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QC Officer – Nottingham or Alderley Park


Sygnature Discovery is a leading independent integrated drug discovery and non-clinical services company. Private equity-backed since 2017, the company operates fully enabled research facilities in Nottingham and Alderley Park, UK, housing nearly 400 research scientists, and has an office presence in Cambridge, MA, and South San Francisco, CA, in the USA.

Since 2011, 34 compounds discovered by Sygnature for customers have entered pre-clinical development and, so far, 17 of these have progressed to clinical trials (Phases I, II and III). In 2017, Sygnature Discovery received the prestigious Queen’s Award for Enterprise for International Trade, and in the last year has won both the Medilink Outstanding Achievement Award and the Bionow Company of the Year Award.

About the role

The DMPK team at Sygnature Discovery play an essential role in actively discovering new drugs for a broad range of projects, molecular targets and therapeutic indications.

Your tasks as a Trainee QC Officer will be varied and will involve managing multiple tasks effectively in order to meet deadlines.

Principal responsibilities will include;

  • Building and maintaining an understanding of all in vitro and in vivo assays performed by the DMPK department with a view to:
    • Understanding critical parameters to be checked
    • Understanding control compound data and acceptance
    • Understanding bioanalytical acceptance criteria
  • Performing QC checking of workbooks and reports for data accuracy and format consistency
  • Working within the Department to identify processes that lead to errors and help with directing informatics colleagues to provide solutions to these
  • Helping with the generation of reports for clients


To succeed in the role, you will have the following capabilities and experience;

  • Life Science graduate and/or equivalent quality management qualification
  • Preferably experience in a DMPK laboratory environment with experience of screening DMPK assays in a discovery environment (non-regulated)
  • Able to deliver deadlines under pressure
  • Proficient in Microsoft Office
  • Diplomatic, polite and professional
  • Contribute positively to the team
  • Organised with excellent attention to detail
  • Proficiency in document proofreading
  • Enthusiastic and self-motivated



This is a permanent position and offering an excellent training and benefits package, including a highly competitive salary which is reviewed annually, a bonus scheme, a well-regarded pension scheme, and private medical insurance. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share in our success.

We also recognise that the environment you work in is a priority, so we have built a collaborative and supportive culture with plenty of opportunities to grow and succeed, tailored to individual and business needs. This includes an excellent set of bespoke training and development courses to accelerate both your scientific and personal career growth.

If you are interested in joining a successful and engaged company that places its people at the heart of its business, please apply through the link including the following:

Apply here

1) Your CV,

2) a covering letter that briefly outlines your suitability for the role, preferred location and your current notice period (if applicable), and

3) confirmation of your status of eligibility to work in the UK (we are able to consider sponsoring potential employees with relevant levels of qualifications and experience under a Skilled Worker visa).

Your application will be submitted through our trusted partners, LogicMelon, although only employees of Sygnature Discovery will review your application and personal data.

We will be interviewing on an ongoing basis, so please submit your application as soon as possible.

If you have any questions or need further information, please contact the Careers team at Please do not submit your application to this email address.


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