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Informatics Software Developer – Alderley Park

Sygnature Discovery are looking for a scientifically minded developer with a skillset around web technologies, relational databases and cloud services. As a member of the informatics group, you will be part of an established team, primarily supporting our DMPK activities.  This role would be particularly suited to a recent graduate from a scientific background with strong programming skills and an interest to help shape the way the team conducts software development activities.

Important is the ability to communicate and develop ideas collaboratively across different levels of the business and translate ideas into technical solutions. This also means proactively solving problems and the motivation to seek out opportunities for improvement. The candidate will liaise primarily with DMPK stakeholders, improving on, and developing new solutions according to software development best practices and adhering to company accreditation standards.

Sygnature is embarking on a phase of digital transformation at a corporate level, whilst the informatics team has recently implemented a number of Azure-based applications and microservices into production. There will be opportunities for the candidate to help shape and grow existing solutions, as well as work on fresh projects.

Main responsibilities:

  • You will undertake independent development, defining requirements with internal customers, proposing solutions and developing applications
  • You will support, update and report against database systems and existing applications
  • You will translate functional requirements into designs
  • You will help to create and maintain application documentation (i.e. user manuals, training documents)
  • You will participate in other Informatics related projects, as necessary and assigned
  • You will actively develop skills and keep up to date with new technologies and languages (e.g. Git, JavaScript, Python, UNIX Systems, SQL and cloud services)


Key requirements for the role:

  • You must be comfortable taking on significant technical challenges and be able to demonstrate creativity in solving them. This role would suit a self-starter, confident in your own technical abilities and ability to see projects through to finish
  • Exposure to DMPK in a commercial CRO environment would be advantageous and/or a life sciences background
  • Experience in developing/working with LIMS systems would be beneficial, or working with LC-MS/MS data outputs
  • Good experience in Integrating 3rd party software, modern web applications applications, ELN, SDMS, and instrumentation
  • Some experience of working/programming laboratory automation equipment would be favourable
  • Application development and programming skills in at least some of the following: Python, Ruby, Javascript/Typscript, Excel VBA
  • Web development: Python Django, Flask, Node or similar (ideally with experience working with Flask or Django)
  • Microsoft PowerApps
  • React, Vue or Angular
  • Git
  • Preference for Azure cloud services
  • Linux
  • Understanding of bioinformatics, data science or statistics
  • Data visualisation


Consideration will be given to other candidates that have demonstrable ability in other modern languages or web frameworks.

In return you will receive an excellent training and benefits package, including a highly competitive salary which is reviewed annually, a bonus scheme, a well-regarded pension scheme, and private medical insurance. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share in our success.

We also recognise that the environment you work in is a priority, so we have built a collaborative and supportive culture with plenty of opportunities to grow and succeed, tailored to individual and business needs. This includes an excellent set of bespoke training and development courses to accelerate both your scientific and personal career growth.

Sygnature Discovery is a highly respected, successful and award-winning provider of fully integrated drug discovery research programmes to the global pharmaceutical industry. Founded in 2004 with a workforce of six, we now employee over 300 scientists, mainly operating from our purpose-built facilities in BioCity, Nottingham, but also at Alderley Park, Cheshire. As part of our success and continued expansion, we are looking for innovative and enthusiastic computational chemists to join the organisation.

If you are interested in joining a successful and engaged company that places its people at the heart of its business, please apply through the link including the following:

Apply here

  1. Your CV
  2. a covering letter that briefly outlines your suitability for the role and your current notice period (if applicable)
  3. confirmation of your status of eligibility to work in the UK (we are able to consider sponsoring potential employees with relevant levels of qualifications and experience under a Skilled Worker Visa)


Your application will be submitted through our trusted partners, LogicMelon, although only employees of Sygnature Discovery will review your application and personal data.

We will be interviewing on an ongoing basis, so please submit your application as soon as possible. We look forward to hearing from you.

If you have any questions or need further information, please contact the Careers team at Please do not submit your application to this email address.

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