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Associate Director, DMPK – Nottingham or Alderley Park

DMPK Scientists at Sygnature Discovery play an essential role in supporting client projects. This growing department is looking for a talented DMPK Associate Director to push and lead our capabilities even further.

As a DMPK Associate Director, you will join a dynamic department actively discovering new drugs for a broad range of projects, molecular targets and therapeutic indications.

Associate Director responsibilities:

  • You will represent DMPK as the subject matter expert on Sygnature Discovery’s client project teams creating relationships with internal colleagues and clients.
  • Co-ordinating with Bioscience and Chemistry you will provide scientific and managerial leadership to their team in prioritizing and executing on key deliverables and project needs guiding programs through lead optimisation.
  • You will support the recruitment and retaining of key talent to maintain a high-performing team and be involved in the strategic direction of DMPK at Sygnature.
  • You will contribute to Sygnature Discovery’s DMPK recruitment needs, capital budget and implementation plans
  • You will need to support business development activities

Experience / Requirements:

  • B.Sc., M.Sc. and/or Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry or related disciplines with thorough knowledge of absorption, distribution, drug metabolism and pharmacokinetics
  • Broad experience in working with cross functional project teams to support drug discovery and/or pre-clinical development
  • Extensive experience of biotech and/or pharmaceutical industry experience in discovery DMPK
  • Demonstrated leadership and project management skills
  • Outstanding written and verbal communication skills

In return you will receive an excellent training and benefits package, including a highly competitive salary and pension scheme. All our benefits are tailored to enhancing your experience at Sygnature as it is important to us that you share our success. We also recognise that our environment is paramount, so we foster a collaborative and supportive culture with plenty of opportunities to grow and develop, tailored to individual and business needs.

We are an award-winning provider of fully integrated drug discovery research programmes to the global pharmaceutical industry. Our clients place great value on our highly flexible, transparent and collaborative business model. Our continuing growth has been supported by our move to the Discovery building, a purpose-built facility on the BioCity site in the heart of Nottingham. Sygnature also has a second site at Alderley Park which is rapidly expanding in 2021 to provide a second integrated drug discovery facility.

If you are interested in joining a successful and engaged company that places its people at the heart of its business, please apply through the link above including the following;

Apply here:

1) Your CV,

2) a covering letter that briefly outlines your suitability for the role and your current notice period (if applicable), and

3) confirmation of your status of eligibility to work in the UK (we are able to consider sponsoring potential employees with relevant levels of qualifications and experience under a Skilled Worker visa).

4) confirmation of which site you would like to be considered for.


Your application will be submitted through our trusted partners, LogicMelon, although only employees of Sygnature Discovery will review your application and personal data.

We will be interviewing on an ongoing basis, so please submit your application as soon as possible. We look forward to hearing from you.

If you have any questions or need further information, please contact the Careers team at Please do not submit your application to this email address.


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