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Synthetic and Medicinal Chemistry careers

Nottingham & Alderley Park

Sygnature Discovery is a highly respected, successful and award-winning provider of fully integrated drug discovery research programmes to the global pharmaceutical industry. Founded in 2004 with a workforce of six, we now employee over 300 scientists, mainly operating from our purpose-built facilities in BioCity, Nottingham.

Having successfully established a DMPK lab at Alderley Park at the end of 2018, Sygnature is now building upon this by opening a Chemistry department at the same site. Work is ongoing to develop the lab space and necessary equipment, but our most vital resource will be our people.

We are continuing to recruit for our Nottingham site as well as commencing recruitment at our new site in Alderley Park. We are looking for chemists across a broad range of personal experience and knowledge:

As a Project Leader you will already be an innovative and talented senior medicinal chemist with a PhD in Organic Chemistry or Medicinal Chemistry, alongside several years’ experience in a pharmaceutical company or a CRO where you have overseen and supported the work of others.

As a Senior Scientist, you are likely to have a substantial amount of drug discovery experience gained within a pharmaceutical company or a CRO, or substantial relevant post-doctoral study.

At our Scientist level, you are likely to have a PhD in Organic Chemistry or Medicinal Chemistry, or a BSc/MSc in Chemistry with additional drug discovery experience in industry.

In return you will receive an excellent training and benefits package, including a highly competitive salary which is reviewed annually, a bonus scheme, a well-regarded pension scheme, and private medical insurance. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share in our success.

We also recognise that the environment you work in is a priority, so we have built a collaborative and supportive culture with plenty of opportunities to grow and succeed, tailored to individual and business needs. This includes an excellent set of bespoke training and development courses to accelerate both your scientific and personal career growth, which will be replicated at the new site.

If you are interested in joining a successful and engaged company that places its people at the heart of its business, please apply through the link below including the following;

Apply here

1) Your CV,

2) a covering letter that briefly outlines your suitability for the role and your current notice period (if applicable), and

3) confirmation of your status of eligibility to work in the UK (we are able to consider sponsoring potential employees with relevant levels of qualifications and experience under a Tier 2 visa).

4) confirmation of which site you would like to be considered for i.e. Nottingham or Alderley Park. We are happy to consider you for both sites if you do not have a preference, but please indicate this.

Your application will be submitted through our trusted partners, LogicMelon, although only employees of Sygnature Discovery will review your application and personal data.

We will be interviewing on an ongoing basis, so please submit your application as soon as possible. We look forward to hearing from you.

If you have any questions or need further information, please contact the Careers team at Please do not submit your application to this email address.

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