Capabilities

  • Medicinal Chemistry

    Sygnature Discovery’s Medicinal Chemistry department provides expertise on integrated drug discovery projects and chemistry-only projects. Sygnature has recruited a large international team of pharmaceutical industry-experienced medicinal chemists (mainly PhD qualified bench scientists).

  • Bioscience

    Sygnature's in vitro Bioscience group are highly experienced scientists, many with considerable drug discovery experience gained in pharmaceutical companies and have worked as project leaders, scientific leaders and bench bioscientists at all stages of drug discovery.

  • Computational Sciences and Informatics

    Our Computational Sciences team supports drug discovery projects during target analysis, hit identification, hit to lead and lead optimisation. Sygnature also offers computational chemistry as a stand-alone capability.

  • DMPK and Physical Sciences

    Our DMPK Department is dedicated to the understanding of the absorption, distribution, metabolism and excretion of drug candidates. Our experienced DMPK scientists work in close partnership with the client and other departments within Sygnature, such as Medicinal Chemistry, Bioscience and Computational Sciences.

  • Protein Crystallography

    Sygnature Discovery offers protein expression and production, and X-ray crystallography as part of an integrated drug discovery project via its sister company Peak Proteins.

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