology-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/in-vivo-Pharmacology.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" type=\"image\/webp\"><img decoding=\"async\" loading=\"lazy\" width=\"100%\" height=\"auto\" class=\"image-original \" alt=\"in vivo Pharmacology\" sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iNTE3IiBoZWlnaHQ9IjMyMCIgeG1sbnM9Imh0dHA6Ly93d3cudzMub3JnLzIwMDAvc3ZnIj48cmVjdCB3aWR0aD0iMTAwJSIgaGVpZ2h0PSIxMDAlIiBmaWxsPSIjZjNmNGY2Ii8+PC9zdmc+\" data-src=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/in-vivo-Pharmacology.jpg\" data-srcset=\"https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/in-vivo-Pharmacology-300x186.webp 300w, https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2026\/01\/in-vivo-Pharmacology.webp 517w\" data-sizes=\"(min-width: 1536px) 1536px, (min-width: 1280px) 1280px, (min-width: 1024px) 1024px, (min-width: 768px) 768px, (min-width: 640px) 640px, 100vw\"><\/source><\/picture>\n\n                \n            <\/section><\/div>\n\n\n\n<div class=\"wp-block-group is-vertical is-layout-flex wp-container-core-group-is-layout-1bbac977 wp-block-group-is-layout-flex\" allowchildrentofillwidth=\"\" overflow=\"\" flexwrap=\"\">\n<h3 class=\"wp-block-heading has-text-color has-link-color has-text-2-xl-font-size wp-elements-95cb6840b5cc45da381f55b6b4c9fa98\" style=\"color:#002b46;margin-bottom:var(--wp--preset--spacing--20)\"><a href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/pharmacologie-in-vivo\/\">Pharmacologie <em>in vivo<\/em><\/a><\/h3>\n\n\n\n<p class=\"has-text-color has-link-color has-text-base-font-size wp-elements-e7ea388b7a5e7a088a42b5217fefa086 wp-block-paragraph\" style=\"color:#001024b3;margin-bottom:var(--wp--preset--spacing--20)\">Les mod\u00e8les <em>in vivo<\/em> valid\u00e9s fournissent des donn\u00e9es cliniquement pertinentes dans tous les domaines th\u00e9rapeutiques, acc\u00e9l\u00e9rant la prise de d\u00e9cisions \u00e9clair\u00e9es et r\u00e9duisant les risques li\u00e9s au d\u00e9veloppement de m\u00e9dicaments.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-text-link\" modaltype=\"\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/www.sygnaturediscovery.com\/fr\/solutions-scientifiques\/pharmacologie-in-vivo\/\">Apprendre encore plus<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":7,"featured_media":13370,"parent":6627,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":true,"footnotes":""},"class_list":["post-13369","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Biotransformation<\/title>\n<meta name=\"description\" content=\"Des \u00e9tudes de biotransformation avanc\u00e9es utilisant la LC-MS\/MS pour profiler les m\u00e9tabolites, pr\u00e9dire leur devenir m\u00e9tabolique et orienter l&#039;optimisation des compos\u00e9s\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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