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MSc/MChem Scientists – Chemistry

Build your career in Drug Discovery

Sygnature Discovery is an award-winning provider of fully-integrated drug discovery expertise to the global pharmaceutical industry. We actively engage in all stages of the drug discovery process, from hit identification through to lead optimisation and candidate nomination, as we conduct multi-disciplinary drug discovery programmes on behalf of our clients. Our core capabilities include medicinal chemistry, in vitro bioscience, in vivo pharmacology, computational sciences and informatics, and DMPK/physical sciences.

With over 200 chemists at our Nottingham site, we are home to one of the UK’s largest synthetic and medicinal chemistry groups. Our experience and enthusiasm allow us to provide our extensive international network of clients and collaborators with the cutting-edge scientific expertise and intellectual input they need to propel their drug discovery projects forward.

With demand for the many services we provide continuing to grow, we are presently looking to further expand the chemistry team at our Nottingham site via recruitment of highly motivated individuals eager to begin, or continue building, their careers in the dynamic and stimulating field of drug discovery. We are therefore keen to hear from prospective recruits who have completed a chemistry-focussed degree program to MSc level, or equivalent. Ideal candidates will have previously obtained some relevant lab experience with a focus on practical organic synthesis, either in the form of a synthetic final-year undergraduate research project, an Industrial Placement year, internship or employment since completing their university studies, or suitable combinations thereof. For more experienced candidates, positions may also be available at our Alderley Park facility.

By joining us here in the medicinal chemistry group at Sygnature, you will have the opportunity to work alongside, and learn from, our dedicated team of scientists with extensive experience in every stage of the drug discovery process. You will have continual opportunities to develop and apply creative approaches to problem solving, both within the lab and through in-house training activities. You will also be invited to attend regular seminars with industry leaders and academic collaborators to further assist in your broader scientific development. We also offer very competitive salary and benefits packages, alongside great opportunities for future personal and career growth for candidates who successfully complete a 6-month probationary period.

If you are interested in joining a successful, engaged and award-winning company that places its people at the heart of its business, please apply through the link below including the following;

Apply Here

  • CV
  • Covering letter (briefly outlining your suitability for the role) – your application will not be considered without this
  • Confirmation of your status of eligibility to work in the UK

You will submit your application through our trusted partners, LogicMelon. Please be assured that only employees of Sygnature Discovery will review your application and personal data.

We will be interviewing on a rolling basis, so would advise to submit your application as soon as possible.

If you have any questions, please contact the Careers team at

Please do not submit your application to this email address.

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