Sygnature Discovery, Mironid®, and Peak Proteins to collaborate to discover new therapies for life-threatening and currently incurable kidney disease, ADPKD
Sygnature Discovery, Mironid® Limited, a leader in cell signalling-directed drug discovery and Peak Proteins, have announced they will work closely together to discover new therapies against diseases driven by elevated cyclic AMP (cAMP), such as Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is a devastating, life-threatening and currently incurable genetic disorder in which kidney cysts […]
Pelago Bioscience and Sygnature Discovery collaborate to Provide CETSA® based Target Engagement Assays
Sygnature Discovery today announced that it will collaborate with Pelago Bioscience, a Swedish biotech company to provide target engagement assays with Pelago’s patented Cellular Thermal Shift Assay (CETSA®) method. While target engagement has long been recognised as pivotal to targeted drug efficacy. Pelago’s CETSA method adds a new dimension to this valuable assay, as it […]
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Meet Sygnature at the following Conferences throughout 2015:
Biotech Showcase/JP Morgan
9-11th January 2017
San Francisco USA
RSC OrgSyn 50
27-28 February 2017
Proventa Medicinal Chemistry Strategy
14th March 2017
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KINASE INHIBITORS, FRICKEL, Fritz-Frieder
KINASE INHIBITORS, FRICKEL, Fritz-Frieder; FYFE, Matthew, Colin, Thor; MEGHANI, Premji; THOM, Stephen, Malcolm; (RespiVert Ltd. and TopiVert Ltd.), WO 2014076484 (2014).
PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS, DUFFY, Lorna Anne
PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS, DUFFY, Lorna Anne; KING-UNDERWOOD, John; LONGSHAW, Alistair Ian; MURRAY, Peter John; ONIONS, Stuart Thomas; TADDEI, David Michael Adrien; WILLIAMS, Jonathan Gareth; ITO, Kazuhiro; CHARRON, Catherine Elisabeth; (GB) (RespiVert Ltd. and TopiVert Ltd.), WO 2014033448 (2014).
KINASE INHIBITORS, FYFE, Matthew Colin Thor
KINASE INHIBITORS, FYFE, Matthew Colin Thor; MEGHANI, Premji; STENT, Matthew Alexander Henry; THOM, Stephen Malcolm; WALSHE, Claire Anne; (RespiVert Ltd. and TopiVert Ltd.), WO 2014033447 (2014).
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Scientists & Senior Scientists (Medicinal Chemistry)