{"id":13327,"date":"2025-12-10T11:27:52","date_gmt":"2025-12-10T11:27:52","guid":{"rendered":"https:\/\/www.sygnaturediscovery.com\/pharmacologie-in-vivo-modulaire\/"},"modified":"2026-01-27T15:11:04","modified_gmt":"2026-01-27T15:11:04","slug":"pharmacologie-in-vivo-modulaire","status":"publish","type":"page","link":"https:\/\/www.sygnaturediscovery.com\/fr\/pharmacologie-in-vivo-modulaire\/","title":{"rendered":"Pharmacologie in vivo [Modulaire]"},"content":{"rendered":"<section class=\"Pegasus__Container w-full   relative h-fixed  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow has-background\" style=\" --height-fixed: 410px;   ;background-position:50% 50%;background-size:cover;background-image: url(&apos;https:\/\/www.sygnaturediscovery.com\/wp-content\/uploads\/2025\/12\/Frame-14920.webp&apos;);\" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  w-full\"><\/div>\n\t\t\n\t        <\/section>\n<section class=\"Pegasus__Container w-full   relative h-fit  text-content-dark mobile-stacking-standard is-layout-flow wp-block-pegasus-container-is-layout-flow\" style=\"  padding-top:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--50); \" >\n\t        \n\t\n\t\t\t\t\t\t\n\t\t        \t\t\n\t\t\t\t\t\t\t\n\t\t\t<div class=\"inner relative h-full is-flex-layout flex flex-col justify-start  container\">\n\n<h3 class=\"wp-block-heading has-text-3-xl-font-size\">Pharmacologie <em>in vivo<\/em><\/h3>\n\n\n\n<p>Notre plateforme int\u00e9gr\u00e9e <em>in vitro<\/em> , <em>ex vivo<\/em> et <em>in vivo<\/em> permet une compr\u00e9hension unifi\u00e9e de la biologie m\u00e9tabolique. Ses capacit\u00e9s incluent\u00a0: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Mod\u00e8les d&rsquo;ob\u00e9sit\u00e9 et de diab\u00e8te, y compris la n\u00e9phropathie diab\u00e9tique<\/li>\n\n\n\n<li>Mod\u00e8les MASH\/NAFLD<\/li>\n\n\n\n<li>R\u00e9duction du poids corporel, suivi de l&rsquo;apport alimentaire, analyse du m\u00e9tabolisme et de la composition corporelle<\/li>\n\n\n\n<li>Profilage des biomarqueurs hormonaux et cytokiniques<\/li>\n<\/ul>\n\n\n\n<p>Les relations PK\/PD et les signatures de biomarqueurs relient l&rsquo;engagement de la cible, la modulation des voies et l&rsquo;efficacit\u00e9 in vivo, acc\u00e9l\u00e9rant ainsi la progression vers la nomination des candidats.<\/p>\n\n<\/div>\n\t\t\n\t        <\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-13327","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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